Pathogenesis and Therapeutic Mechanisms in Immune Thrombocytopenia (ITP)
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Title
Pathogenesis and Therapeutic Mechanisms in Immune Thrombocytopenia (ITP)
Authors
Keywords
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Journal
Journal of Clinical Medicine
Volume 6, Issue 2, Pages 16
Publisher
MDPI AG
Online
2017-02-10
DOI
10.3390/jcm6020016
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Note: Only part of the references are listed.- Rituximab in immune thrombocytopenia: gender, age, and response as predictors of long-term response
- (2017) Miriam Marangon et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Gender and duration of disease differentiate responses to rituximab-dexamethasone therapy in adults with immune thrombocytopenia
- (2016) John Chapin et al. AMERICAN JOURNAL OF HEMATOLOGY
- Health-related quality of life and burden of fatigue in patients with primary immune thrombocytopenia by phase of disease
- (2016) Fabio Efficace et al. AMERICAN JOURNAL OF HEMATOLOGY
- Bone marrow niche in immune thrombocytopenia: a focus on megakaryopoiesis
- (2016) Elaheh Khodadi et al. ANNALS OF HEMATOLOGY
- Procoagulant profile in patients with immune thrombocytopenia
- (2016) María T. Álvarez-Román et al. BRITISH JOURNAL OF HAEMATOLOGY
- Abnormal Distribution and Function of Monocyte Subsets in Patients With Primary Immune Thrombocytopenia
- (2016) Yanhui Yang et al. CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
- Long-term results of splenectomy in adult chronic immune thrombocytopenia
- (2016) Yue Guan et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Investigation of platelet apoptosis in adult patients with chronic immune thrombocytopenia
- (2016) Gang Deng et al. Hematology
- Advances in the pathophysiology of primary immune thrombocytopenia
- (2016) María Perera et al. Hematology
- Rituximab salvage therapy in adults with immune thrombocytopenia: retrospective study on efficacy and safety profiles
- (2016) Emilie Reboursiere et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Altered dendritic cell functions in autoimmune diseases: distinct and overlapping profiles
- (2016) Frédéric Coutant et al. Nature Reviews Rheumatology
- Mechanistic properties of intravenous immunoglobulin in murine immune thrombocytopenia: support for FcγRIIB falls by the wayside
- (2016) Andrew R. Crow et al. SEMINARS IN HEMATOLOGY
- The nonhemostatic immune functions of platelets
- (2016) Rick Kapur et al. SEMINARS IN HEMATOLOGY
- Antigen-Presenting Cells and Antigen Presentation in Tertiary Lymphoid Organs
- (2016) Catherine E. Hughes et al. Frontiers in Immunology
- CD8+ T cells induce platelet clearance in the liver via platelet desialylation in immune thrombocytopenia
- (2016) Jihua Qiu et al. Scientific Reports
- Current Management of Primary Immune Thrombocytopenia
- (2015) Drew Provan et al. ADVANCES IN THERAPY
- CD20+ B-cell depletion therapy suppresses murine CD8+ T-cell-mediated immune thrombocytopenia
- (2015) L. Guo et al. BLOOD
- Fatigue in immune thrombocytopenia
- (2015) Quentin A. Hill et al. BRITISH JOURNAL OF HAEMATOLOGY
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- (2015) Adrian Newland et al. BRITISH JOURNAL OF HAEMATOLOGY
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- (2015) Laurent Gilardin et al. CANADIAN MEDICAL ASSOCIATION JOURNAL
- The secret life of a megakaryocyte: emerging roles in bone marrow homeostasis control
- (2015) Alessandro Malara et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Flow cytometric measurement of platelet-associated immunoglobulin in children with newly diagnosed Immune Thrombocytopenia
- (2015) Ole Haubjerg Nielsen et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Immune thrombocytopenia: antiplatelet autoantibodies inhibit proplatelet formation by megakaryocytes and impair platelet production in vitro
- (2015) M. Iraqi et al. HAEMATOLOGICA
- CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow
- (2015) Ayako Nakamura-Ishizu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Nouvelle Cuisine: Platelets Served with Inflammation
- (2015) Rick Kapur et al. JOURNAL OF IMMUNOLOGY
- Rituximab as second-line treatment for adult immune thrombocytopenia (the RITP trial): a multicentre, randomised, double-blind, placebo-controlled trial
- (2015) Waleed Ghanima et al. LANCET
- Can Immune Thrombocytopenia Be Cured with Medical Therapy?
