Wnt signaling pathways in myocardial infarction and the therapeutic effects of Wnt pathway inhibitors

Targeting the Wnt/beta-catenin pathway in cancer: Update on effectors and inhibitors

(2018) Nithya Krishnamurthy et al.   CANCER TREATMENT REVIEWS

The allosteric glycogen synthase kinase-3 inhibitor NP12 limits myocardial remodeling and promotes angiogenesis in an acute myocardial infarction model

(2017) Jugajyoti Baruah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The extracellular matrix protein agrin promotes heart regeneration in mice

(2017) Elad Bassat et al.   NATURE

Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist

(2017) Jesung Moon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MiR-154 directly suppressesDKK2to activate Wnt signaling pathway and enhance activation of cardiac fibroblasts

(2016) Li-Ye Sun et al.   CELL BIOLOGY INTERNATIONAL

The Wnt signaling pathway in cancer

(2016) Yann Duchartre et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

The Janus face of myofibroblasts in the remodeling heart

(2016) Kevin C.M. Hermans et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Depression and coronary heart disease

(2016) Robert M. Carney et al.   Nature Reviews Cardiology

Distinctive Roles of Canonical and Noncanonical Wnt Signaling in Human Embryonic Cardiomyocyte Development

(2016) Silvia Mazzotta et al.   Stem Cell Reports

Wnt acylation and its functional implication in Wnt signalling regulation

(2015) Claudia Y. Janda et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Secreted Frizzled-related Protein 5 Diminishes Cardiac Inflammation and Protects the Heart from Ischemia/Reperfusion Injury

(2015) Kazuto Nakamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wnt5a-Induced Wnt1-Inducible Secreted Protein-1 Suppresses Vascular Smooth Muscle Cell Apoptosis Induced by Oxidative Stress

(2014) Carina Mill et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The inflammatory response in myocardial injury, repair and remodelling

(2014) Nikolaos G. Frangogiannis   Nature Reviews Cardiology

The Small Molecule Wnt Signaling Modulator ICG-001 Improves Contractile Function in Chronically Infarcted Rat Myocardium

(2013) Tomoyo Sasaki et al.   PLoS One

Myofibroblasts in the Infarct Area: Concepts and Challenges

(2012) Evangelos P. Daskalopoulos et al.   MICROSCOPY AND MICROANALYSIS

LRP5 and LRP6 in development and disease

(2012) Danese M. Joiner et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Secreted Frizzled-Related Protein-1 Improves Postinfarction Scar Formation Through a Modulation of Inflammatory Response

(2011) Laurent Barandon et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Discovering Small Molecules that Promote Cardiomyocyte Generation by Modulating Wnt Signaling

(2011) Terri T. Ni et al.   CHEMISTRY & BIOLOGY

Blocking of Frizzled Signaling With a Homologous Peptide Fragment of Wnt3a/Wnt5a Reduces Infarct Expansion and Prevents the Development of Heart Failure After Myocardial Infarction

(2011) Hilde Laeremans et al.   CIRCULATION

Experimental myocardial infarction triggers canonical Wnt signaling and endothelial-to-mesenchymal transition

(2011) O. Aisagbonhi et al.   Disease Models & Mechanisms

Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair

(2011) Jinzhu Duan et al.   EMBO JOURNAL

The WNT antagonist Dickkopf2 promotes angiogenesis in rodent and human endothelial cells

(2011) Jeong-Ki Min et al.   JOURNAL OF CLINICAL INVESTIGATION

Wnt3a Induces Myofibroblast Differentiation by Upregulating TGF-β Signaling Through SMAD2 in a β-Catenin-Dependent Manner

(2011) Jon M. Carthy et al.   PLoS One

Active Wnt signaling in response to cardiac injury

(2010) Martinus I. F. J. Oerlemans et al.   BASIC RESEARCH IN CARDIOLOGY

The Multiple Phases and Faces of Wnt Signaling During Cardiac Differentiation and Development

(2010) Susanne Gessert et al.   CIRCULATION RESEARCH

Pyrvinium, a Potent Small Molecule Wnt Inhibitor, Promotes Wound Repair and Post-MI Cardiac Remodeling

(2010) Sarika Saraswati et al.   PLoS One

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

Myocardial remodeling after infarction: the role of myofibroblasts

(2009) Susanne W. M. van den Borne et al.   Nature Reviews Cardiology

Planar Cell Polarity Signaling: From Fly Development to Human Disease

(2008) Matias Simons et al.   Annual Review of Genetics

Wnt5A/CaMKII Signaling Contributes to the Inflammatory Response of Macrophages and Is a Target for the Antiinflammatory Action of Activated Protein C and Interleukin-10

(2008) Claudia Pereira et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY