Non-NMDAR neuronal Ca2+–permeable channels in delayed neuronal death and as potential therapeutic targets for ischemic brain damage

Molecular Biophysics of Orai Store-Operated Ca2+ Channels

(2015) Anna Amcheslavsky et al.   BIOPHYSICAL JOURNAL

TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1

(2014) Guofeng Gao et al.   JOURNAL OF CLINICAL INVESTIGATION

Prolonged Adenosine A1 Receptor Activation in Hypoxia and Pial Vessel Disruption Focal Cortical Ischemia Facilitates Clathrin-Mediated AMPA Receptor Endocytosis and Long-Lasting Synaptic Inhibition in Rat Hippocampal CA3-CA1 Synapses: Differential Regulation of GluA2 and GluA1 Subunits by p38 MAPK and JNK

(2014) Z. Chen et al.   JOURNAL OF NEUROSCIENCE

TRPM2 channels mediate acetaminophen-induced liver damage

(2014) E. Kheradpezhouh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proton-sensitive cation channels and ion exchangers in ischemic brain injury: New therapeutic targets for stroke?

(2014) Tiandong Leng et al.   PROGRESS IN NEUROBIOLOGY

Transient Receptor Potential Melastatin Subfamily Member 2 Cation Channel Regulates Detrimental Immune Cell Invasion in Ischemic Stroke

(2014) Mathias Gelderblom et al.   STROKE

TRPM2 channel deficiency prevents delayed cytosolic Zn2+ accumulation and CA1 pyramidal neuronal death after transient global ischemia

(2014) M Ye et al.   Cell Death & Disease

Analysis of ischemic neuronal injury in CaV2.1 channel α1 subunit mutant mice

(2013) Xiaoli Tian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A positive allosteric modulator of α7 nAChRs augments neuroprotective effects of endogenous nicotinic agonists in cerebral ischaemia

(2013) Bopanna I Kalappa et al.   BRITISH JOURNAL OF PHARMACOLOGY

Androgen and PARP-1 Regulation of TRPM2 Channels after Ischemic Injury

(2013) Takeru Shimizu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Sexually Dimorphic Response of TRPM2 Inhibition Following Cardiac Arrest-Induced Global Cerebral Ischemia in Mice

(2013) S. Nakayama et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Modulation of NMDAR Subunit Expression by TRPM2 Channels Regulates Neuronal Vulnerability to Ischemic Cell Death

(2013) I. Alim et al.   JOURNAL OF NEUROSCIENCE

Molecular Mechanism of Constitutive Endocytosis of Acid-Sensing Ion Channel 1a and Its Protective Function in Acidosis-Induced Neuronal Death

(2013) W.-Z. Zeng et al.   JOURNAL OF NEUROSCIENCE

Disruption of the GluR2/GAPDH complex protects against ischemia-induced neuronal damage

(2013) Dongxu Zhai et al.   NEUROBIOLOGY OF DISEASE

Amiloride but Not Memantine Reduces Neurodegeneration, Seizures and Myoclonic Jerks in Rats with Cardiac Arrest-Induced Global Cerebral Hypoxia and Reperfusion

(2013) Kwok Keung Tai et al.   PLoS One

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

Teaching the basics of redox biology to medical and graduate students: Oxidants, antioxidants and disease mechanisms

(2013) Balaraman Kalyanaraman   Redox Biology

Ionotropic receptors and ion channels in ischemic neuronal death and dysfunction

(2012) Nicholas L Weilinger et al.   ACTA PHARMACOLOGICA SINICA

Novel neuroprotective effect of cisternal and intra-cerebral magnesium sulfate solution infusion on delayed cerebral death in rat hippocampal neurons after transient global ischemia

(2012) Kentaro Mori et al.   BRAIN RESEARCH

Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus

(2012) Ketan Chu et al.   Journal of Neuroinflammation

TRPM2 channel activation following in vitro ischemia contributes to male hippocampal cell death

(2012) S. Verma et al.   NEUROSCIENCE LETTERS

Redox signal-mediated sensitization of transient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions

(2012) M. Kashio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of the Calcium Release-Activated Calcium Channel Orai

(2012) X. Hou et al.   SCIENCE

Direct interaction between GluR2 and GAPDH regulates AMPAR-mediated excitotoxicity

(2012) Min Wang et al.   Molecular Brain

Hypoxia Induces an Increase in Intracellular Magnesium via Transient Receptor Potential Melastatin 7 (TRPM7) Channels in Rat Hippocampal Neuronsin Vitro

(2011) Jing Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sex Differences in Neuroprotection Provided by Inhibition of TRPM2 Channels following Experimental Stroke