- (2015) Eline Prak et al. SEMINARS IN THROMBOSIS AND HEMOSTASIS
- Immune thrombocytopenia: antiplatelet autoantibodies inhibit proplatelet formation by megakaryocytes and impair platelet production in vitro
- (2015) M. Iraqi et al. HAEMATOLOGICA
- Immunomodulation by IVIg and the Role of Fc-Gamma Receptors: Classic Mechanisms of Action after all?
- (2015) Sietse Q. Nagelkerke et al. Frontiers in Immunology
- The defective bone marrow-derived mesenchymal stem cells in patients with chronic immune thrombocytopenia
- (2014) Donglei Zhang et al. AUTOIMMUNITY
- Association between an Impaired Bone Marrow Vascular Microenvironment and Prolonged Isolated Thrombocytopenia after Allogeneic Hematopoietic Stem Cell Transplantation
- (2014) Yuan Kong et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- C-reactive protein enhances IgG-mediated phagocyte responses and thrombocytopenia
- (2014) R. Kapur et al. BLOOD
- Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation
- (2014) Kellie R. Machlus et al. BRITISH JOURNAL OF HAEMATOLOGY
- Alterations in immune cell subsets and their cytokine secretion profile in childhood idiopathic thrombocytopenic purpura (ITP)
- (2014) R. M. Talaat et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
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- (2014) J. B. Bussel et al. HAEMATOLOGICA
- Health-related quality of life in children with newly diagnosed immune thrombocytopenia
- (2014) K. M. J. Heitink-Polle et al. HAEMATOLOGICA
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- (2014) Ingmar Bruns et al. NATURE MEDICINE
- Pathogenesis of immune thrombocytopenia
- (2014) Douglas B. Cines et al. PRESSE MEDICALE
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- (2013) David Grimaldi et al. ANNALS OF HEMATOLOGY
- The life of regulatory T cells
- (2013) Iris K. Gratz et al. Annals of the New York Academy of Sciences
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- (2012) C. Daridon et al. BLOOD
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- Outcomes 5 years after response to rituximab therapy in children and adults with immune thrombocytopenia
- (2012) V. L. Patel et al. BLOOD
- CD16+ monocytes control T-cell subset development in immune thrombocytopenia
- (2012) H. Zhong et al. BLOOD
- Defective regulatory B-cell compartment in patients with immune thrombocytopenia
- (2012) X. Li et al. BLOOD
- Risk of arterial thrombosis in patients with primary chronic immune thrombocytopenia: a Danish population-based cohort study
- (2012) Mette Nørgaard et al. BRITISH JOURNAL OF HAEMATOLOGY
- Short- and long-term risks of splenectomy for benign haematological disorders: should we revisit the indications?
