Therapeutic uses of furin and its inhibitors: a patent review

Proprotein Convertase Inhibition Results in Decreased Ski Proliferation, Tumorigenesis, and Metastasis

(2015) Daniel E. Bassi et al.   NEOPLASIA

X-ray Structures of Human Furin in Complex with Competitive Inhibitors

(2014) Sven O. Dahms et al.   ACS Chemical Biology

Molecular Validation of PACE4 as a Target in Prostate Cancer

(2014) François D'Anjou et al.   Translational Oncology

Optimization of Furin Inhibitors To Protect against the Activation of Influenza Hemagglutinin H5 and Shiga Toxin

(2013) Hugo Gagnon et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, and Structure–Activity Relationship Studies of a Potent PACE4 Inhibitor

(2013) Anna Kwiatkowska et al.   JOURNAL OF MEDICINAL CHEMISTRY

A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype

(2012) Anne-Marie Malfait et al.   ANNALS OF THE RHEUMATIC DISEASES

Protective role of systemic furin in immune response-induced arthritis

(2012) Hilène Lin et al.   ARTHRITIS AND RHEUMATISM

The Future of Peptide-based Drugs

(2012) David J. Craik et al.   Chemical Biology & Drug Design

SKI-1 and Furin Generate Multiple RGMa Fragments that Regulate Axonal Growth

(2012) Nardos G. Tassew et al.   DEVELOPMENTAL CELL

Highly Potent Inhibitors of Proprotein Convertase Furin as Potential Drugs for Treatment of Infectious Diseases

(2012) Gero L. Becker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Multi-Leu Peptide Inhibitor Discriminates Between PACE4 and Furin And Exhibits Antiproliferative Effects On Prostate Cancer Cells

(2012) Christine Levesque et al.   JOURNAL OF MEDICINAL CHEMISTRY

The biology and therapeutic targeting of the proprotein convertases

(2012) Nabil G. Seidah et al.   NATURE REVIEWS DRUG DISCOVERY

Proteolytic processing of vascular endothelial growth factor-D is essential for its capacity to promote the growth and spread of cancer

(2011) Nicole C. Harris et al.   FASEB JOURNAL

Phase I Trial of “bi-shRNAifurin/GMCSF DNA/Autologous Tumor Cell” Vaccine (FANG) in Advanced Cancer

(2011) Neil Senzer et al.   MOLECULAR THERAPY

Proprotein Convertases in Health and Disease

(2011) Andrew W. Artenstein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Partial maturation: an immune-evasion strategy of dengue virus?

(2011) Izabela A. Rodenhuis-Zybert et al.   TRENDS IN MICROBIOLOGY

Nona-D-Arginine Amide Suppresses Corneal Cytokines in Pseudomonas aeruginosa Keratitis

(2010) Priyanka Karicherla et al.   CORNEA

Nona-D-Arginine Amide for Prophylaxis and Treatment of ExperimentalPseudomonas aeruginosaKeratitis

(2010) Priyanka Karicherla et al.   CURRENT EYE RESEARCH

Selective and potent furin inhibitors protect cells from anthrax without significant toxicity

(2010) Albert G. Remacle et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Anti-inflammatory and pro-inflammatory roles of TGF-β, IL-10, and IL-22 in immunity and autoimmunity

(2009) Shomyseh Sanjabi et al.   CURRENT OPINION IN PHARMACOLOGY

BRI3 Inhibits Amyloid Precursor Protein Processing in a Mechanistically Distinct Manner from Its Homologue Dementia Gene BRI2

(2009) Shuji Matsuda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Potent Inhibitors of Furin and Furin-like Proprotein Convertases Containing Decarboxylated P1 Arginine Mimetics

(2009) Gero L. Becker et al.   JOURNAL OF MEDICINAL CHEMISTRY

Knock-out mouse models of proprotein convertases: unique functions or redundancy?

(2008) John et al.   Frontiers in Bioscience-Landmark

T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance

(2008) Marko Pesu et al.   NATURE