(2011) Jia Jia et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Heteromeric Acid-Sensing Ion Channels (ASICs) Composed of ASIC2b and ASIC1a Display Novel Channel Properties and Contribute to Acidosis-Induced Neuronal Death

(2011) T. W. Sherwood et al.   JOURNAL OF NEUROSCIENCE

Extracellular Spermine Exacerbates Ischemic Neuronal Injury through Sensitization of ASIC1a Channels to Extracellular Acidosis

(2011) B. Duan et al.   JOURNAL OF NEUROSCIENCE

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

Neuroprotective effect of acid-sensing ion channel inhibitor psalmotoxin-1 after hypoxia–ischemia in newborn piglet striatum

(2011) Zeng-Jin Yang et al.   NEUROBIOLOGY OF DISEASE

Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes

(2011) H. Knowles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zinc: new clues to diverse roles in brain ischemia

(2011) C. William Shuttleworth et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection

(2010) Hai Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

Pathophysiologically Relevant Levels of Hydrogen Peroxide Induce Glutamate-Independent Neurodegeneration That Involves Activation of Transient Receptor Potential Melastatin 7 Channels

(2010) Emily Coombes et al.   ANTIOXIDANTS & REDOX SIGNALING

ASIC1a channels are activated by endogenous protons during ischemia and contribute to synergistic potentiation of intracellular Ca2+ overload during ischemia and acidosis

(2010) Yelenis Mari et al.   CELL CALCIUM

TRPM2 channel properties, functions and therapeutic potentials

(2010) Lin-Hua Jiang et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Zinc-induced Neurotoxicity Mediated by Transient Receptor Potential Melastatin 7 Channels

(2010) Koichi Inoue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of TRPC6 degradation suppresses ischemic brain damage in rats

(2010) Wanlu Du et al.   JOURNAL OF CLINICAL INVESTIGATION

Developmental change in the electrophysiological and pharmacological properties of acid-sensing ion channels in CNS neurons

(2010) Minghua Li et al.   JOURNAL OF PHYSIOLOGY-LONDON

Risk Factors and Prevention of Stroke in the Chinese Population

(2010) Qian Jia et al.   Journal of Stroke & Cerebrovascular Diseases

Store-operated CRAC channels: function in health and disease

(2010) Anant B. Parekh   NATURE REVIEWS DRUG DISCOVERY

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

(2010) S. F. Traynelis et al.   PHARMACOLOGICAL REVIEWS

Rising Zinc: A Significant Cause of Ischemic Neuronal Death in the CA1 Region of Rat Hippocampus

(2009) Christian J Stork et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Intracellular Zn2+ Accumulation Contributes to Synaptic Failure, Mitochondrial Depolarization, and Cell Death in an Acute Slice Oxygen-Glucose Deprivation Model of Ischemia

(2009) Y. V. Medvedeva et al.   JOURNAL OF NEUROSCIENCE

Dynorphin Opioid Peptides Enhance Acid-Sensing Ion Channel 1a Activity and Acidosis-Induced Neuronal Death

(2009) T. W. Sherwood et al.   JOURNAL OF NEUROSCIENCE

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

(2009) Alexander I. Sobolevsky et al.   NATURE

Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia

(2009) Hong-Shuo Sun et al.   NATURE NEUROSCIENCE

STIM2 Regulates Capacitive Ca2+ Entry in Neurons and Plays a Key Role in Hypoxic Neuronal Cell Death

(2009) A. Berna-Erro et al.   Science Signaling

TRPV1 stimulation triggers apoptotic cell death of rat cortical neurons

(2008) Hisashi Shirakawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TrkA pathway(s) is involved in regulation of TRPM7 expression in hippocampal neurons subjected to ischemic-reperfusion and oxygen–glucose deprivation

(2008) Hui Jiang et al.   BRAIN RESEARCH BULLETIN

Identification of Pore Residues Engaged in Determining Divalent Cationic Permeation in Transient Receptor Potential Melastatin Subtype Channel 2

(2008) Rong Xia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Poly(ADP-ribose) Polymerase PARP-1 Is Required for Oxidative Stress-induced TRPM2 Activation in Lymphocytes

(2008) Ben Buelow et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

China's battle with stroke

(2008) The Lancet Neurology   LANCET NEUROLOGY

The cost of cerebral ischaemia

(2008) R.W.V. Flynn et al.   NEUROPHARMACOLOGY

Purinergic signalling in the nervous system: an overview

(2008) Maria P. Abbracchio et al.   TRENDS IN NEUROSCIENCES