Total Chemical Synthesis of SUMO and SUMO-Based Probes for Profiling the Activity of SUMO-Specific Proteases

Ubiquitin Signaling: Chemistry Comes to the Rescue

(2017) Sachitanand M. Mali et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total chemical synthesis of SUMO-2-Lys63-linked diubiquitin hybrid chains assisted by removable solubilizing tags

(2017) Somasekhar Bondalapati et al.   Chemical Science

Quantitative Chemical Proteomic Profiling of Ubiquitin Specific Proteases in Intact Cancer Cells

(2016) Jennifer A. Ward et al.   ACS Chemical Biology

How Chemical Synthesis of Ubiquitin Conjugates Helps To Understand Ubiquitin Signal Transduction

(2016) Dharjath S. Hameed et al.   BIOCONJUGATE CHEMISTRY

Development of Diubiquitin-Based FRET Probes To Quantify Ubiquitin Linkage Specificity of Deubiquitinating Enzymes

(2016) Paul P. Geurink et al.   CHEMBIOCHEM

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation

(2016) Kuan-Chuan Pao et al.   Nature Chemical Biology

A cascading activity-based probe sequentially targets E1–E2–E3 ubiquitin enzymes

(2016) Monique P C Mulder et al.   Nature Chemical Biology

Total chemical synthesis of SUMO proteins

(2016) Oleg Melnyk et al.   TETRAHEDRON LETTERS

One-pot chemical synthesis of small ubiquitin-like modifier protein–peptide conjugates using bis(2-sulfanylethyl)amido peptide latent thioester surrogates

(2015) Emmanuelle Boll et al.   Nature Protocols

Traceless Preparation of C-Terminal α-Ketoacids for Chemical Protein Synthesis by α-Ketoacid-Hydroxylamine Ligation: Synthesis of SUMO2/3

(2014) Thomas G. Wucherpfennig et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Native Chemical Ligation Handle that Enables the Synthesis of Advanced Activity-Based Probes: Diubiquitin as a Case Study

(2014) Monique P. C. Mulder et al.   CHEMBIOCHEM

Covalent inhibition of SUMO and ubiquitin-specific cysteine proteases by an in situ thiol–alkyne addition

(2013) Stefanie Sommer et al.   BIOORGANIC & MEDICINAL CHEMISTRY

On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases

(2013) Reggy Ekkebus et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Heat shock induces a massive but differential inactivation of SUMO-specific proteases

(2012) Manuel P. Pinto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Glycine Fluoromethylketones as SENP-Specific Activity Based Probes

(2011) Cristian Dobrotă et al.   CHEMBIOCHEM

Proteome-wide post-translational modification statistics: frequency analysis and curation of the swiss-prot database

(2011) George A. Khoury et al.   Scientific Reports

The SUMO protease SENP6 is essential for inner kinetochore assembly

(2010) Debaditya Mukhopadhyay et al.   JOURNAL OF CELL BIOLOGY

Characterization of SENP7, a SUMO-2/3-specific isopeptidase

(2009) Lin Nan Shen et al.   BIOCHEMICAL JOURNAL

Structure of the Human SENP7 Catalytic Domain and Poly-SUMO Deconjugation Activities for SENP6 and SENP7

(2008) Christopher D. Lima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY