Regulation of Endoplasmic Reticulum–Mitochondria Ca2+ Transfer and Its Importance for Anti-Cancer Therapies
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Title
Regulation of Endoplasmic Reticulum–Mitochondria Ca2+ Transfer and Its Importance for Anti-Cancer Therapies
Authors
Keywords
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Journal
Frontiers in Oncology
Volume 7, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-08-31
DOI
10.3389/fonc.2017.00180
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Note: Only part of the references are listed.- Mitochondrial Ca 2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity
- (2017) Zhiwei Dong et al. MOLECULAR CELL
- BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation
- (2017) Angela Bononi et al. NATURE
- PTEN counteracts FBXL2 to promote IP3R3- and Ca2+-mediated apoptosis limiting tumour growth
- (2017) Shafi Kuchay et al. NATURE
- The metastatic suppressor NDRG1 inhibits EMT, migration and invasion through interaction and promotion of caveolin-1 ubiquitylation in human colorectal cancer cells
- (2017) L Mi et al. ONCOGENE
- Mipsagargin, a novel thapsigargin-based PSMA-activated prodrug: results of a first-in-man phase I clinical trial in patients with refractory, advanced or metastatic solid tumours
- (2016) D Mahalingam et al. BRITISH JOURNAL OF CANCER
- SKF-96365 activates cytoprotective autophagy to delay apoptosis in colorectal cancer cells through inhibition of the calcium/CaMKIIγ/AKT-mediated pathway
- (2016) Zhao Jing et al. CANCER LETTERS
- Mechanisms through Which Hypoxia-Induced Caveolin-1 Drives Tumorigenesis and Metastasis in Hepatocellular Carcinoma
- (2016) Xiaowen Mao et al. CANCER RESEARCH
- Resveratrol Specifically Kills Cancer Cells by a Devastating Increase in the Ca2+ Coupling Between the Greatly Tethered Endoplasmic Reticulum and Mitochondria
- (2016) Corina T. Madreiter-Sokolowski et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- ABT737 reverses cisplatin resistance by regulating ER-mitochondria Ca2+ signal transduction in human ovarian cancer cells
- (2016) Qi Xie et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Stromal interaction molecule 1 plays an important role in gastric cancer progression
- (2016) JIN-MEI XU et al. ONCOLOGY REPORTS
- PML at Mitochondria-Associated Membranes Is Critical for the Repression of Autophagy and Cancer Development
- (2016) Sonia Missiroli et al. Cell Reports
- Calcium signaling as a mediator of cell energy demand and a trigger to cell death
- (2015) Gauri Bhosale et al. Annals of the New York Academy of Sciences
- Mitochondria-Associated Membranes: Composition, Molecular Mechanisms, and Physiopathological Implications
- (2015) Carlotta Giorgi et al. ANTIOXIDANTS & REDOX SIGNALING
- A novel chimeric aequorin fused with caveolin-1 reveals a sphingosine kinase 1-regulated Ca2+ microdomain in the caveolar compartment
- (2015) Ilari Pulli et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Inside the tumor: p53 modulates calcium homeostasis
- (2015) Carlotta Giorgi et al. CELL CYCLE
- Erratum: The SR/ER-mitochondria calcium crosstalk is regulated by GSK3β during reperfusion injury
- (2015) L Gomez et al. CELL DEATH AND DIFFERENTIATION
- Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury
- (2015) Giampaolo Morciano et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Motifs of VDAC2 required for mitochondrial Bak import and tBid-induced apoptosis
- (2015) Shamim Naghdi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner
- (2015) Carlotta Giorgi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting thapsigargin towards tumors
- (2015) Nhu Thi Quynh Doan et al. STEROIDS
- Synergistic killing of human small cell lung cancer cells by the Bcl-2-inositol 1,4,5-trisphosphate receptor disruptor BIRD-2 and the BH3-mimetic ABT-263
- (2015) E F Greenberg et al. Cell Death & Disease
- A synthetic peptide targeting the BH4 domain of Bcl-2 induces apoptosis in multiple myeloma and follicular lymphoma cells alone or in combination with agents targeting the BH3-binding pocket of Bcl-2
- (2015) Andrew R. Lavik et al. Oncotarget
- Ras and autophagy in cancer development and therapy.
