Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequences

Points to Consider: Ethical, Legal, and Psychosocial Implications of Genetic Testing in Children and Adolescents

(2015) Jeffrey R. Botkin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cypiripi: exact genotyping ofCYP2D6using high-throughput sequencing data

(2015) Ibrahim Numanagić et al.   BIOINFORMATICS

Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting

(2015) LV Kalman et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline forCYP2D6andCYP2C19Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors

(2015) JK Hicks et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

CYP2D6 genetic polymorphisms and their relevance for poisoning due to amfetamines, opioid analgesics and antidepressants

(2015) Vincent Haufroid et al.   CLINICAL TOXICOLOGY

Clinical Association Between Pharmacogenomics and Adverse Drug Reactions

(2015) Zhi-Wei Zhou et al.   DRUGS

Effect of Cytochrome P450 polymorphism on the action and metabolism of selective serotonin reuptake inhibitors

(2015) Kristina Probst-Schendzielorz et al.   Expert Opinion on Drug Metabolism & Toxicology

Development of clinical decision support alerts for pharmacogenomic incidental findings from exome sequencing

(2015) Adam A. Nishimura et al.   GENETICS IN MEDICINE

CYP2D6 Haplotype Determination Using Long Range Allele-Specific Amplification

(2015) Andrea Gaedigk et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Genetic diagnosis of developmental disorders in the DDD study: a scalable analysis of genome-wide research data

(2015) Caroline F Wright et al.   LANCET

Genetic variation in the human cytochrome P450 supergene family

(2015) Kohei Fujikura et al.   Pharmacogenetics and Genomics

Individualizing the Use of Medications in Children: Making Goldilocks Happy

(2014) J S Leeder et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450 2D6 Genotype and Codeine Therapy: 2014 Update

(2014) K R Crews et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Challenges in CYP2D6 Phenotype Assignment from Genotype Data: A Critical Assessment and Call for Standardization

(2014) J. Hicks et al.   CURRENT DRUG METABOLISM

Large-scale discovery of novel genetic causes of developmental disorders

(2014) T. W. Fitzgerald et al.   NATURE

Integrating human sequence data sets provides a resource of benchmark SNP and indel genotype calls

(2014) Justin M Zook et al.   NATURE BIOTECHNOLOGY

Effect of CYP2D6, CYP2C9 and ABCB1 genotypes on fluoxetine plasma concentrations and clinical improvement in children and adolescent patients

(2014) P Gassó et al.   PHARMACOGENOMICS JOURNAL

Effectiveness of exome and genome sequencing guided by acuity of illness for diagnosis of neurodevelopmental disorders

(2014) S. E. Soden et al.   Science Translational Medicine

Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Tricyclic Antidepressants

(2013) J K Hicks et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Views of Genetics Health Professionals on the Return of Genomic Results

(2013) Megan E. Grove et al.   Journal of Genetic Counseling

Codeine-related adverse drug reactions in children following tonsillectomy: A prospective study

(2013) Cynthia A. Prows et al.   LARYNGOSCOPE

Next-generation sequencing of pharmacogenes

(2013) Britt I. Drögemöller et al.   Pharmacogenetics and Genomics

Characterization of the CYP2D6 gene locus and metabolic activity in Indo- and Afro-Trinidadians: discovery of novel allelic variants

(2013) Lazara Karelia Montané Jaime et al.   PHARMACOGENOMICS

Pharmacogenomics Knowledge for Personalized Medicine

(2012) M Whirl-Carrillo et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

CYP2D6 update

(2012) Sarah C. Sim et al.   Pharmacogenetics and Genomics

Rapid Whole-Genome Sequencing for Genetic Disease Diagnosis in Neonatal Intensive Care Units

(2012) C. J. Saunders et al.   Science Translational Medicine

Pharmacogenetics: From Bench to Byte— An Update of Guidelines

(2011) J J Swen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

CYP2D6,SULT1A1andUGT2B17copy number variation: quantitative detection by multiplex PCR

(2011) Andrea Gaedigk et al.   PHARMACOGENOMICS

Deep Sequencing of Patient Genomes for Disease Diagnosis: When Will It Become Routine?

(2011) S. F. Kingsmore et al.   Science Translational Medicine

Whole-Genome Sequencing for Optimized Patient Management

(2011) M. N. Bainbridge et al.   Science Translational Medicine

Fast and SNP-tolerant detection of complex variants and splicing in short reads

(2010) T. D. Wu et al.   BIOINFORMATICS

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Identification of Novel CYP2D7-2D6 Hybrids: Non-Functional and Functional Variants

(2010) Andrea Gaedigk et al.   Frontiers in Pharmacology

Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance

(2009) Shu-Feng Zhou   CLINICAL PHARMACOKINETICS

Polymorphism of Human Cytochrome P450 2D6 and Its Clinical Significance

(2009) Shu-Feng Zhou   CLINICAL PHARMACOKINETICS

CYP2D7–2D6hybrid tandems: identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction

(2009) Andrea Gaedigk et al.   PHARMACOGENOMICS