Article
Agriculture, Dairy & Animal Science
Carlotta Giromini, Simona Nonnis, David I. Givens, Julie A. Lovegrove, Raffaella Rebucci, Gabriella Tedeschi, Luciano Pinotti, Serena Reggi, Luciana Rossi, Antonella Baldi
Summary: Plant proteins, such as those from soy, contain bioactive peptides and proteins with antioxidant, ACE-inhibitory, anti-hypertensive, and antimicrobial activities. In this study, peptides and proteins produced during in vitro gastrointestinal digestion of soy protein isolate were found to have significant growth inhibitory effects on E. coli, supporting their potential antimicrobial properties. These findings suggest that soy-based supplements may have beneficial effects after human consumption and could potentially be recycled for animal nutrition in line with the circular economy concept.
ITALIAN JOURNAL OF ANIMAL SCIENCE
(2021)
Article
Agriculture, Multidisciplinary
Ruth T. Boachie, Ogadimma D. Okagu, Raliat Abioye, Nico Huttmann, Teresa Oliviero, Edoardo Capuano, Vincenzo Fogliano, Chibuike C. Udenigwe
Summary: This study investigated the interaction between lentil protein and tannic acid and its impact on in vitro pepsin digestion. The results showed that tannic acid induced protein aggregation and reduced protein digestibility. These findings highlight the importance of the interaction between tannic acid and protein in food digestion, as well as the implications for protein structure and properties.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Nutrition & Dietetics
Pablo Jimenez-Barrios, Laura Sanchez-Rivera, Daniel Martinez-Maqueda, Yann Le Gouar, Didier Dupont, Beatriz Miralles, Isidra Recio
Summary: It is known that casein hydrolysis accelerates gastrointestinal transit, but its effect on the composition of digests is not fully understood. This study aims to characterize duodenal digests from pigs fed with micellar casein and casein hydrolysate at the peptidome level. The digests from casein contained a wider range and more peptides compared to the hydrolysate. The peptide profile was different, with more opioid sequences found in the casein digests. Plasma amino acid levels were higher in animals fed with the hydrolysate at short times. Discriminant analysis tools were used to identify sequence differences between the substrates for future studies.
Article
Chemistry, Applied
Mengxue Fang, Juan You, Tao Yin, Yang Hu, Ru Liu, Hongying Du, Youming Liu, Shanbai Xiong
Summary: This study investigated the impact of cross-linking degree on the in vitro gastrointestinal digestion and absorption of surimi gel. Results showed that higher cross-linking degree promoted the release of peptides during gastrointestinal digestion. Additionally, dynamic digestion was found to be more thorough compared to static digestion, especially during gastric digestion.
Review
Environmental Sciences
Cesar Alvites, Marco Marchetti, Bruno Lasserre, Giovanni Santopuoli
Summary: This systematic literature review examines the applications of LiDAR systems in quantifying and classifying timber assortments. The results show a growing interest in using LiDAR systems for forest-related research, particularly in forest inventory and productivity. However, there is a lack of studies using spaceborne LiDAR systems for timber assortment assessments, mainly due to limitations in time and sample size. Terrestrial LiDAR systems perform better in characterizing understory trees. Combining airborne/UAS systems with terrestrial LiDAR systems holds promise for obtaining detailed data on timber assortments in large forest areas. Furthermore, there is a steady increase in interest among scientists in using machine learning and deep learning algorithms for LiDAR processes.
Article
Biochemistry & Molecular Biology
Yaqi Zhang, Yunfei Kong, Wanjun Xu, Zhen Yang, Yulong Bao
Summary: Irradiation affects the physicochemical properties and digestion behavior of chickpea protein, causing changes in protein solubility, oxidative modification, structural changes, and peptide characteristics.
Article
Chemistry, Multidisciplinary
Jiaming Peng, Gregory R. Hughes, Manuel M. Mueller, Florian P. Seebeck
Summary: S-adenosylmethionine-dependent methyltransferases play crucial roles in numerous biological processes. This report presents a novel approach utilizing enzyme-catalyzed F-methylation to activate carboxylate substrates for conjugation with nucleophiles under physiological conditions. This method shows potential for synthesizing small amides, hydroxamates, and thioesters, as well as for protein modification and chemical ligation.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Environmental Sciences
Amit Singh, Mohit Singh Rana, Harshit Tiwari, Manoj Kumar, Sarthak Saxena, Vishal Anand, Sanjeev Kumar Prajapati
Summary: Eutrophicated inland water bodies contribute to greenhouse gas emissions, but microalgae-based technology can combat eutrophication by using algal biomass for biofuel production, leading to a circular bioeconomy framework.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Food Science & Technology
Jorge Parodi, Hector Herrera, Rodrigo Sanchez, Brian Effer
Summary: This study proposes a proteolysis system to indirectly assess the quality of protein in salmonid diets. By using an artificial gastric solution and conducting experiments, the source and quality of protein can be evaluated, providing support for nutrition studies.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Forestry
Julia H. Olszewski, John D. Bailey
Summary: Fuel reduction treatments and ecosystem resilience restoration are crucial in forest management, especially in the face of high-intensity wildfire risks. This study used LiDAR data to assess changes in fuel structure after a large-scale forest restoration project, providing forest managers with a new option for evaluating treatment effectiveness.
Article
Biochemistry & Molecular Biology
Sandra Michel-Souzy, Naomi M. Hamelmann, Sara Zarzuela-Pura, Jos M. J. Paulusse, Jeroen J. L. M. Cornelissen
Summary: Encapsulin-based protein cages show potential for biomedical applications, with new surface modifications and improved production protocol for Thermotoga maritima and Brevibacterium linens encapsulins. Multimodification of Tm encapsulin allows up to 240 functionalities on the cage surface, enhancing potential for biomedical use. The study also reveals differences in stability of encapsulin variants based on tag insertion position, providing insights for further study in biomedical applications.
Review
Chemistry, Physical
Tatiana Porto Santos, Cesare M. Cejas, Rosiane Lopes Cunha
Summary: Microfluidic technology allows for control and observation of emulsion stability, as well as the behavior of droplets after formation, contributing to specific applications in food and pharmaceutical industries.
Article
Infectious Diseases
Hongmei Chen, Shanshan Li, Weijie Zhao, Jiaheng Deng, Zhuohong Yan, Tingting Zhang, Shuan Wen, Haiping Guo, Lei Li, Jianfeng Yuan, Hongtao Zhang, Liping Ma, Jianhua Zheng, Mengqiu Gao, Yu Pang
Summary: Using LC-MS/MS-based peptidomics, we have identified several potential new antigen biomarkers for the diagnosis of tuberculosis. These peptides show promising efficacy in terms of sensitivity and specificity.
INFECTION AND DRUG RESISTANCE
(2022)
Article
Food Science & Technology
Zuhaib F. Bhat, James D. Morton, Sunil Kumar, Hina F. Bhat, Rana Muhammad Aadil, Alaa El-Din A. Bekhit
Summary: This paper reviews the application of ultrasonication in the processing of animal derived foods, focusing on the effect of ultrasonication on the digestibility of different animal derived food matrices. The paper critically evaluates and discusses the underlying mechanisms and optimized conditions for improved protein digestibility. The review emphasizes the latest concepts and views on the ultrasonication process.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2022)
Article
Engineering, Environmental
Marcelle Martins, Samuel Lunardi, Vanessa de Andrade Puhl, Bruno Segalla Pizzolatti, Marcus Soares
Summary: Bank filtration for water treatment is limited by clogging, with fine sand resulting in more severe biological clogging and a significant reduction in hydraulic conductivity. Factors such as grain size distribution and hydrodynamic effects play a role in biological clogging during filtration processes.
JOURNAL OF WATER PROCESS ENGINEERING
(2021)
Article
Nutrition & Dietetics
Caroline Buffiere, Manon Hiolle, Marie-Agnes Peyron, Ruddy Richard, Nathalie Meunier, Cindy Batisse, Didier Remond, Didier Dupont, Francoise Nau, Bruno Pereira, Isabelle Savary-Auzeloux
Summary: The structure of food matrix affects the absorption of folate and other macronutrients, with pudding and sponge cake showing the highest folate availability while custard and biscuit showing the lowest. Analysis of plasma kinetics of other nutrients helps explain the lower bioavailability of folates in custard and biscuit.
EUROPEAN JOURNAL OF NUTRITION
(2021)
Article
Chemistry, Applied
B. Miralles, J. Sanchon, L. Sanchez-Rivera, D. Martinez-Maqueda, Y. Le Gouar, D. Dupont, L. Amigo, I. Recio
Summary: Correlation and validation between simulated and in vivo gastrointestinal digestion of food compounds is crucial. This study monitored the digestion of milk micellar casein in the porcine upper intestinal tract and found clear similarities between in vitro and in vivo generated peptide profiles, with the in vitro digestion model providing a similar peptide profile to that found in the porcine duodenum.
Article
Food Science & Technology
George Bazar, Hajnalka Hingyi, Eva Csavajda, Csaba Palko, Haruna Gado Yakubu, Carlos Pineda-Vadillo, Didier Dupont, Francesco Capozzi, Alessandra Bordoni, Tamas Toth
Summary: This study used electronic sensor array technology to test pancakes enriched with docosahexaenoic acid and anthocyanins. The results showed a strong relation between the number of days that samples were stored and the odor describing sensor signals of enriched samples. The electronic nose technology proved to be applicable in the characterization of bioactive-enriched foods and useful in monitoring odor alterations during storage.
FOOD ANALYTICAL METHODS
(2022)
Article
Chemistry, Applied
Amira Halabi, Thomas Croguennec, Olivia Menard, Valerie Briard-Bion, Julien Jardin, Yann Le Gouar, Marie Hennetier, Said Bouhallab, Didier Dupont, Amelie Deglaire
Summary: The impact of protein structure on the digestion of infant milk formulas is significant. The configuration of whey proteins and heating conditions affect the microstructure of digestion products and protein hydrolysis kinetics. Unheated formulas contain more numerous and resistant intestinal bioactive peptides, which are beneficial for infant health.
FOOD HYDROCOLLOIDS
(2022)
Article
Nutrition & Dietetics
Didier Dupont, Francoise Nau
Summary: Studying the mechanisms of food disintegration in the gastrointestinal tract provides insights into the impact of food on human health. The structure of food products plays a crucial role in the release and bioavailability of nutrients in the digestive system. This article explores how the structure of foods and their constituents affect digestion, highlighting the potential variations in data depending on the scale considered.
CAHIERS DE NUTRITION ET DE DIETETIQUE
(2022)
Article
Chemistry, Applied
Stefano Nebbia, Amelie Deglaire, Olivia Menard, Gwenaele Henry, Elettra Barberis, Marcello Manfredi, Enrico Bertino, Alessandra Coscia, Didier Dupont, Marzia Giribaldi, Laura Cavallarin
Summary: This study found that an experimental donkey milk-derived fortifier may be a better source of proteins and lipids for preterm infants compared to a commercial bovine milk-derived fortifier.
Article
Chemistry, Applied
Francoise Nau, Steven Le Feunteun, Yann Le Gouar, Gwenaele Henry, Maryvonne Pasco, Catherine Guerin-Dubiard, Kera Nyemb-Diop, Didier Dupont
Summary: There is a lack of understanding on how food structure affects food digestion, but a study on pigs revealed that the structure of egg white gels had an impact on gastric disintegration, pH levels, pepsin concentration, proteolysis, and amino acid absorption. The more acidic and soft gel resulted in earlier and more intense proteolysis and higher concentration of pepsin.
Article
Nutrition & Dietetics
Elise Charton, Alexandre Bourgeois, Amandine Bellanger, Yann Le-Gouar, Patrice Dahirel, Veronique Rome, Gwenaelle Randuineau, Armelle Cahu, Paul J. Moughan, Carlos A. Montoya, Sophie Blat, Didier Dupont, Amelie Deglaire, Isabelle Le Huerou-Luron
Summary: Early nutrition plays a crucial role in infant development and health, affecting the gut microbiota and its relationship with gut function and brain development. This study found that infant diet can modify the composition of gut microbiota and impact the microbiota-gut-brain axis. Piglets fed human milk showed increased intestinal permeability, altered immune activity and endocrine function, and changes in gene expression related to brain barrier, endocrine function, and fatty acid receptors.
FRONTIERS IN NUTRITION
(2022)
Article
Food Science & Technology
Jun Wang, Jordane Ossemond, Julien Jardin, Valerie Briard-Bion, Gwenaele Henry, Yann Le Gouar, Olivia Menard, Sebastien Le, Ashkan Madadlou, Didier Dupont, Frederique Pedrono
Summary: This study compared the bioavailability of encapsulated and unencapsulated DHA in a food matrix. The results showed that encapsulated DHA oil had smaller and more uniformly dispersed lipid droplets, higher hydrolysis rate, and released more free DHA. Encapsulation of DHA oil significantly improved its bioavailability.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Food Science & Technology
Stefano Nebbia, Olivia Menard, Marie-Francoise Cochet, Gwenaele Henry, Nathalie Daniel, Lorraine Moran, Kate Lennon, Grainne Dollard, Cian Moloney, Michelle Collins, Francois Morgan, Didier Dupont
Summary: Due to the lower efficiency of the elderly digestion system, new formulations are needed to increase the bioaccessibility of macronutrients. The study evaluated the effect of different protein sources production processes and lipid sources on the digestion of elderly formulas. The results showed a slight impact of the production process on proteolysis and a lesser extent of lipolysis when bovine cream was added to the formula.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Nutrition & Dietetics
Pablo Jimenez-Barrios, Laura Sanchez-Rivera, Daniel Martinez-Maqueda, Yann Le Gouar, Didier Dupont, Beatriz Miralles, Isidra Recio
Summary: It is known that casein hydrolysis accelerates gastrointestinal transit, but its effect on the composition of digests is not fully understood. This study aims to characterize duodenal digests from pigs fed with micellar casein and casein hydrolysate at the peptidome level. The digests from casein contained a wider range and more peptides compared to the hydrolysate. The peptide profile was different, with more opioid sequences found in the casein digests. Plasma amino acid levels were higher in animals fed with the hydrolysate at short times. Discriminant analysis tools were used to identify sequence differences between the substrates for future studies.
Article
Chemistry, Applied
Audrey Boulier, Sylvain Denis, Gwenaele Henry, Sylvie Guerin, Monique Alric, Nathalie Meunier, Adeline Blot, Bruno Pereira, Corinne Malpuech-Brugere, Didier Remond, Yves Boirie, Alain Baniel, Ruddy Richard, Didier Dupont, Gaelle Boudry
Summary: This study aimed to evaluate the impact of casein structure on its digestion and subsequent amino acid delivery. The results showed that sodium caseinate (SC), formed of small aggregates, had higher nitrogen levels after in vitro digestion compared to micellar casein (MC) and calcium caseinate (CC). In a randomized, double blind, cross-over study with healthy volunteers, the peak concentration of indispensable amino acids in plasma was higher after SC ingestion than after MC or CC ingestion. γ-scintigraphy using labelled meals in pigs revealed that SC was mainly localized in the proximal part of the stomach while MC was distributed in the entire gastric cavity. Caseins were found in both solid and liquid phases, and partly hydrolyzed shortly after SC drink ingestion. These findings support the concept of slow digestion for MC and rapid digestion for SC, likely due to their intra-gastric clotting properties.
Article
Food Science & Technology
Olivia Menard, Lucile Chauvet, Gwenaele Henry, Didier Dupont, Claire Gaudichon, Juliane Calvez, Amelie Deglaire
Summary: The present study aimed to determine the contribution of endogenous nitrogen to the protein digestibility values obtained in vitro. The results showed that endogenous nitrogen plays an important role in protein digestion, especially when digesting low protein solutions.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Food Science & Technology
Amelie Deglaire, Jeehyun Lee, Luca Lanotte, Thomas Croguennec, Cecile Le Floch-Fouere, Romain Jeantet, Nadia Berkova, Frederique Pedrono, Yves Le Loir, Didier Dupont, Genevieve Gesan-Guiziou, Sergine Even
Summary: The review explores the challenges and opportunities in optimizing infant formula (IF) to make it more biomimetic and sustainable. The study suggests that optimizing IF requires trade-offs between various objectives, such as mimicking human milk, ensuring safety, and considering sustainability issues. A multi-objective optimization strategy, involving collaboration across different disciplines, is proposed for rethinking IF production.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Anais Lavoisier, Martine Morzel, Severine Chevalier, Gwenaele Henry, Julien Jardin, Marielle Harel-Oger, Gilles Garric, Didier Dupont
Summary: This study investigated the digestion differences of high-protein dairy products in the elderly population. The results showed that the digestion rate in the gastric phase was slower in the older adult model, but no significant differences were observed in proteolysis in the intestinal phase compared to the young adult model.