- (2012) Francesco Rodeghiero et al. BRITISH JOURNAL OF HAEMATOLOGY
- Overexpression of RORγt under control of the CD2 promoter induces polyclonal plasmacytosis and autoantibody production in transgenic mice
- (2012) Keigyou Yoh et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The clinical significance of circulating B cells secreting anti-glycoprotein IIb/IIIa antibody and platelet glycoprotein IIb/IIIa in patients with primary immune thrombocytopenia
- (2012) Jian-fang Chen et al. Hematology
- Elevated profiles of Th22 cells and correlations with Th17 cells in patients with immune thrombocytopenia
- (2012) Yu Hu et al. HUMAN IMMUNOLOGY
- Effects of High-Dose Dexamethasone on Regulating Interleukin-22 Production and Correcting Th1 and Th22 Polarization in Immune Thrombocytopenia
- (2012) Jiang Cao et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Decreased plasma cytokines are associated with low platelet counts in aplastic anemia and immune thrombocytopenic purpura
- (2012) X. FENG et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
- The Ratio of Treg/Th17 Cells Correlates with the Disease Activity of Primary Immune Thrombocytopenia
- (2012) Lili Ji et al. PLoS One
- Immune Thrombocytopenia: Pathophysiologic and Clinical Update
- (2012) Roberto Stasi SEMINARS IN THROMBOSIS AND HEMOSTASIS
- Dendritic cells a double-edge sword in autoimmune responses
- (2012) Giada Amodio et al. Frontiers in Immunology
- Increased number of B-cells in the red pulp of the spleen in ITP
- (2011) Bob Olsson et al. ANNALS OF HEMATOLOGY
- Immunologic effects of rituximab on the human spleen in immune thrombocytopenia
- (2011) S. Audia et al. BLOOD
- The American Society of Hematology 2011 evidence-based practice guideline for immune thrombocytopenia
- (2011) C. Neunert et al. BLOOD
- Elevated plasma IL-22 levels correlated with Th1 and Th22 cells in patients with immune thrombocytopenia
- (2011) Jiang Cao et al. CLINICAL IMMUNOLOGY
- Fatigue in adult patients with primary immune thrombocytopenia
- (2011) Julia L. Newton et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Circulating plasmacytoid dendritic cells in patients with primary and Helicobacter pylori-associated immune thrombocytopenia
- (2011) Akio Saito et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Circulating CD4+CD161+CD196+ Th17 cells are not increased in immune thrombocytopenia
- (2011) D. Sollazzo et al. HAEMATOLOGICA
- Immune thrombocytopenia in children and adults: what's the same, what's different?
- (2011) H. Schulze et al. HAEMATOLOGICA
- The levels of IL-17A and of the cytokines involved in Th17 cell commitment are increased in patients with chronic immune thrombocytopenia
- (2011) A. M. C. Rocha et al. HAEMATOLOGICA
- Role of CD4+CD25+ T Cells in Children With Idiopathic Thrombocytopenic Purpura
- (2011) Laila El-Morsi Aboul-Fotoh et al. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
- Pathway of Toll-Like Receptor 7/B Cell Activating Factor/B Cell Activating Factor Receptor Plays a Role in Immune Thrombocytopenia In Vivo
- (2011) Qing Yang et al. PLoS One
- Increased Number of Tc17 and Correlation with Th17 Cells in Patients with Immune Thrombocytopenia
- (2011) Yu Hu et al. PLoS One
- Mechanisms of platelet recovery in ITP associated with therapy
- (2010) Sophie J. Y. Pang et al. ANNALS OF HEMATOLOGY
- Megakaryocytes constitute a functional component of a plasma cell niche in the bone marrow
- (2010) O. Winter et al. BLOOD
- Dexamethasone plus rituximab yields higher sustained response rates than dexamethasone monotherapy in adults with primary immune thrombocytopenia
- (2010) F. Zaja et al. BLOOD
- Improved regulatory T-cell activity in patients with chronic immune thrombocytopenia treated with thrombopoietic agents
- (2010) W. Bao et al. BLOOD
- Thrombopoietic agents
- (2010) Roberto Stasi et al. BLOOD REVIEWS
- Risk of venous thromboembolism in patients with primary chronic immune thrombocytopenia: a Danish population-based cohort study
- (2010) Marianne T. Severinsen et al. BRITISH JOURNAL OF HAEMATOLOGY
- Recent progress in understanding the pathogenesis of immune thrombocytopenia
- (2010) John W Semple et al. CURRENT OPINION IN HEMATOLOGY
