Cross-Linking of Thiolated Paclitaxel-Oligo(p -phenylene vinylene) Conjugates Aggregates inside Tumor Cells Leads to “Chemical Locks” That Increase Drug Efficacy

Enzyme-Regulated Supramolecular Assemblies of Cholesterol Conjugates against Drug-Resistant Ovarian Cancer Cells

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Intracellular Self-Assembly of Taxol Nanoparticles for Overcoming Multidrug Resistance

(2015) Yue Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing

(2015) Wujin Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Taurine Boosts Cellular Uptake of Small d-Peptides for Enzyme-Instructed Intracellular Molecular Self-Assembly

(2015) Jie Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cationic Oligo(p-phenylene vinylene) Materials for Combating Drug Resistance of Cancer Cells by Light Manipulation

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Potential role of tubulin tyrosine ligase-like enzymes in tumorigenesis and cancer cell resistance

(2014) Viswanath Das et al.   CANCER LETTERS

Targeting the Achilles Heel of Multidrug-Resistant Cancer by Exploiting the Fitness Cost of Resistance

(2014) Gergely Szakács et al.   CHEMICAL REVIEWS

Docetaxel–carboxymethylcellulose nanoparticles display enhanced anti-tumor activity in murine models of castration-resistant prostate cancer

(2014) Bryan Hoang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Ligand–Receptor Interaction Catalyzes the Aggregation of Small Molecules To Induce Cell Necroptosis

(2014) Junfeng Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fundamental Molecular Mechanism for the Cellular Uptake of Guanidinium-Rich Molecules

(2014) Henry D. Herce et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cell-Penetrating, Guanidinium-Rich Molecular Transporters for Overcoming Efflux-Mediated Multidrug Resistance

(2014) Jessica R. Vargas et al.   MOLECULAR PHARMACEUTICS

Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo

(2014) Deju Ye et al.   Nature Chemistry

Self-assembly-induced near-infrared fluorescent nanoprobes for effective tumor molecular imaging

(2014) Hao Wu et al.   Journal of Materials Chemistry B

Taxane resistance in breast cancer: Mechanisms, predictive biomarkers and circumvention strategies

(2012) S. Murray et al.   CANCER TREATMENT REVIEWS

Water-Soluble Conjugated Polymers for Imaging, Diagnosis, and Therapy

(2012) Chunlei Zhu et al.   CHEMICAL REVIEWS

DNA Origami as a Carrier for Circumvention of Drug Resistance

(2012) Qiao Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical Molecule-Induced Light-Activated System for Anticancer and Antifungal Activities

(2012) Huanxiang Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Imaging enzyme-triggered self-assembly of small molecules inside live cells

(2012) Yuan Gao et al.   Nature Communications

Self-Assembly of an Optically Active Conjugated Oligoelectrolyte

(2011) Julia H. Ortony et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Drug Resistance and Cellular Adaptation to Tumor Acidic pH Microenvironment

(2011) Jonathan W. Wojtkowiak et al.   MOLECULAR PHARMACEUTICS

The Emergence of Drug Transporter-Mediated Multidrug Resistance to Cancer Chemotherapy

(2011) Chung-Pu Wu et al.   MOLECULAR PHARMACEUTICS

A biocompatible condensation reaction for controlled assembly of nanostructures in living cells

(2009) Gaolin Liang et al.   Nature Chemistry

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY