Three-dimensional system enabling the maintenance and directed differentiation of pluripotent stem cells under defined conditions

Defined three-dimensional microenvironments boost induction of pluripotency

(2016) Massimiliano Caiazzo et al.   NATURE MATERIALS

Two-photon polymerized “nichoid” substrates maintain function of pluripotent stem cells when expanded under feeder-free conditions

(2016) Michele M. Nava et al.   Stem Cell Research & Therapy

Small molecule-driven direct conversion of human pluripotent stem cells into functional osteoblasts

(2016) H. Kang et al.   Science Advances

Distributed and Lumped Parameter Models for the Characterization of High Throughput Bioreactors

(2016) Laura Iannetti et al.   PLoS One

Human iPSC-derived osteoblasts and osteoclasts together promote bone regeneration in 3D biomaterials

(2016) Ok Hee Jeon et al.   Scientific Reports

CXXC5 is a negative-feedback regulator of the Wnt/β-catenin pathway involved in osteoblast differentiation

(2015) H-Y Kim et al.   CELL DEATH AND DIFFERENTIATION

Study of bone-like hydroxyapatite/polyamino acid composite materials for their biological properties and effects on the reconstruction of long bone defects

(2015) Ling Yan et al.   Drug Design Development and Therapy

The importance of three-dimensional scaffold structure on stemness maintenance of mouse embryonic stem cells

(2014) Jianshu Wei et al.   BIOMATERIALS

Stepwise Differentiation of Pluripotent Stem Cells into Osteoblasts Using Four Small Molecules under Serum-free and Feeder-free Conditions

(2014) Kosuke Kanke et al.   Stem Cell Reports

Stem cells in a three-dimensional scaffold environment

(2014) Xuan Meng et al.   SpringerPlus

The synergistic effect of a hybrid graphene oxide–chitosan system and biomimetic mineralization on osteoblast functions

(2013) D. Depan et al.   Biomaterials Science

Long-term maintenance of mouse embryonic stem cell pluripotency by manipulating integrin signaling within 3D scaffolds without active Stat3

(2012) Seung Tae Lee et al.   BIOMATERIALS

The Transcriptional and Epigenomic Foundations of Ground State Pluripotency

(2012) Hendrik Marks et al.   CELL

Gli1 Protein Participates in Hedgehog-mediated Specification of Osteoblast Lineage during Endochondral Ossification

(2012) Hironori Hojo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

(2011) Tomoki Nakashima et al.   NATURE MEDICINE

Three-dimensional biomaterials for the study of human pluripotent stem cells

(2011) Thomas P Kraehenbuehl et al.   NATURE METHODS

In vitro osteogenic differentiation of HOS cells on two types of collagen gels

(2010) Takako Takitoh et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Upstream regulatory elements necessary for expression of the rat COL1A1 promoter in transgenic mice

(2010) Zoran Bogdanovic et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Enhanced osteoblastic differentiation of mesenchymal stem cells seeded in RGD-functionalized PLLA scaffolds and cultured in a flow perfusion bioreactor

(2010) Jose F. Alvarez-Barreto et al.   Journal of Tissue Engineering and Regenerative Medicine

Retinoic Acid Synthesis Promotes Development of Neural Progenitors from Mouse Embryonic Stem Cells by Suppressing Endogenous, Wnt-Dependent Nodal Signaling

(2010) Nina Engberg et al.   STEM CELLS

Osteoblasts Derived from Induced Pluripotent Stem Cells form Calcified Structures in Scaffolds Both In Vitro and In Vivo

(2010) Ganna Bilousova et al.   STEM CELLS

Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming

(2009) Wenlin Li et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Patched1 Haploinsufficiency Increases Adult Bone Mass and Modulates Gli3 Repressor Activity

(2008) Shinsuke Ohba et al.   DEVELOPMENTAL CELL

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

Comparison of osteogenesis of human embryonic stem cells within 2D and 3D culture systems

(2008) X.‐F. Tian et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Hypoxia in Static and Dynamic 3D Culture Systems for Tissue Engineering of Bone

(2008) Elias Volkmer et al.   TISSUE ENGINEERING PART A