- TLR7 regulates dendritic cell-dependent B-cell responses through BlyS in immune thrombocytopenic purpura
- (2010) Huiming Yu et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Thromboembolic events among adult patients with primary immune thrombocytopenia in the United Kingdom General Practice Research Database
- (2010) A. Sarpatwari et al. HAEMATOLOGICA
- Low-dose rituximab combined with short-term glucocorticoids up-regulates Treg cell levels in patients with immune thrombocytopenia
- (2010) Zhenyu Li et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Overview of the immune response
- (2010) David D. Chaplin JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Regulatory T-cells in systemic lupus erythematosus-associated thrombocytopenia: a comparison with idiopathic thrombocytopenic purpura
- (2010) S.-H. Park et al. LUPUS
- Association of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with idiopathic thrombocytopenic purpura in a Chinese population
- (2010) Huiyuan Li et al. PLATELETS
- The incidence of immune thrombocytopenic purpura in children and adults: A critical review of published reports
- (2009) Deirdra R. Terrell et al. AMERICAN JOURNAL OF HEMATOLOGY
- Surveillance of Antigen-Presenting Cells by CD4+CD25+ Regulatory T Cells in Autoimmunity
- (2009) Sébastien André et al. AMERICAN JOURNAL OF PATHOLOGY
- A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell-mediated responses that are differentially sensitive to therapy
- (2009) L. Chow et al. BLOOD
- International consensus report on the investigation and management of primary immune thrombocytopenia
- (2009) D. Provan et al. BLOOD
- The ITP syndrome: pathogenic and clinical diversity
- (2009) D. B. Cines et al. BLOOD
- Pathogenesis of chronic immune thrombocytopenia: increased platelet destruction and/or decreased platelet production
- (2009) Diane Nugent et al. BRITISH JOURNAL OF HAEMATOLOGY
- The role of Th17 cells in adult patients with chronic idiopathic thrombocytopenic purpura
- (2009) Zhen Xing Guo et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Elevated profile of Th17, Th1 and Tc1 cells in patients with immune thrombocytopenic purpura
- (2009) J. Zhang et al. HAEMATOLOGICA
- Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling
- (2009) Stefanie Eyerich et al. JOURNAL OF CLINICAL INVESTIGATION
- Profile of Th17 cytokines (IL-17, TGF-β, IL-6) and Th1 cytokine (IFN-γ) in patients with immune thrombocytopenic purpura
- (2008) Daoxin Ma et al. ANNALS OF HEMATOLOGY
- Role of molecular mimicry of hepatitis C virus protein with platelet GPIIIa in hepatitis C-related immunologic thrombocytopenia
- (2008) W. Zhang et al. BLOOD
- De novo induction of platelet-specific CD4+CD25+ regulatory T cells from CD4+CD25- cells in patients with idiopathic thrombocytopenic purpura
- (2008) X.-L. Zhang et al. BLOOD
- Analysis of regulatory T-cell changes in patients with idiopathic thrombocytopenic purpura receiving B cell-depleting therapy with rituximab
- (2008) R. Stasi et al. BLOOD
- Recruitment of T cells into bone marrow of ITP patients possibly due to elevated expression of VLA-4 and CX3CR1
- (2008) B. Olsson et al. BLOOD
- Defective circulating CD25 regulatory T cells in patients with chronic immune thrombocytopenic purpura
- (2008) J. Yu et al. BLOOD
- Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group
- (2008) F. Rodeghiero et al. BLOOD
- Improved quality of life for romiplostim-treated patients with chronic immune thrombocytopenic purpura: results from two randomized, placebo-controlled trials
- (2008) James N. George et al. BRITISH JOURNAL OF HAEMATOLOGY
- Increased cytotoxic T-lymphocyte-mediated cytotoxicity predominant in patients with idiopathic thrombocytopenic purpura without platelet autoantibodies
- (2008) C. Zhao et al. HAEMATOLOGICA
- Identification of a receptor required for the anti-inflammatory activity of IVIG
- (2008) R. M. Anthony et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Mechanisms of Action of Intravenous Immunoglobulin and Polyclonal Anti-D Immunoglobulin in the Amelioration of Immune Thrombocytopenic Purpura: What Do We Really Know?
- (2008) Andrew R. Crow et al. TRANSFUSION MEDICINE REVIEWS
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