Recentin vivoadvances in cell-penetrating peptide-assisted drug delivery

Activable Cell-Penetrating Peptide Conjugated Prodrug for Tumor Targeted Drug Delivery

(2015) Hong Cheng et al.   ACS Applied Materials & Interfaces

Peptide Assembly Integration of Fibroblast-Targeting and Cell-Penetration Features for Enhanced Antitumor Drug Delivery

(2015) Tianjiao Ji et al.   ADVANCED MATERIALS

Biodegradable Stearylated Peptide with Internal Disulfide Bonds for Efficient Delivery of siRNA In Vitro and In Vivo

(2015) Zongguang Tai et al.   BIOMACROMOLECULES

A near-infrared two-photon-sensitive peptide-mediated liposomal delivery system

(2015) Yang Yang et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

PEG shielded MMP sensitive CPPs for efficient and tumor specific gene delivery in vivo

(2015) Kadi-Liis Veiman et al.   JOURNAL OF CONTROLLED RELEASE

Tumor targeting of a cell penetrating peptide by fusing with a pH-sensitive histidine-glutamate co-oligopeptide

(2014) Likun Fei et al.   BIOMATERIALS

A survey on “Trojan Horse” peptides: Opportunities, issues and controlled entry to “Troy”

(2014) Nian-Qiu Shi et al.   JOURNAL OF CONTROLLED RELEASE

Combination of antibody targeting and PTD-mediated intracellular toxin delivery for colorectal cancer therapy

(2014) Meong Cheol Shin et al.   JOURNAL OF CONTROLLED RELEASE

Dual Targeting of Integrin  v 3 and Matrix Metalloproteinase-2 for Optical Imaging of Tumors and Chemotherapeutic Delivery

(2014) J. L. Crisp et al.   MOLECULAR CANCER THERAPEUTICS

Angiopep-2 and Activatable Cell-Penetrating Peptide Dual-Functionalized Nanoparticles for Systemic Glioma-Targeting Delivery

(2014) Huile Gao et al.   MOLECULAR PHARMACEUTICS

Peptide-Based Glioma-Targeted Drug Delivery Vector gHoPe2

(2013) Elo Eriste et al.   BIOCONJUGATE CHEMISTRY

PSA-responsive and PSMA-mediated multifunctional liposomes for targeted therapy of prostate cancer

(2013) Bai Xiang et al.   BIOMATERIALS

A pH-responsive α-helical cell penetrating peptide-mediated liposomal delivery system

(2013) Qianyu Zhang et al.   BIOMATERIALS

Chemotherapeutic drug delivery to cancer cells using a combination of folate targeting and tumor microenvironment-sensitive polypeptides

(2013) Wei Gao et al.   BIOMATERIALS

Doxorubicin in TAT peptide-modified multifunctional immunoliposomes demonstrates increased activity against both drug-sensitive and drug-resistant ovarian cancer models

(2013) Anjali Apte et al.   CANCER BIOLOGY & THERAPY

Octa-arginine-modified pegylated liposomal doxorubicin: An effective treatment strategy for non-small cell lung cancer

(2013) Swati Biswas et al.   CANCER LETTERS

Surface functionalization of doxorubicin-loaded liposomes with octa-arginine for enhanced anticancer activity

(2013) Swati Biswas et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

In Vivo Targeting of Hydrogen Peroxide by Activatable Cell-Penetrating Peptides

(2013) Roy Weinstain et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Complexation of Cell-Penetrating Peptide–Polymer Conjugates with Polyanions Controls Cells Uptake of HPMA Copolymers and Anti-tumor Activity

(2013) Yosi Shamay et al.   PHARMACEUTICAL RESEARCH

Enhanced anticancer activity of nanopreparation containing an MMP2-sensitive PEG-drug conjugate and cell-penetrating moiety

(2013) L. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influence of stearyl and trifluoromethylquinoline modifications of the cell penetrating peptide TP10 on its interaction with a lipid membrane

(2012) Maja Anko et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Dual-functional liposomes based on pH-responsive cell-penetrating peptide and hyaluronic acid for tumor-targeted anticancer drug delivery

(2012) Tianyue Jiang et al.   BIOMATERIALS

Cell-penetrating peptides for the delivery of nucleic acids

(2012) Taavi Lehto et al.   Expert Opinion on Drug Delivery

Vascular-targeted nanotherapy for obesity: Unexpected passive targeting mechanism to obese fat for the enhancement of active drug delivery

