Influence of Nrf2 activators on subcellular skeletal muscle protein and DNA synthesis rates after 6 weeks of milk protein feeding in older adults

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer

(2016) Randy Strong et al.   AGING CELL

The role of Nrf2 in skeletal muscle contractile and mitochondrial function

(2016) Matthew J. Crilly et al.   JOURNAL OF APPLIED PHYSIOLOGY

Translating the Science of Aging into Therapeutic Interventions

(2016) James L. Kirkland   Cold Spring Harbor Perspectives in Medicine

Long-lived Snell dwarf mice display increased proteostatic mechanisms that are not dependent on decreased mTORC1 activity

(2015) Joshua C. Drake et al.   AGING CELL

Defects in Mitochondrial Efficiency and H2O2Emissions in Obese Women Are Restored to a Lean Phenotype With Aerobic Exercise Training

(2015) Adam R. Konopka et al.   DIABETES

Nrf2 Signaling and the Slowed Aging Phenotype: Evidence from Long-Lived Models

(2015) Danielle R. Bruns et al.   Oxidative Medicine and Cellular Longevity

The measurement of protein synthesis for assessing proteostasis in studies of slowed aging

(2014) Benjamin F. Miller et al.   AGEING RESEARCH REVIEWS

Long-lived crowded-litter mice have an age-dependent increase in protein synthesis to DNA synthesis ratio and mTORC1 substrate phosphorylation

(2014) Joshua C. Drake et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Greater muscle protein synthesis and mitochondrial biogenesis in males compared with females during sprint interval training

(2014) Rebecca L. Scalzo et al.   FASEB JOURNAL

Skeletal Muscle Mitochondrial Function and Fatigability in Older Adults

(2014) Adam J. Santanasto et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Exercise and Nutrition to Target Protein Synthesis Impairments in Aging Skeletal Muscle

(2013) Jared M. Dickinson et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Assessment of Mitochondrial Biogenesis and mTORC1 Signaling During Chronic Rapamycin Feeding in Male and Female Mice

(2013) Joshua C. Drake et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan

(2012) Michael J. Steinbaugh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Upregulation of phase II enzymes through phytochemical activation of Nrf2 protects cardiomyocytes against oxidant stress

(2012) Danielle J. Reuland et al.   FREE RADICAL BIOLOGY AND MEDICINE

Energy Balance Changes the Anabolic Effect of Postexercise Feeding in Older Individuals

(2012) B. D. Minor et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Calorie Restriction Does Not Increase Short-term or Long-term Protein Synthesis

(2012) B. F. Miller et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Skeletal Muscle Mitochondrial Energetics Are Associated With Maximal Aerobic Capacity and Walking Speed in Older Adults

(2012) Paul M. Coen et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Phytochemical Activation of Nrf2 Protects Human Coronary Artery Endothelial Cells against an Oxidative Challenge

(2012) Elise L. Donovan et al.   Oxidative Medicine and Cellular Longevity

A comprehensive assessment of mitochondrial protein synthesis and cellular proliferation with age and caloric restriction

(2011) Benjamin F. Miller et al.   AGING CELL

Long-term synthesis rates of skeletal muscle DNA and protein are higher during aerobic training in older humans than in sedentary young subjects but are not altered by protein supplementation

(2011) Matthew M. Robinson et al.   FASEB JOURNAL

Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation

(2011) Brooks M. Hybertson et al.   MOLECULAR ASPECTS OF MEDICINE

Conjugated linoleic acid protects against gliadin-induced depletion of intestinal defenses

(2011) Paolo Bergamo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Dysfunctional Nrf2–Keap1 redox signaling in skeletal muscle of the sedentary old

(2010) Adeel Safdar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Acute β-adrenergic stimulation does not alter mitochondrial protein synthesis or markers of mitochondrial biogenesis in adult men

(2009) Matthew M. Robinson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Hydrogen peroxide impairs insulin-stimulated assembly of mTORC1

(2009) Lianqin Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Presence of low-grade inflammation impaired postprandial stimulation of muscle protein synthesis in old rats

(2009) Michèle Balage et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Reduction of low grade inflammation restores blunting of postprandial muscle anabolism and limits sarcopenia in old rats

(2009) Isabelle Rieu et al.   JOURNAL OF PHYSIOLOGY-LONDON

Higher Inflammatory Marker Levels in Older Persons: Associations With 5-Year Change in Muscle Mass and Muscle Strength

(2009) L. A. Schaap et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Nrf2 Signaling, a Mechanism for Cellular Stress Resistance in Long-Lived Mice

(2009) S. F. Leiser et al.   MOLECULAR AND CELLULAR BIOLOGY

Synergistic induction of heme oxygenase-1 by the components of the antioxidant supplement Protandim

(2008) Kalpana Velmurugan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antioxidant Supplementation Restores Defective Leucine Stimulation of Protein Synthesis in Skeletal Muscle from Old Rats

(2008) Barbara Marzani et al.   JOURNAL OF NUTRITION