- (2015) Eran Schmukler et al. Oncotarget
- Elevated Orai1 expression mediates tumor-promoting intracellular Ca2+ oscillations in human esophageal squamous cell carcinoma
- (2015) Hua Zhu et al. Oncotarget
- Dual Role of JNK1-mediated phosphorylation of Bcl-2 in autophagy and apoptosis regulation
- (2014) Yongjie Wei et al. Autophagy
- Oncogenic K-Ras suppresses IP3-dependent Ca2+ release through remodelling of the isoform composition of IP3Rs and ER luminal Ca2+ levels in colorectal cancer cell lines
- (2014) C. Pierro et al. JOURNAL OF CELL SCIENCE
- A polarized Ca2+, diacylglycerol and STIM1 signalling system regulates directed cell migration
- (2014) Feng-Chiao Tsai et al. NATURE CELL BIOLOGY
- Activation of a promyelocytic leukemia–tumor protein 53 axis underlies acute promyelocytic leukemia cure
- (2014) Julien Ablain et al. NATURE MEDICINE
- Inverse regulation of melanoma growth and migration by Orai1/STIM2-dependent calcium entry
- (2014) Hedwig Stanisz et al. Pigment Cell & Melanoma Research
- MicroRNAs in cancer: biomarkers, functions and therapy
- (2014) Josie Hayes et al. TRENDS IN MOLECULAR MEDICINE
- Identification of ML-9 as a lysosomotropic agent targeting autophagy and cell death
- (2014) A Kondratskyi et al. Cell Death & Disease
- SBF-1 exerts strong anticervical cancer effect through inducing endoplasmic reticulum stress-associated cell death via targeting sarco/endoplasmic reticulum Ca2+-ATPase 2
- (2014) W Li et al. Cell Death & Disease
- Identification of PTEN at the ER and MAMs and its regulation of Ca2+ signaling and apoptosis in a protein phosphatase-dependent manner
- (2013) A Bononi et al. CELL DEATH AND DIFFERENTIATION
- Tunicamycin Potentiates Cisplatin Anticancer Efficacy through the DPAGT1/Akt/ABCG2 Pathway in Mouse Xenograft Models of Human Hepatocellular Carcinoma
- (2013) H. Hou et al. MOLECULAR CANCER THERAPEUTICS
- The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter
- (2013) Xin Pan et al. NATURE CELL BIOLOGY
- Subcellular calcium measurements in mammalian cells using jellyfish photoprotein aequorin-based probes
- (2013) Massimo Bonora et al. Nature Protocols
- H-Ras-driven tumoral maintenance is sustained through caveolin-1-dependent alterations in calcium signaling
- (2013) A Rimessi et al. ONCOGENE
- STIM1 and Orai1 mediate CRAC channel activity and are essential for human glioblastoma invasion
- (2013) Rajender K. Motiani et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Phosphorylated K-Ras limits cell survival by blocking Bcl-xL sensitization of inositol trisphosphate receptors
- (2013) P. J. Sung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ca2+ release-activated Ca2+ channel blockade as a potential tool in antipancreatitis therapy
- (2013) J. V. Gerasimenko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Purinergic signalling and cancer
- (2013) Geoffrey Burnstock et al. Purinergic Signalling
- IP3R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP3R-derived peptide targeting the BH4 domain of Bcl-2
- (2013) H Akl et al. Cell Death & Disease
- STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry
- (2013) Peter B. Stathopulos et al. Nature Communications
- Heat-shock proteins attenuate SERCA inactivation by the anti-apoptotic protein Bcl-2: possible implications for the ER Ca2+-mediated apoptosis
- (2012) Elena S. Dremina et al. BIOCHEMICAL JOURNAL
- Downregulation of the Mitochondrial Calcium Uniporter by Cancer-Related miR-25
- (2012) Saverio Marchi et al. CURRENT BIOLOGY
