A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9
Published 2017 View Full Article
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Title
A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9
Authors
Keywords
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Journal
Science Advances
Volume 3, Issue 8, Pages eaao0027
Publisher
American Association for the Advancement of Science (AAAS)
Online
2017-08-05
DOI
10.1126/sciadv.aao0027
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Related references
Note: Only part of the references are listed.- Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
- (2016) Addison V. Wright et al. CELL
- Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9
- (2016) Carolin Anders et al. MOLECULAR CELL
- Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9
- (2016) Seiichi Hirano et al. MOLECULAR CELL
- High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects
- (2016) Benjamin P. Kleinstiver et al. NATURE
- Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA
- (2016) Christopher D Richardson et al. NATURE BIOTECHNOLOGY
- Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage
- (2016) F. Jiang et al. SCIENCE
- Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems
- (2016) Prarthana Mohanraju et al. SCIENCE
- Structural roles of guide RNAs in the nuclease activity of Cas9 endonuclease
- (2016) Youngbin Lim et al. Nature Communications
- Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9
- (2016) Digvijay Singh et al. Nature Communications
- Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations
- (2016) Giulia Palermo et al. ACS Central Science
- Delivery and Specificity of CRISPR/Cas9 Genome Editing Technologies for Human Gene Therapy
- (2015) Jennifer L. Gori et al. HUMAN GENE THERAPY
- Expanding the Biologist’s Toolkit with CRISPR-Cas9
- (2015) Samuel H. Sternberg et al. MOLECULAR CELL
- Conformational control of DNA target cleavage by CRISPR–Cas9
- (2015) Samuel H. Sternberg et al. NATURE
- A Cas9-guide RNA complex preorganized for target DNA recognition
- (2015) F. Jiang et al. SCIENCE
- Rationally engineered Cas9 nucleases with improved specificity
- (2015) I. M. Slaymaker et al. SCIENCE
- Development and Applications of CRISPR-Cas9 for Genome Engineering
- (2014) Patrick D. Hsu et al. CELL
- CRISPR-Cas Systems: Prokaryotes Upgrade to Adaptive Immunity
- (2014) Rodolphe Barrangou et al. MOLECULAR CELL
- Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease
- (2014) Carolin Anders et al. NATURE
- DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
- (2014) Samuel H. Sternberg et al. NATURE
- Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
- (2014) Xuebing Wu et al. NATURE BIOTECHNOLOGY
- Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
- (2014) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- Unravelling the structural and mechanistic basis of CRISPR–Cas systems
- (2014) John van der Oost et al. NATURE REVIEWS MICROBIOLOGY
- G-quadruplex formation in telomeres enhances POT1/TPP1 protection against RPA binding
- (2014) S. Ray et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes
- (2014) Mark D. Szczelkun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The new frontier of genome engineering with CRISPR-Cas9
- (2014) J. A. Doudna et al. SCIENCE
- Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
- (2014) M. Jinek et al. SCIENCE
- Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
- (2012) G. Gasiunas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
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