(2012) Md. Nazir Hossen et al.   JOURNAL OF CONTROLLED RELEASE

Size-controlled, dual-ligand modified liposomes that target the tumor vasculature show promise for use in drug-resistant cancer therapy

(2012) Kazuhiro Takara et al.   JOURNAL OF CONTROLLED RELEASE

Acid-Active Cell-Penetrating Peptides for in Vivo Tumor-Targeted Drug Delivery

(2012) Erlei Jin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thermal Targeting of an Acid-Sensitive Doxorubicin Conjugate of Elastin-like Polypeptide Enhances the Therapeutic Efficacy Compared with the Parent Compound In Vivo

(2012) S. Moktan et al.   MOLECULAR CANCER THERAPEUTICS

RVG-Mediated Calpain2 Gene Silencing in the Brain Impairs Learning and Memory

(2012) Sohila Zadran et al.   NEUROMOLECULAR MEDICINE

Targeted Delivery of Proteins into the Central Nervous System Mediated by Rabies Virus Glycoprotein-Derived Peptide

(2012) Ailing Fu et al.   PHARMACEUTICAL RESEARCH

Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4

(2012) Y. Ren et al.   Science Translational Medicine

Cell-Penetrating Peptides, PepFects, Show No Evidence of Toxicity and ImmunogenicityIn VitroandIn Vivo

(2011) Julia Suhorutsenko et al.   BIOCONJUGATE CHEMISTRY

Systemic delivery of siRNA to tumors using a lipid nanoparticle containing a tumor-specific cleavable PEG-lipid

(2011) Hiroto Hatakeyama et al.   BIOMATERIALS

The efficiency of tumor-specific pH-responsive peptide-modified polymeric micelles containing paclitaxel

(2011) Bing-Xiang Zhao et al.   BIOMATERIALS

Cell penetrating peptide-mediated systemic siRNA delivery to the liver

(2011) Yasuhiro Hayashi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Octaarginine- and pH sensitive fusogenic peptide-modified nanoparticles for liver gene delivery

(2011) Ikramy A. Khalil et al.   JOURNAL OF CONTROLLED RELEASE

Targeted Gene Modification of Hematopoietic Progenitor Cells in Mice Following Systemic Administration of a PNA-peptide Conjugate

(2011) Faye A Rogers et al.   MOLECULAR THERAPY

Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo

(2011) Samir EL Andaloussi et al.   NUCLEIC ACIDS RESEARCH

A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: A strategy for overcoming the PEG dilemma

(2010) Hiroto Hatakeyama et al.   ADVANCED DRUG DELIVERY REVIEWS

Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases

(2010) E. S. Olson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival

(2010) Q. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer

(2009) Emilia S. Olson et al.   Integrative Biology

Systemic in vivo distribution of activatable cell penetrating peptides is superior to that of cell penetrating peptides

(2009) Todd A. Aguilera et al.   Integrative Biology

Auger Radiation-Induced, Antisense-Mediated Cytotoxicity of Tumor Cells Using a 3-Component Streptavidin-Delivery Nanoparticle with 111In

(2009) X. Liu et al.   JOURNAL OF NUCLEAR MEDICINE

Efficient siRNA delivery into primary cells by a peptide transduction domain–dsRNA binding domain fusion protein

(2009) Akiko Eguchi et al.   NATURE BIOTECHNOLOGY

Targeting cyclin B1 through peptide-based delivery of siRNA prevents tumour growth

(2009) L. Crombez et al.   NUCLEIC ACIDS RESEARCH

T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice

(2008) Priti Kumar et al.   CELL

Super pH-sensitive multifunctional polymeric micelle for tumor pHe specific TAT exposure and multidrug resistance

(2008) Eun Seong Lee et al.   JOURNAL OF CONTROLLED RELEASE

Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo

(2008) Erik Henke et al.   NATURE BIOTECHNOLOGY

Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters

(2008) E. A. Dubikovskaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protease-Triggered Unveiling of Bioactive Nanoparticles

(2008) Todd J. Harris et al.   Small

Design of a Tumor-Homing Cell-Penetrating Peptide

(2007) Helena Myrberg et al.   BIOCONJUGATE CHEMISTRY