- Role of Molecular Determinants of Store-operated Ca2+Entry (Orai1, Phospholipase A2 Group 6, and STIM1) in Focal Adhesion Formation and Cell Migration
- (2012) Claudia Schäfer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Endoplasmic reticulum–mitochondria contacts: function of the junction
- (2012) Ashley A. Rowland et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Ero1α Regulates Ca2+ Fluxes at the Endoplasmic Reticulum–Mitochondria Interface (MAM)
- (2011) Tiziana Anelli et al. ANTIOXIDANTS & REDOX SIGNALING
- Urban planning of the endoplasmic reticulum (ER): How diverse mechanisms segregate the many functions of the ER
- (2011) Emily M. Lynes et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria
- (2011) D De Stefani et al. CELL DEATH AND DIFFERENTIATION
- Genetic and Pharmacologic Inhibition of the Ca2+ Influx Channel TRPC3 Protects Secretory Epithelia From Ca2+-Dependent Toxicity
- (2011) Min Seuk Kim et al. GASTROENTEROLOGY
- The C Terminus of Bax Inhibitor-1 Forms a Ca2+-permeable Channel Pore
- (2011) Geert Bultynck et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
- (2011) Joshua M. Baughman et al. NATURE
- A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
- (2011) Diego De Stefani et al. NATURE
- Calcium store sensor stromal-interaction molecule 1-dependent signaling plays an important role in cervical cancer growth, migration, and angiogenesis
- (2011) Y.-F. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Local Ca2+ Entry Via Orai1 Regulates Plasma Membrane Recruitment of TRPC1 and Controls Cytosolic Ca2+ Signals Required for Specific Cell Functions
- (2011) Kwong Tai Cheng et al. PLOS BIOLOGY
- Redox Control of Protein Kinase C: Cell- and Disease-Specific Aspects
- (2010) Carlotta Giorgi et al. ANTIOXIDANTS & REDOX SIGNALING
- Induction of Ca2+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interaction
- (2010) F. Zhong et al. BLOOD
- PML Regulates Apoptosis at Endoplasmic Reticulum by Modulating Calcium Release
- (2010) C. Giorgi et al. SCIENCE
- Orai1 and STIM1 Are Critical for Breast Tumor Cell Migration and Metastasis
- (2009) Shengyu Yang et al. CANCER CELL
- Native Store-operated Ca2+Influx Requires the Channel Function of Orai1 and TRPC1
- (2009) Min Seuk Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor
- (2009) Y.-P. Rong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intramitochondrial calcium regulation by the FHIT gene product sensitizes to apoptosis
- (2009) A. Rimessi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Akt kinase reducing endoplasmic reticulum Ca2+ release protects cells from Ca2+-dependent apoptotic stimuli
- (2008) Saverio Marchi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The versatility of mitochondrial calcium signals: From stimulation of cell metabolism to induction of cell death
- (2008) Alessandro Rimessi et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- The Bax Inhibitor-1 (BI-1) Family in Apoptosis and Tumorigenesis
- (2008) Kerstin Reimers et al. CURRENT MOLECULAR MEDICINE
- Molecular Mechanisms and Pathophysiology of Necrotic Cell Death
- (2008) Nele Vanlangenakker et al. CURRENT MOLECULAR MEDICINE
- Ca2+-store-dependent and -independent reversal of Stim1 localization and function
- (2008) J. T. Smyth et al. JOURNAL OF CELL SCIENCE
- Targeting Bcl-2-IP3 Receptor Interaction to Reverse Bcl-2's Inhibition of Apoptotic Calcium Signals
- (2008) Yi-Ping Rong et al. MOLECULAR CELL
- Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis
- (2008) T. Szado et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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