Cerebrospinal fluid and vitreous body exposure to orally administered tafamidis in hereditary ATTRV30M (p.TTRV50M) amyloidosis patients

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

Inhibition of amyloid beta fibril formation by monomeric human transthyretin

(2018) Kanchan Garai et al.   PROTEIN SCIENCE

Age-dependent cognitive dysfunction in untreated hereditary transthyretin amyloidosis

(2017) Ana Martins da Silva et al.   JOURNAL OF NEUROLOGY

Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients

(2017) Joseph D. Schonhoft et al.   Science Translational Medicine

Suppressing transthyretin production in mice, monkeys and humans using 2nd-Generation antisense oligonucleotides

(2016) Elizabeth J. Ackermann et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

CSF, blood-brain barrier, and brain drug delivery

(2016) William M. Pardridge   Expert Opinion on Drug Delivery

Transthyretin Suppresses Amyloid-β Secretion by Interfering with Processing of the Amyloid-β Protein Precursor

(2016) Xinyi Li et al.   JOURNAL OF ALZHEIMERS DISEASE

Cerebral amyloid angiopathy in posttransplant patients with hereditary ATTR amyloidosis

(2016) Yoshiki Sekijima et al.   NEUROLOGY

Personalized medicine approach for optimizing the dose of tafamidis to potentially ameliorate wild-type transthyretin amyloidosis (cardiomyopathy)

(2015) Younhee Cho et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Ophthalmological manifestations in hereditary transthyretin (ATTR V30M) carriers: a review of 513 cases

(2015) João Melo Beirão et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Transthyretin (ATTR) amyloidosis: clinical spectrum, molecular pathogenesis and disease-modifying treatments

(2015) Yoshiki Sekijima   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Plasma Transthyretin as a Biomarker of Lean Body Mass and Catabolic States

(2015) Yves Ingenbleek et al.   Advances in Nutrition

Repurposing Diflunisal for Familial Amyloid Polyneuropathy

(2015) John L. Berk et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Quantification of Transthyretin Kinetic Stability in Human Plasma Using Subunit Exchange

(2014) Irit Rappley et al.   BIOCHEMISTRY

CNS involvement in V30M transthyretin amyloidosis: clinical, neuropathological and biochemical findings

(2014) L. F. Maia et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Safety and Efficacy of RNAi Therapy for Transthyretin Amyloidosis

(2013) Teresa Coelho et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tafamidis for transthyretin familial amyloid polyneuropathy: A randomized, controlled trial

(2012) T. Coelho et al.   NEUROLOGY

Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade

(2012) C. E. Bulawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of Liver Transplantation on Transthyretin-Related Ocular Amyloidosis in Japanese Patients

(2010) Ryuhei Hara   ARCHIVES OF OPHTHALMOLOGY

A Stilbene That Binds Selectively to Transthyretin in Cells and Remains Dark until It Undergoes a Chemoselective Reaction To Create a Bright Blue Fluorescent Conjugate

(2010) Sungwook Choi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY