Genome sequencing as a platform for pharmacogenetic genotyping: a pediatric cohort study

Analysis of Genetic Variation in CYP450 Genes for Clinical Implementation

(2017) Liuh Ling Goh et al.   PLoS One

Comparison of genome sequencing and clinical genotyping for pharmacogenes

(2016) W Yang et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Rare genetic variants in cellular transporters, metabolic enzymes and nuclear receptors can be important determinants of interindividual differences in drug response

(2016) Mikael Kozyra et al.   GENETICS IN MEDICINE

Characterization of 137 Genomic DNA Reference Materials for 28 Pharmacogenetic Genes

(2016) Victoria M. Pratt et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

CYP2D6 copy number distribution in the US population

(2016) Michelle Beoris et al.   Pharmacogenetics and Genomics

Cross-Comparison of Exome Analysis, Next-Generation Sequencing of Amplicons, and the iPLEX® ADME PGx Panel for Pharmacogenomic Profiling

(2016) Eng Wee Chua et al.   Frontiers in Pharmacology

Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequences

(2016) Greyson P Twist et al.   npj Genomic Medicine

Whole-genome sequencing expands diagnostic utility and improves clinical management in paediatric medicine

(2016) Dimitri J Stavropoulos et al.   npj Genomic Medicine

Evaluation of somatic copy number estimation tools for whole-exome sequencing data

(2015) Jae-Yong Nam et al.   BRIEFINGS IN BIOINFORMATICS

Pharmacogenomics - how close/far are we to practising individualized medicine for children?

(2015) Chor-Wing Sing et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines forCYP3A5Genotype and Tacrolimus Dosing

(2015) KA Birdwell et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline forCYP2D6andCYP2C19Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors

(2015) JK Hicks et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Association Between Pharmacogenomics and Adverse Drug Reactions

(2015) Zhi-Wei Zhou et al.   DRUGS

Pharmacogenomics in the clinic

(2015) Mary V. Relling et al.   NATURE

Performance of exome sequencing for pharmacogenomics

(2015) Eric R Londin et al.   Personalized Medicine

Genetic variation in the human cytochrome P450 supergene family

(2015) Kohei Fujikura et al.   Pharmacogenetics and Genomics

The Clinical Pharmacogenetics Implementation Consortium Guideline for SLCO1B1 and Simvastatin-Induced Myopathy: 2014 Update

(2014) L B Ramsey et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Abacavir Dosing: 2014 Update

(2014) M A Martin et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450 2D6 Genotype and Codeine Therapy: 2014 Update

(2014) K R Crews et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Recommendations for HLA-B*15:02 and HLA-A*31:01 genetic testing to reduce the risk of carbamazepine-induced hypersensitivity reactions

(2014) Ursula Amstutz et al.   EPILEPSIA

Molecular Findings Among Patients Referred for Clinical Whole-Exome Sequencing

(2014) Yaping Yang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Computational tools for copy number variation (CNV) detection using next-generation sequencing data: features and perspectives

(2013) Min Zhao et al.   BMC BIOINFORMATICS

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for IFNL3 (IL28B) Genotype and PEG Interferon-α–Based Regimens

(2013) A J Muir et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing: 2013 Update

(2013) M V Relling et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Tricyclic Antidepressants

(2013) J K Hicks et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C19 Genotype and Clopidogrel Therapy: 2013 Update

(2013) S A Scott et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pediatric perspective on pharmacogenomics

(2013) Adam Stevens et al.   PHARMACOGENOMICS

Characterizing and measuring bias in sequence data

(2013) Michael G Ross et al.   GENOME BIOLOGY

Implementing Personalized Medicine: Development of a Cost-Effective Customized Pharmacogenetics Genotyping Array

(2012) J A Johnson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Primer3—new capabilities and interfaces

(2012) Andreas Untergasser et al.   NUCLEIC ACIDS RESEARCH

Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 Genotypes and Warfarin Dosing

(2011) J A Johnson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pharmacogenetics: From Bench to Byte— An Update of Guidelines

(2011) J J Swen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Computational Techniques for Human Genome Resequencing Using Mated Gapped Reads

(2011) Paolo Carnevali et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Characterization of 107 Genomic DNA Reference Materials for CYP2D6, CYP2C19, CYP2C9, VKORC1, and UGT1A1

(2010) Victoria M. Pratt et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

CYP2D7–2D6hybrid tandems: identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction

(2009) Andrea Gaedigk et al.   PHARMACOGENOMICS

Human Genome Sequencing Using Unchained Base Reads on Self-Assembling DNA Nanoarrays

(2009) R. Drmanac et al.   SCIENCE