Aurora-A promotes the establishment of spindle assembly checkpoint by priming the Haspin-Aurora-B feedback loop in late G2 phase

Aurora A Kinase Contributes to a Pole-Based Error Correction Pathway

(2015) Anna A. Ye et al.   CURRENT BIOLOGY

Spatial Regulation of Kinetochore Microtubule Attachments by Destabilization at Spindle Poles in Meiosis I

(2015) Lukáš Chmátal et al.   CURRENT BIOLOGY

Spatial Compartmentalization Specializes the Function of Aurora A and Aurora B

(2015) Si Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Safety and activity of alisertib, an investigational aurora kinase A inhibitor, in patients with breast cancer, small-cell lung cancer, non-small-cell lung cancer, head and neck squamous-cell carcinoma, and gastro-oesophageal adenocarcinoma: a five-arm phase 2 study

(2015) Bohuslav Melichar et al.   LANCET ONCOLOGY

MLN8054 and Alisertib (MLN8237): Discovery of Selective Oral Aurora A Inhibitors

(2015) Todd B. Sells et al.   ACS Medicinal Chemistry Letters

Natural Loss of Mps1 Kinase in Nematodes Uncovers a Role for Polo-like Kinase 1 in Spindle Checkpoint Initiation

(2015) Julien Espeut et al.   Cell Reports

Plk1 and Mps1 Cooperatively Regulate the Spindle Assembly Checkpoint in Human Cells

(2015) Conrad von Schubert et al.   Cell Reports

Nuclear Pores Protect Genome Integrity by Assembling a Premitotic and Mad1-Dependent Anaphase Inhibitor

(2014) Veronica Rodriguez-Bravo et al.   CELL

Cdk1 Inactivation Terminates Mitotic Checkpoint Surveillance and Stabilizes Kinetochore Attachments in Anaphase

(2014) María Dolores Vázquez-Novelle et al.   CURRENT BIOLOGY

Cell division: control of the chromosomal passenger complex in time and space

(2013) Armando van der Horst et al.   CHROMOSOMA

Drosophila Polo regulates the spindle assembly checkpoint through Mps1-dependent BubR1 phosphorylation

(2013) Carlos Conde et al.   EMBO JOURNAL

Bora and Aurora-A continue to activate Plk1 in mitosis

(2013) Wytse Bruinsma et al.   JOURNAL OF CELL SCIENCE

Autoinhibition and Polo-Dependent Multisite Phosphorylation Restrict Activity of the Histone H3 Kinase Haspin to Mitosis

(2013) Cristina Ghenoiu et al.   MOLECULAR CELL

Aurora Kinase-A Inactivates DNA Damage-Induced Apoptosis and Spindle Assembly Checkpoint Response Functions of p73

(2012) Hiroshi Katayama et al.   CANCER CELL

Aurora A kinase (AURKA) in normal and pathological cell division

(2012) Anna S. Nikonova et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mps1 promotes rapid centromere accumulation of Aurora B

(2012) Maike S van der Waal et al.   EMBO REPORTS

The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis

(2012) Mar Carmena et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Chromosomal Passenger Complex Activates Polo Kinase at Centromeres

(2012) Mar Carmena et al.   PLOS BIOLOGY

The inhibition of Aurora A abrogates the mitotic delay induced by microtubule perturbing agents

(2011) Deborah R. Wysong et al.   CELL CYCLE

Characterization of Alisertib (MLN8237), an Investigational Small-Molecule Inhibitor of Aurora A Kinase Using Novel In Vivo Pharmacodynamic Assays

(2011) M. G. Manfredi et al.   CLINICAL CANCER RESEARCH

PP1/Repo-Man Dephosphorylates Mitotic Histone H3 at T3 and Regulates Chromosomal Aurora B Targeting

(2011) Junbin Qian et al.   CURRENT BIOLOGY

Feedback Control in Sensing Chromosome Biorientation by the Aurora B Kinase

(2011) Kevan J. Salimian et al.   CURRENT BIOLOGY

A Positive Feedback Loop Involving Haspin and Aurora B Promotes CPC Accumulation at Centromeres in Mitosis

(2011) Fangwei Wang et al.   CURRENT BIOLOGY

Aurora A and Aurora B jointly coordinate chromosome segregation and anaphase microtubule dynamics

(2011) Nadia Hégarat et al.   JOURNAL OF CELL BIOLOGY

Cdk1-phosphorylated CUEDC2 promotes spindle checkpoint inactivation and chromosomal instability

(2011) Yan-Fei Gao et al.   NATURE CELL BIOLOGY

Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis

(2011) Adrian T. Saurin et al.   Nature Communications

Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E

(2010) Yumi Kim et al.   CELL

Two Histone Marks Establish the Inner Centromere and Chromosome Bi-Orientation

(2010) Yuya Yamagishi et al.   SCIENCE

Survivin Reads Phosphorylated Histone H3 Threonine 3 to Activate the Mitotic Kinase Aurora B

(2010) Alexander E. Kelly et al.   SCIENCE

Histone H3 Thr-3 Phosphorylation by Haspin Positions Aurora B at Centromeres in Mitosis

(2010) Fangwei Wang et al.   SCIENCE

Aurora B kinase activation requires survivin priming phosphorylation by PLK1

(2010) Youjun Chu et al.   Journal of Molecular Cell Biology

Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins

(2009) Mar Carmena et al.   CURRENT OPINION IN CELL BIOLOGY

The decision to enter mitosis: feedback and redundancy in the mitotic entry network

(2009) Arne Lindqvist et al.   JOURNAL OF CELL BIOLOGY

Determinants for the efficiency of anticancer drugs targeting either Aurora-A or Aurora-B kinases in human colon carcinoma cells

(2009) P. Kaestner et al.   MOLECULAR CANCER THERAPEUTICS

Oncogenic role of nuclear accumulated Aurora-A

(2009) Masaaki Tatsuka et al.   MOLECULAR CARCINOGENESIS

Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis

(2009) Andrew J. Holland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Sensing Chromosome Bi-Orientation by Spatial Separation of Aurora B Kinase from Kinetochore Substrates

(2009) D. Liu et al.   SCIENCE

Plk1 regulates mitotic Aurora A function through βTrCP-dependent degradation of hBora

(2008) Eunice H. Y. Chan et al.   CHROMOSOMA

Aurora-A Kinase Is Essential for Bipolar Spindle Formation and Early Development

(2008) D. O. Cowley et al.   MOLECULAR AND CELLULAR BIOLOGY

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery

(2008) Libor Macůrek et al.   NATURE

Bora and the Kinase Aurora A Cooperatively Activate the Kinase Plk1 and Control Mitotic Entry

(2008) A. Seki et al.   SCIENCE