Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo

Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation

(2013) Genevieve C. Van de Bittner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Inhibitor of Glutathione S-Transferase Omega 1 that Selectively Targets Apoptotic Cells

(2012) Nicholas J. Pace et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Caspase-Activated Cell-Penetrating Peptides Reveal Temporal Coupling Between Endosomal Release and Apoptosis in an RGC-5 Cell Model

(2012) James R. Johnson et al.   BIOCONJUGATE CHEMISTRY

Fluorescent Nanoprobes Dedicated to in Vivo Imaging: From Preclinical Validations to Clinical Translation

(2012) Juliette Mérian et al.   MOLECULES

Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria

(2012) Lihi Adler-Abramovich et al.   Nature Chemical Biology

Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction

(2012) Kathrin Lang et al.   Nature Chemistry

Reaction-based small-molecule fluorescent probes for chemoselective bioimaging

(2012) Jefferson Chan et al.   Nature Chemistry

A Pictet-Spengler ligation for protein chemical modification

(2012) P. Agarwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reactive polymer enables efficient in vivo bioorthogonal chemistry

(2012) N. K. Devaraj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging enzyme-triggered self-assembly of small molecules inside live cells

(2012) Yuan Gao et al.   Nature Communications

From Mechanism to Mouse: A Tale of Two Bioorthogonal Reactions

(2011) Ellen M. Sletten et al.   ACCOUNTS OF CHEMICAL RESEARCH

Controlling Intracellular Macrocyclization for the Imaging of Protease Activity

(2011) Deju Ye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The in vivo performance of an enzyme-assisted self-assembled peptide/protein hydrogel

(2011) Richard J. Williams et al.   BIOMATERIALS

Functional imaging of proteases: recent advances in the design and application of substrate-based and activity-based probes

(2011) Laura E Edgington et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Advances in the chemistry of small molecule fluorescent probes

(2011) Laura M Wysocki et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

On-demand drug delivery from self-assembled nanofibrous gels: A new approach for treatment of proteolytic disease

(2011) Praveen Kumar Vemula et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Noninvasive Imaging of Cell Death Using an Hsp90 Ligand

(2011) Danielle Park et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-mediated intracellular chemistry

(2011) Rahimi M. Yusop et al.   Nature Chemistry

Multi-hierarchical self-assembly of a collagen mimetic peptide from triple helix to nanofibre and hydrogel

(2011) Lesley E. R. O'Leary et al.   Nature Chemistry

In vivo imaging of tumor apoptosis using histone H1-targeting peptide

(2010) Kai Wang et al.   JOURNAL OF CONTROLLED RELEASE

Diversity for self-assembly

(2010) Ehud Gazit   Nature Chemistry

Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/trans-Cyclooctene Cycloaddition

(2009) Neal K. Devaraj et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Biocompatible Condensation Reaction for the Labeling of Terminal Cysteine Residues on Proteins

(2009) Hongjun Ren et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Improved Cell-Penetrating, Caspase-Activatable, Near-Infrared Fluorescent Peptide for Apoptosis Imaging

(2009) Dustin Maxwell et al.   BIOCONJUGATE CHEMISTRY

A biocompatible condensation reaction for controlled assembly of nanostructures in living cells

(2009) Gaolin Liang et al.   Nature Chemistry

Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes

(2009) Laura E Edgington et al.   NATURE MEDICINE

Blood levels of homocysteine, cysteine, glutathione, folic acid, and vitamin B12 in the acute phase of atherothrombotic stroke

(2009) Giuseppe Salemi et al.   NEUROLOGICAL SCIENCES

Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [18F]-labeled isatin sulfonamide

(2009) Q.-D. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enzymatic Hydrogelation of Small Molecules

(2008) Zhimou Yang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Visualizing Metabolically Labeled Glycoconjugates of Living Cells by Copper-Free and Fast Huisgen Cycloadditions

(2008) Xinghai Ning et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Vivo Detection of Apoptosis

(2008) F. G. Blankenberg   JOURNAL OF NUCLEAR MEDICINE

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

(2008) Melissa L. Blackman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Video-Rate Far-Field Optical Nanoscopy Dissects Synaptic Vesicle Movement

(2008) V. Westphal et al.   SCIENCE

In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish

(2008) S. T. Laughlin et al.   SCIENCE

Self-Assembly of Large and Small Molecules into Hierarchically Ordered Sacs and Membranes

(2008) R. M. Capito et al.   SCIENCE

Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3D Structured Illumination Microscopy

(2008) L. Schermelleh et al.   SCIENCE