Oxidative Stress in COPD: Sources, Markers, and Potential Mechanisms

The effect of phosphatidylinositol-3 kinase inhibition on matrix metalloproteinase-9 and reactive oxygen species release from chronic obstructive pulmonary disease neutrophils

(2016) V. Gupta et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The MIF Antagonist ISO-1 Attenuates Corticosteroid-Insensitive Inflammation and Airways Hyperresponsiveness in an Ozone-Induced Model of COPD

(2016) Kirsty E. Russell et al.   PLoS One

Local and Systemic Oxidative Stress and Glucocorticoid Receptor Levels in Chronic Obstructive Pulmonary Disease Patients

(2016) Mian Zeng et al.   Canadian Respiratory Journal

Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease

(2015) Coen H. Wiegman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

NADPH oxidases: an overview from structure to innate immunity-associated pathologies

(2014) Arvind Panday et al.   Cellular & Molecular Immunology

ROSics: Chemistry and proteomics of cysteine modifications in redox biology

(2014) Hee-Jung Kim et al.   MASS SPECTROMETRY REVIEWS

Twice daily N-acetylcysteine 600 mg for exacerbations of chronic obstructive pulmonary disease (PANTHEON): a randomised, double-blind placebo-controlled trial

(2014) Jin-Ping Zheng et al.   Lancet Respiratory Medicine

Mitochondrial fragmentation in cigarette smoke-induced bronchial epithelial cell senescence

(2013) Hiromichi Hara et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence

(2013) E. Sapey et al.   BLOOD

Analysis of Sputum Markers in the Evaluation of Lung Inflammation and Functional Impairment in Symptomatic Smokers and COPD Patients

(2013) Gregorino Paone et al.   DISEASE MARKERS

Aberrant neutrophil functions in stable chronic obstructive pulmonary disease: The neutrophil as an immunotherapeutic target

(2013) James A. Stockley et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Altered oxidant-antioxidant levels in the disease prognosis of chronic obstructive pulmonary disease

(2013) A. Ahmad et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

Measuring the Global Burden of Disease

(2013) Christopher J.L. Murray et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effects of N-Acetylcysteine in Ozone-Induced Chronic Obstructive Pulmonary Disease Model

(2013) Feng Li et al.   PLoS One

Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells

(2013) Roland F Hoffmann et al.   RESPIRATORY RESEARCH

Variability of sputum inflammatory mediators in COPD and α1-antitrypsin deficiency

(2012) Helen Stone et al.   EUROPEAN RESPIRATORY JOURNAL

Bronchiolar epithelial catalase is diminished in smokers with mild COPD

(2012) Tomoko Betsuyaku et al.   EUROPEAN RESPIRATORY JOURNAL

Quantitative evaluation of the role of cysteine and methionine residues in the antioxidant activity of human serum albumin using recombinant mutants

(2012) Yasunori Iwao et al.   IUBMB LIFE

Oxidative Stress in COPD Patients, Smokers and Non-Smokers Subjects

(2012) Heidar Tavilani et al.   Respiratory Care

Behavioral and Structural Differences in Migrating Peripheral Neutrophils from Patients with Chronic Obstructive Pulmonary Disease

(2011) Elizabeth Sapey et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Pharmacological antioxidant strategies as therapeutic interventions for COPD

(2011) Irfan Rahman   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Rac regulates PtdInsP3 signaling and the chemotactic compass through a redox-mediated feedback loop

(2011) J. W. P. Kuiper et al.   BLOOD

Nrf2 expression modifies influenza A entry and replication in nasal epithelial cells

(2011) Matthew J. Kesic et al.   FREE RADICAL BIOLOGY AND MEDICINE

Malondialdehyde in Exhaled Breath Condensate as a Marker of Oxidative Stress in Different Pulmonary Diseases

(2011) M. L. Bartoli et al.   MEDIATORS OF INFLAMMATION

Targeting Nrf2 Signaling Improves Bacterial Clearance by Alveolar Macrophages in Patients with COPD and in a Mouse Model

(2011) C. J. Harvey et al.   Science Translational Medicine

Randomised vitamin E supplementation and risk of chronic lung disease in the Women's Health Study

(2011) A. H. Agler et al.   THORAX

Cigarette Smoke-Induced Changes to Alveolar Macrophage Phenotype and Function Are Improved by Treatment with Procysteine

(2010) Sandra Hodge et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

COPD in England: a comparison of expected, model-based prevalence and observed prevalence from general practice data

(2010) L. Nacul et al.   JOURNAL OF PUBLIC HEALTH

Superoxide dismutases, lung function and bronchial responsiveness in a general population

(2009) M. Siedlinski et al.   EUROPEAN RESPIRATORY JOURNAL

Chemical and molecular mechanisms of antioxidants: experimental approaches and model systems

(2009) Jian-Ming Lü et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Smoking-Dependent Reprogramming of Alveolar Macrophage Polarization: Implication for Pathogenesis of Chronic Obstructive Pulmonary Disease

(2009) R. Shaykhiev et al.   JOURNAL OF IMMUNOLOGY

Methionine oxidation contributes to bacterial killing by the myeloperoxidase system of neutrophils

(2009) H. Rosen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Persistence of oxidant and protease burden in the airways after smoking cessation

(2009) Noora Louhelainen et al.   BMC Pulmonary Medicine

Superoxide Dismutase 3 Polymorphism Associated with Reduced Lung Function in Two Large Populations

(2008) Morten Dahl et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Down-Regulated NF-E2–Related Factor 2 in Pulmonary Macrophages of Aged Smokers and Patients with Chronic Obstructive Pulmonary Disease

(2008) Masaru Suzuki et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Thioredoxin-1 Ameliorates Cigarette Smoke-Induced Lung Inflammation and Emphysema in Mice

(2008) A. Sato et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

(2008) T. E. Sussan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema

(2008) D Goven et al.   THORAX

Structure and Function of the Polymeric Mucins in Airways Mucus

(2007) David J. Thornton et al.   Annual Review of Physiology

Neutrophil elastase, proteinase 3 and cathepsin G: Physicochemical properties, activity and physiopathological functions

(2007) Brice Korkmaz et al.   BIOCHIMIE

Inter-relationships between inflammatory markers in patients with stable COPD with bronchitis: intra-patient and inter-patient variability

(2007) E Sapey et al.   THORAX