Rare genetic variants in cellular transporters, metabolic enzymes and nuclear receptors can be important determinants of interindividual differences in drug response

From sample average treatment effect to population average treatment effect on the treated: combining experimental with observational studies to estimate population treatment effects

(2015) Erin Hartman et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY

Haplotype-resolved genome sequencing: experimental methods and applications

(2015) Matthew W. Snyder et al.   NATURE REVIEWS GENETICS

Genetic variation in the human cytochrome P450 supergene family

(2015) Kohei Fujikura et al.   Pharmacogenetics and Genomics

Pharmacogenomic information in drug labels: European Medicines Agency perspective

(2015) F Ehmann et al.   PHARMACOGENOMICS JOURNAL

Role of SLC22A1 polymorphic variants in drug disposition, therapeutic responses and drug–drug interactions

(2015) C Arimany-Nardi et al.   PHARMACOGENOMICS JOURNAL

Personalized Pharmacogenomics: Predicting Efficacy and Adverse Drug Reactions

(2014) Munir Pirmohamed   Annual Review of Genomics and Human Genetics

Replication of TPMT and ABCC3 Genetic Variants Highly Associated With Cisplatin-Induced Hearing Loss in Children

(2013) K Pussegoda et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Interactions of cytosolic sulfotransferases with xenobiotics

(2013) Margaret O. James et al.   DRUG METABOLISM REVIEWS

Glutathione transferase-A2 S112T polymorphism predicts survival, transplant-related mortality, busulfan and bilirubin blood levels after allogeneic stem cell transplantation

(2013) F. Bonifazi et al.   HAEMATOLOGICA

High Accuracyin SilicoSulfotransferase Models

(2013) Ian Cook et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Next-generation sequencing of pharmacogenes

(2013) Britt I. Drögemöller et al.   Pharmacogenetics and Genomics

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes

(2012) J. A. Tennessen et al.   SCIENCE

An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People

(2012) M. R. Nelson et al.   SCIENCE

Rare versus common variants in pharmacogenetics: SLCO1B1 variation and methotrexate disposition

(2011) L. B. Ramsey et al.   GENOME RESEARCH

The real cost of sequencing: higher than you think!

(2011) Andrea Sboner et al.   GENOME BIOLOGY

PharmGKB very important pharmacogene: SLCO1B1

(2010) Connie Oshiro et al.   Pharmacogenetics and Genomics

Xenobiotic Metabolism, Disposition, and Regulation by Receptors: From Biochemical Phenomenon to Predictors of Major Toxicities

(2010) C. J. Omiecinski et al.   TOXICOLOGICAL SCIENCES

Pharmacogenetics of Drug Transporters

(2009) R. Franke et al.   CURRENT PHARMACEUTICAL DESIGN

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

(2009) Anne T. Nies et al.   HEPATOLOGY

A pharmacogenetic study of docetaxel and thalidomide in patients with castration-resistant prostate cancer using the DMET genotyping platform

(2009) J F Deeken et al.   PHARMACOGENOMICS JOURNAL

African Genetic Diversity: Implications for Human Demographic History, Modern Human Origins, and Complex Disease Mapping

(2008) Michael C. Campbell et al.   Annual Review of Genomics and Human Genetics

The effect ofSLCO1B1polymorphism on repaglinide pharmacokinetics persists over a wide dose range

(2008) Annikka Kalliokoski et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacogenetic Predictors of Statin-Mediated Low-Density Lipoprotein Cholesterol Reduction and Dose Response

(2008) Deepak Voora et al.   Circulation-Cardiovascular Genetics

Bringing age-related macular degeneration into focus

(2008) Rando Allikmets et al.   NATURE GENETICS

Pharmacogenomic Biomarkers for Prediction of Severe Adverse Drug Reactions

(2008) Magnus Ingelman-Sundberg   NEW ENGLAND JOURNAL OF MEDICINE

SLCO1B1Variants and Statin-Induced Myopathy — A Genomewide Study

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

Pharmacogenomic Biomarker Information in Drug Labels Approved by the United States Food and Drug Administration: Prevalence of Related Drug Use

(2008) Felix W Frueh et al.   PHARMACOTHERAPY