The human epidermal differentiation complex: cornified envelope precursors, S100 proteins and the ‘fused genes’ family

Psoriasis Risk Genes of the Late Cornified Envelope-3 Group Are Distinctly Expressed Compared with Genes of Other LCE Groups

(2011) Judith G.M. Bergboer et al.   AMERICAN JOURNAL OF PATHOLOGY

S100 and S100 fused-type protein families in epidermal maturation with special focus on S100A3 in mammalian hair cuticles

(2011) Kenji Kizawa et al.   BIOCHIMIE

Homeodomain-only protein HOP is a novel modulator of late differentiation in keratinocytes

(2011) Magdalena Obarzanek-Fojt et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

A large-scale multi-technique approach identifies forty-nine new players of keratinocyte terminal differentiation in human epidermis

(2011) Nicolas R. Mattiuzzo et al.   EXPERIMENTAL DERMATOLOGY

Hornerin is a component of the epidermal cornified cell envelopes

(2011) Julie Henry et al.   FASEB JOURNAL

Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy

(2011) Sara J. Brown et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Comparative proteomic profiling of patients with atopic dermatitis based on history of eczema herpeticum infection and Staphylococcus aureus colonization

(2011) Carolyn J. Broccardo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

TALE homeodomain proteins regulate site-specific terminal differentiation, LCE genes and epidermal barrier

(2011) B. Jackson et al.   JOURNAL OF CELL SCIENCE

Association Screening in the Epidermal Differentiation Complex (EDC) Identifies an SPRR3 Repeat Number Variant as a Risk Factor for Eczema

(2011) Ingo Marenholz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Identification of Trichohyalin-Like 1, an S100 Fused-Type Protein Selectively Expressed in Hair Follicles

(2011) Zhihong Wu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

TNF-α Downregulates Filaggrin and Loricrin through c-Jun N-terminal Kinase: Role for TNF-α Antagonists to Improve Skin Barrier

(2011) Byung Eui Kim et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

ROS Quenching Potential of the Epidermal Cornified Cell Envelope

(2011) Wilbert P. Vermeij et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Cornified Envelope: A First Line of Defense against Reactive Oxygen Species

(2011) Matthias Schäfer et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Filaggrin Mutations Associated with Skin and Allergic Diseases

(2011) Alan D. Irvine et al.   NEW ENGLAND JOURNAL OF MEDICINE

PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin

(2011) Simona Frateschi et al.   Nature Communications

Flaky Tail Mouse Denotes Human Atopic Dermatitis in the Steady State and by Topical Application with Dermatophagoides pteronyssinus Extract

(2010) Catharina Sagita Moniaga et al.   AMERICAN JOURNAL OF PATHOLOGY

Novel S100A7 (psoriasin)/S100A15 (koebnerisin) subfamily: highly homologous but distinct in regulation and function

(2010) Ronald Wolf et al.   AMINO ACIDS

Nrf2 establishes a glutathione-mediated gradient of UVB cytoprotection in the epidermis

(2010) M. Schafer et al.   GENES & DEVELOPMENT

Kallikrein-related Peptidase-8 (KLK8) Is an Active Serine Protease in Human Epidermis and Sweat and Is Involved in a Skin Barrier Proteolytic Cascade

(2010) Azza Eissa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing

(2010) Chrystelle Bonnart et al.   JOURNAL OF CLINICAL INVESTIGATION

The Antimicrobial Heterodimer S100A8/S100A9 (Calprotectin) Is Upregulated by Bacterial Flagellin in Human Epidermal Keratinocytes

(2010) Arby Abtin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Knockdown of Filaggrin Impairs Diffusion Barrier Function and Increases UV Sensitivity in a Human Skin Model

(2010) Michael Mildner et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Enhanced Expression and Secretion of Antimicrobial Peptides in Atopic Dermatitis and after Superficial Skin Injury

(2010) Jürgen Harder et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Increased Sensitivity of Histidinemic Mice to UVB Radiation Suggests a Crucial Role of Endogenous Urocanic Acid in Photoprotection

(2010) Caterina Barresi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Skin Cornification Proteins Provide Global Link between ROS Detoxification and Cell Migration during Wound Healing

(2010) Wilbert P. Vermeij et al.   PLoS One

Cornulin, a marker of late epidermal differentiation, is down-regulated in eczema

(2009) A. Liedén et al.   ALLERGY

Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway

(2009) Karin List et al.   AMERICAN JOURNAL OF PATHOLOGY

Reddish, scaly, and itchy: how proteases and their inhibitors contribute to inflammatory skin diseases

(2009) Ulf Meyer-Hoffert   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Ceramide biosynthesis in keratinocyte and its role in skin function

(2009) Yukiko Mizutani et al.   BIOCHIMIE

Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development

(2009) R. F. L. O'Shaughnessy et al.   DEVELOPMENT

Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens

(2009) Tiffany C. Scharschmidt et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

An interaction between filaggrin mutations and early food sensitization improves the prediction of childhood asthma

(2009) Ingo Marenholz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Filaggrin-deficient mice exhibit TH17-dominated skin inflammation and permissiveness to epicutaneous sensitization with protein antigen

(2009) Michiko K. Oyoshi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Filaggrin in the frontline: role in skin barrier function and disease

(2009) A. Sandilands et al.   JOURNAL OF CELL SCIENCE

Acute Acidification of Stratum Corneum Membrane Domains Using Polyhydroxyl Acids Improves Lipid Processing and Inhibits Degradation of Corneodesmosomes

(2009) Jean-Pierre Hachem et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis

(2009) Rafael de Cid et al.   NATURE GENETICS

A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming

(2009) Padraic G Fallon et al.   NATURE GENETICS

Molecular Identification and Expression Analysis of Filaggrin-2, a Member of the S100 Fused-Type Protein Family

(2009) Zhihong Wu et al.   PLoS One

TIG3: a regulator of type I transglutaminase activity in epidermis

(2008) Richard L. Eckert et al.   AMINO ACIDS

Transcriptomic dissection of tongue squamous cell carcinoma

(2008) Hui Ye et al.   BMC GENOMICS

Loricrin and involucrin expression is down-regulated by Th2 cytokines through STAT-6

(2008) Byung Eui Kim et al.   CLINICAL IMMUNOLOGY

Molecular elements of the regulatory control of keratin filament modulator AHF/trichohyalin in the hair follicle

(2008) Sachiya Yamamoto et al.   EXPERIMENTAL DERMATOLOGY

The burden of disease associated with filaggrin mutations: A population-based, longitudinal birth cohort study

(2008) John Henderson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Histidase expression in human epidermal keratinocytes: Regulation by differentiation status and all-trans retinoic acid

(2008) Leopold Eckhart et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Highly Complex Peptide Aggregates of the S100 Fused-Type Protein Hornerin Are Present in Human Skin

(2008) Zhihong Wu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding?

(2008) Sébastien Thibaut et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Ichthyosis, Follicular Atrophoderma, and Hypotrichosis Caused by Mutations in ST14 Is Associated with Impaired Profilaggrin Processing

(2008) Thomas Alef et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY