Cross-Linking/Mass Spectrometry for Studying Protein Structures and Protein-Protein Interactions: Where Are We Now and Where Should We Go from Here?

Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome

(2017) Xiaorong Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

6S RNA Mimics B-Form DNA to Regulate Escherichia coli RNA Polymerase

(2017) James Chen et al.   MOLECULAR CELL

Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex

(2017) Youwei Xu et al.   Nature Communications

A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex

(2017) Roman Teimer et al.   Nature Communications

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification

(2017) Fan Liu et al.   Nature Communications

Divide and conquer: cleavable cross-linkers to study protein conformation and protein–protein interactions

(2016) Andrea Sinz   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Integrated Workflow for Structural Proteomics Studies Based on Cross-Linking/Mass Spectrometry with an MS/MS Cleavable Cross-Linker

(2016) Christian Arlt et al.   ANALYTICAL CHEMISTRY

Optimized Fragmentation Regime for Diazirine Photo-Cross-Linked Peptides

(2016) Sven H. Giese et al.   ANALYTICAL CHEMISTRY

An Integrated Mass Spectrometry Based Approach to Probe the Structure of the Full-Length Wild-Type Tetrameric p53 Tumor Suppressor

(2016) Christian Arlt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structure and Function of the Nuclear Pore Complex Cytoplasmic mRNA Export Platform

(2016) Javier Fernandez-Martinez et al.   CELL

Conformational insight into multi-protein signaling assemblies by hydrogen–deuterium exchange mass spectrometry

(2016) Rane A Harrison et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

The Evolving Contribution of Mass Spectrometry to Integrative Structural Biology

(2016) Marco Faini et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Crosslinking and Mass Spectrometry: An Integrated Technology to Understand the Structure and Function of Molecular Machines

(2016) Alexander Leitner et al.   TRENDS IN BIOCHEMICAL SCIENCES

Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP

(2016) Carol Sheppard et al.   Nature Communications

Interrogating the architecture of protein assemblies and protein interaction networks by cross-linking mass spectrometry

(2015) Fan Liu et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry

(2015) Fan Liu et al.   NATURE METHODS

Chemical cross-linking and native mass spectrometry: A fruitful combination for structural biology

(2015) Andrea Sinz et al.   PROTEIN SCIENCE

The complete structure of the 55S mammalian mitochondrial ribosome

(2015) B. J. Greber et al.   SCIENCE

Fast Photochemical Oxidation of Proteins (FPOP) Maps the Epitope of EGFR Binding to Adnectin

(2014) Yuetian Yan et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Structural Model of a CRISPR RNA-Silencing Complex Reveals the RNA-Target Cleavage Activity in Cmr4

(2014) Christian Benda et al.   MOLECULAR CELL

Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes

(2014) Alexander Leitner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrated Structural Analysis of the Human Nuclear Pore Complex Scaffold

(2013) Khanh Huy Bui et al.   CELL

In Vivo Protein Interaction Network Identified with a Novel Real-Time Cross-Linked Peptide Identification Strategy

(2013) Chad R. Weisbrod et al.   JOURNAL OF PROTEOME RESEARCH

Quantitative cross-linking/mass spectrometry using isotope-labelled cross-linkers

(2013) Lutz Fischer et al.   Journal of Proteomics

Cross-Link Guided Molecular Modeling with ROSETTA

(2013) Abdullah Kahraman et al.   PLoS One

Comparative cross-linking and mass spectrometry of an intact F-type ATPase suggest a role for phosphorylation

(2013) Carla Schmidt et al.   Nature Communications

Intrinsically disordered proteins undergo and assist folding transitions in the proteome

(2012) D. Kovacs et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Exploring membrane protein structural features by oxidative labeling and mass spectrometry

(2012) Lars Konermann et al.   Expert Review of Proteomics

Mapping the Structural Topology of the Yeast 19S Proteasomal Regulatory Particle Using Chemical Cross-linking and Probabilistic Modeling

(2012) Athit Kao et al.   MOLECULAR & CELLULAR PROTEOMICS

In vivo protein complex topologies: Sights through a cross-linking lens

(2012) James E. Bruce   PROTEOMICS

Chemical cross-linkers for protein structure studies by mass spectrometry

(2012) David Paramelle et al.   PROTEOMICS

Joining Forces: Integrating Proteomics and Cross-linking with the Mass Spectrometry of Intact Complexes

(2011) Florian Stengel et al.   MOLECULAR & CELLULAR PROTEOMICS

Quaternary structure of the specific p53–DNA complex reveals the mechanism of p53 mutant dominance

(2011) Ricardo Aramayo et al.   NUCLEIC ACIDS RESEARCH

How useful is ion mobility mass spectrometry for structural biology? The relationship between protein crystal structures and their collision cross sections in the gas phase

(2010) Ewa Jurneczko et al.   ANALYST

Cleavable Cross-Linker for Protein Structure Analysis: Reliable Identification of Cross-Linking Products by Tandem MS

(2010) Mathias Q. Müller et al.   ANALYTICAL CHEMISTRY

Hydrogen exchange mass spectrometry for studying protein structure and dynamics

(2010) Lars Konermann et al.   CHEMICAL SOCIETY REVIEWS

The beginning of a beautiful friendship: Cross-linking/mass spectrometry and modelling of proteins and multi-protein complexes

(2010) Juri Rappsilber   JOURNAL OF STRUCTURAL BIOLOGY

How far can we go with structural mass spectrometry of protein complexes?

(2010) Michal Sharon   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Crosslinking combined with mass spectrometry for structural proteomics

(2010) Evgeniy V. Petrotchenko et al.   MASS SPECTROMETRY REVIEWS

Probing Native Protein Structures by Chemical Cross-linking, Mass Spectrometry, and Bioinformatics

(2010) Alexander Leitner et al.   MOLECULAR & CELLULAR PROTEOMICS

Computational modeling of laminin N-terminal domains using sparse distance constraints from disulfide bonds and chemical cross-linking

(2010) Stefan Kalkhof et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Intra-Molecular Cross-Linking of Acidic Residues for Protein Structure Studies

(2009) Petr Novák et al.   EUROPEAN JOURNAL OF MASS SPECTROMETRY

Chemical cross-linking with NHS esters: a systematic study on amino acid reactivities

(2009) Stefanie Mädler et al.   JOURNAL OF MASS SPECTROMETRY

Mass spectrometric identification of formaldehyde-induced peptide modifications under in vivo protein cross-linking conditions

(2008) Judy Toews et al.   ANALYTICA CHIMICA ACTA

Chances and pitfalls of chemical cross-linking with amine-reactive N-hydroxysuccinimide esters

(2008) Stefan Kalkhof et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Utility of formaldehyde cross-linking and mass spectrometry in the study of protein–protein interactions

(2008) Brent W. Sutherland et al.   JOURNAL OF MASS SPECTROMETRY

Native mass spectrometry: a bridge between interactomics and structural biology

(2008) Albert J R Heck   NATURE METHODS