Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo

Induction of in vivo synthetic lethal RNAi responses to treat glioblastoma

(2010) Hiroyuki Michiue et al.   CANCER BIOLOGY & THERAPY

Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation☆

(2010) Hidetaka Akita et al.   JOURNAL OF CONTROLLED RELEASE

Noninvasive Imaging of Lipid Nanoparticle–Mediated Systemic Delivery of Small-Interfering RNA to the Liver

(2010) Weikang Tao et al.   MOLECULAR THERAPY

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Tissue-specific gene delivery via nanoparticle coating

(2009) Todd J. Harris et al.   BIOMATERIALS

Twenty years of cell-penetrating peptides: from molecular mechanisms to therapeutics

(2009) Frederic Heitz et al.   BRITISH JOURNAL OF PHARMACOLOGY

RNAi-based therapeutics-current status, challenges and prospects

(2009) Katrin Tiemann et al.   EMBO Molecular Medicine

Chemically modified cell-penetrating peptides for the delivery of nucleic acids

(2009) Maarja Mäe et al.   Expert Opinion on Drug Delivery

A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo

(2009) Hiroto Hatakeyama et al.   JOURNAL OF CONTROLLED RELEASE

The promises and pitfalls of RNA-interference-based therapeutics

(2009) Daniela Castanotto et al.   NATURE

Efficient siRNA delivery into primary cells by a peptide transduction domain–dsRNA binding domain fusion protein

(2009) Akiko Eguchi et al.   NATURE BIOTECHNOLOGY

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting cyclin B1 through peptide-based delivery of siRNA prevents tumour growth

(2009) L. Crombez et al.   NUCLEIC ACIDS RESEARCH

Analysis of in vitro toxicity of five cell-penetrating peptides by metabolic profiling

(2009) Kalle Kilk et al.   TOXICOLOGY

Distinct Uptake Routes of Cell-Penetrating Peptide Conjugates

(2008) Per Lundin et al.   BIOCONJUGATE CHEMISTRY

T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice

(2008) Priti Kumar et al.   CELL

Overcoming the Innate Immune Response to Small Interfering RNA

(2008) Adam Judge et al.   HUMAN GENE THERAPY

A stearylated CPP for delivery of splice correcting oligonucleotides using a non-covalent co-incubation strategy

(2008) Maarja Mäe et al.   JOURNAL OF CONTROLLED RELEASE

Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast

(2008) Lyris M. F. de Godoy et al.   NATURE

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3

(2008) Mark E. Kleinman et al.   NATURE

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

(2008) Akin Akinc et al.   NATURE BIOTECHNOLOGY

Chemical Modification Patterns Compatible with High Potency Dicer-Substrate Small Interfering RNAs

(2008) Michael A. Collingwood et al.   OLIGONUCLEOTIDES

Quantitative membrane proteomics applying narrow range peptide isoelectric focusing for studies of small cell lung cancer resistance mechanisms

(2008) Hanna Eriksson et al.   PROTEOMICS

Enhancing the cellular uptake of siRNA duplexes following noncovalent packaging with protein transduction domain peptides

(2007) Bryan R. Meade et al.   ADVANCED DRUG DELIVERY REVIEWS

Delivery of proteins and nucleic acids using a non-covalent peptide-based strategy

(2007) Sébastien Deshayes et al.   ADVANCED DRUG DELIVERY REVIEWS