Comparative genomics reveals conservation of filaggrin and loss of caspase-14 in dolphins

Trichohyalin-Like Proteins Have Evolutionarily Conserved Roles in the Morphogenesis of Skin Appendages

(2014) Veronika Mlitz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Evolutionary Origin and Diversification of Epidermal Barrier Proteins in Amniotes

(2014) Bettina Strasser et al.   MOLECULAR BIOLOGY AND EVOLUTION

The sheep genome illuminates biology of the rumen and lipid metabolism

(2014) Y. Jiang et al.   SCIENCE

Molecular evolution tracks macroevolutionary transitions in Cetacea

(2014) Michael R. McGowen et al.   TRENDS IN ECOLOGY & EVOLUTION

Proteases: common culprits in human skin disorders

(2014) Simon J. de Veer et al.   TRENDS IN MOLECULAR MEDICINE

Multiple pathways are involved in DNA degradation during keratinocyte terminal differentiation

(2014) M Yamamoto-Tanaka et al.   Cell Death & Disease

Association of caspase-14 and filaggrin expression with keratinization of the oral mucosa and reconstruction culture rat models

(2013) H. Murakami et al.   JOURNAL OF PERIODONTAL RESEARCH

Minke whale genome and aquatic adaptation in cetaceans

(2013) Hyung-Soon Yim et al.   NATURE GENETICS

Characterization of canine filaggrin: gene structure and protein expression in dog skin

(2013) Satoko Kanda et al.   VETERINARY DERMATOLOGY

Whales Use Distinct Strategies to Counteract Solar Ultraviolet Radiation

(2013) Laura M. Martinez-Levasseur et al.   Scientific Reports

The skin surface as antimicrobial barrier: present concepts and future outlooks

(2012) Jürgen Harder et al.   EXPERIMENTAL DERMATOLOGY

The human epidermal differentiation complex: cornified envelope precursors, S100 proteins and the ‘fused genes’ family

(2012) Magdalini Kypriotou et al.   EXPERIMENTAL DERMATOLOGY

Altered stratum corneum barrier and enhanced percutaneous immune responses in filaggrin-null mice

(2012) Hiroshi Kawasaki et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Whale phylogeny and rapid radiation events revealed using novel retroposed elements and their flanking sequences

(2011) Zhuo Chen et al.   BMC EVOLUTIONARY BIOLOGY

SASPase regulates stratum corneum hydration through profilaggrin-to-filaggrin processing

(2011) Takeshi Matsui et al.   EMBO Molecular Medicine

Update on the epidermal differentiation complex

(2011) Julie Henry   Frontiers in Bioscience-Landmark

Identification of the C-terminal tail domain of AHF/trichohyalin as the critical site for modulation of the keratin filamentous meshwork in the keratinocyte

(2011) Takahisa Takase et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Caspase-14 Is Required for Filaggrin Degradation to Natural Moisturizing Factors in the Skin

(2011) Esther Hoste et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Impact of filaggrin mutations on Raman spectra and biophysical properties of the stratum corneum in mild to moderate atopic dermatitis

(2011) V. Mlitz et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Phylogenomic analyses and improved resolution of Cetartiodactyla

(2011) Xuming Zhou et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

A high-resolution map of human evolutionary constraint using 29 mammals

(2011) Kerstin Lindblad-Toh et al.   NATURE

Raman profiles of the stratum corneum define 3 filaggrin genotype–determined atopic dermatitis endophenotypes

(2010) Gráinne M. O'Regan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Knockdown of Filaggrin Impairs Diffusion Barrier Function and Increases UV Sensitivity in a Human Skin Model

(2010) Michael Mildner et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Increased Sensitivity of Histidinemic Mice to UVB Radiation Suggests a Crucial Role of Endogenous Urocanic Acid in Photoprotection

(2010) Caterina Barresi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Natural moisturizing factor components in the stratum corneum as biomarkers of filaggrin genotype: evaluation of minimally invasive methods

(2009) S. Kezic et al.   BRITISH JOURNAL OF DERMATOLOGY

Filaggrin in the frontline: role in skin barrier function and disease

(2009) A. Sandilands et al.   JOURNAL OF CELL SCIENCE

The skin: an indispensable barrier

(2008) Ehrhardt Proksch et al.   EXPERIMENTAL DERMATOLOGY

Identification of Novel Mammalian Caspases Reveals an Important Role of Gene Loss in Shaping the Human Caspase Repertoire

(2008) L. Eckhart et al.   MOLECULAR BIOLOGY AND EVOLUTION

Identification of reptilian genes encoding hair keratin-like proteins suggests a new scenario for the evolutionary origin of hair

(2008) L. Eckhart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Water Distribution and Natural Moisturizer Factor Content in Human Skin Equivalents Are Regulated by Environmental Relative Humidity

(2007) Joke A. Bouwstra et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY