A novel mtDNA repair fusion protein attenuates maladaptive remodeling and preserves cardiac function in heart failure

Regulation of mitochondrial genome replication by hypoxia: The role of DNA oxidation in D-loop region

(2016) Viktor M. Pastukh et al.   FREE RADICAL BIOLOGY AND MEDICINE

The fibrosis-cell death axis in heart failure

(2016) A. Piek et al.   HEART FAILURE REVIEWS

Sustained release nitrite therapy results in myocardial protection in a porcine model of metabolic syndrome with peripheral vascular disease

(2015) Jessica M. Bradley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mitochondrially targeted Endonuclease III has a powerful anti-infarct effect in an in vivo rat model of myocardial ischemia/reperfusion

(2015) Xi-Ming Yang et al.   BASIC RESEARCH IN CARDIOLOGY

Nitrite Therapy Improves Left Ventricular Function During Heart Failure via Restoration of Nitric Oxide–Mediated Cytoprotective Signaling

(2014) Shashi Bhushan et al.   CIRCULATION RESEARCH

Mitochondria-targeted Ogg1 and Aconitase-2 Prevent Oxidant-induced Mitochondrial DNA Damage in Alveolar Epithelial Cells

(2014) Seok-Jo Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

H 2 S Protects Against Pressure Overload–Induced Heart Failure via Upregulation of Endothelial Nitric Oxide Synthase

(2013) Kazuhisa Kondo et al.   CIRCULATION

Hydrogen Sulfide Attenuates Cardiac Dysfunction After Heart Failure Via Induction of Angiogenesis

(2013) David J. Polhemus et al.   Circulation-Heart Failure

Exposure to diesel exhaust particulates induces cardiac dysfunction and remodeling

(2013) Jessica M. Bradley et al.   JOURNAL OF APPLIED PHYSIOLOGY

Mitochondrial-targeted DNA repair enzyme 8-oxoguanine DNA glycosylase 1 protects against ventilator-induced lung injury in intact mice

(2012) Masahiro Hashizume et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Mitochondrial DNA damage and its consequences for mitochondrial gene expression

(2012) Susan D. Cline   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Mitochondria, Myocardial Remodeling, and Cardiovascular Disease

(2012) Hugo E. Verdejo et al.   CURRENT HYPERTENSION REPORTS

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

(2012) Takafumi Oka et al.   NATURE

Cardiac overexpression of 8-oxoguanine DNA glycosylase 1 protects mitochondrial DNA and reduces cardiac fibrosis following transaortic constriction

(2011) Jianxun Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mitochondrial DNA integrity may be a determinant of endothelial barrier properties in oxidant-challenged rat lungs

(2011) Joshua M. Chouteau et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

TNF-α increases cardiac fibroblast lysyl oxidase expression through TGF-β and PI3Kinase signaling pathways

(2011) Tetyana G. Voloshenyuk et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial proteome remodelling in pressure overload-induced heart failure: the role of mitochondrial oxidative stress

(2011) Dao-Fu Dai et al.   CARDIOVASCULAR RESEARCH

Mitochondrial Targeted Antioxidant Peptide Ameliorates Hypertensive Cardiomyopathy

(2011) Dao-Fu Dai et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

PGC-1α Regulates Expression of Myocardial Mitochondrial Antioxidants and Myocardial Oxidative Stress After Chronic Systolic Overload

(2010) Zhongbing Lu et al.   ANTIOXIDANTS & REDOX SIGNALING

The DNA glycosylase Ogg1 defends against oxidant-induced mtDNA damage and apoptosis in pulmonary artery endothelial cells

(2010) Mykhaylo V. Ruchko et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial DNA damage and repair in neurodegenerative disorders

(2008) Jenq-Lin Yang et al.   DNA REPAIR