B Cells Producing Type I IFN Modulate Macrophage Polarization in Tuberculosis

Detection of interferon alpha protein reveals differential levels and cellular sources in disease

(2017) Mathieu P. Rodero et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antibodies to Mycobacterium tuberculosis

(2017) Arturo Casadevall   NEW ENGLAND JOURNAL OF MEDICINE

A Functional Role for Antibodies in Tuberculosis

(2016) Lenette L. Lu et al.   CELL

Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques

(2016) Jiayao Phuah et al.   INFECTION AND IMMUNITY

Different Risk of Tuberculosis and Efficacy of Isoniazid Prophylaxis in Rheumatoid Arthritis Patients with Biologic Therapy: A Nationwide Retrospective Cohort Study in Taiwan

(2016) Tsai-Ling Liao et al.   PLoS One

Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment

(2016) Simone A. Joosten et al.   PLoS Pathogens

The human immune response to tuberculosis and its treatment: a view from the blood

(2015) Jacqueline M. Cliff et al.   IMMUNOLOGICAL REVIEWS

A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis

(2015) Bappaditya Dey et al.   NATURE MEDICINE

Proinflammatory GM-CSF–producing B cells in multiple sclerosis and B cell depletion therapy

(2015) Rui Li et al.   Science Translational Medicine

Lung-Residing Myeloid-derived Suppressors Display Dual Functionality in Murine Pulmonary Tuberculosis

(2014) Julia K. Knaul et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Type I IFN signaling triggers immunopathology in tuberculosis-susceptible mice by modulating lung phagocyte dynamics

(2014) Anca Dorhoi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

TLR-Activated B Cells Suppress T Cell-Mediated Autoimmunity

(2014) V. Lampropoulou et al.   JOURNAL OF IMMUNOLOGY

Type I IFN Induces IL-10 Production in an IL-27–Independent Manner and Blocks Responsiveness to IFN-γ for Production of IL-12 and Bacterial Killing inMycobacterium tuberculosis–Infected Macrophages

(2014) Finlay W. McNab et al.   JOURNAL OF IMMUNOLOGY

Deletion of the cyclic di-AMP phosphodiesterase gene (cnpB) inMycobacterium tuberculosisleads to reduced virulence in a mouse model of infection

(2014) Jun Yang et al.   MOLECULAR MICROBIOLOGY

Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

(2014) Katrin D. Mayer-Barber et al.   NATURE

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

(2014) Ping Shen et al.   NATURE

The role of B cells and humoral immunity in Mycobacterium tuberculosis infection

(2014) John Chan et al.   SEMINARS IN IMMUNOLOGY

Modified Vaccinia Virus Ankara Triggers Type I IFN Production in Murine Conventional Dendritic Cells via a cGAS/STING-Mediated Cytosolic DNA-Sensing Pathway

(2014) Peihong Dai et al.   PLoS Pathogens

Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell Types

(2014) Elena Tomasello et al.   Frontiers in Immunology

The Immune Response in Tuberculosis

(2013) Anne O'Garra et al.   Annual Review of Immunology

Differential and Site Specific Impact of B Cells in the Protective Immune Response to Mycobacterium tuberculosis in the Mouse

(2013) Egídio Torrado et al.   PLoS One

B Cells Regulate Neutrophilia during Mycobacterium tuberculosis Infection and BCG Vaccination by Modulating the Interleukin-17 Response

(2013) Lee Kozakiewicz et al.   PLoS Pathogens

Cytokine-producing B cells as regulators of pathogenic and protective immune responses

(2012) Simon Fillatreau   ANNALS OF THE RHEUMATIC DISEASES

INTERFEROME v2.0: an updated database of annotated interferon-regulated genes

(2012) Irina Rusinova et al.   NUCLEIC ACIDS RESEARCH

Common patterns and disease-related signatures in tuberculosis and sarcoidosis

(2012) J. Maertzdorf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel regulatory functions for Toll-like receptor-activated B cells during intracellular bacterial infection

(2011) Simon Fillatreau   IMMUNOLOGICAL REVIEWS

MPYS Is Required for IFN Response Factor 3 Activation and Type I IFN Production in the Response of Cultured Phagocytes to Bacterial Second Messengers Cyclic-di-AMP and Cyclic-di-GMP

(2011) L. Jin et al.   JOURNAL OF IMMUNOLOGY

Macrophage polarization to a unique phenotype driven by B cells

(2010) Siew-Cheng Wong et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Signaling via the MyD88 Adaptor Protein in B Cells Suppresses Protective Immunity during Salmonella typhimurium Infection

(2010) Patricia Neves et al.   IMMUNITY

Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population

(2010) Lis R.V. Antonelli et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: Mincle Is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analog Trehalose-Dibehenate

(2010) H. Schoenen et al.   JOURNAL OF IMMUNOLOGY

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

(2010) Matthew P. R. Berry et al.   NATURE

B Cells Delay Neutrophil Migration toward the Site of Stimulus: Tardiness Critical for Effective Bacillus Calmette-Guerin Vaccination against Tuberculosis Infection in Mice

(2009) T. K. Kondratieva et al.   JOURNAL OF IMMUNOLOGY

TLR2-Dependent Inhibition of Macrophage Responses to IFN-γ Is Mediated by Distinct, Gene-Specific Mechanisms

(2009) Sarah A. Benson et al.   PLoS One

Tumor Necrosis Factor Blockade in Chronic Murine Tuberculosis Enhances Granulomatous Inflammation and Disorganizes Granulomas in the Lungs

(2008) S. D. Chakravarty et al.   INFECTION AND IMMUNITY