NKp46 expression on NK cells as a prognostic and predictive biomarker for response to allo-SCT in patients with AML

Expression of NKp46 Splice Variants in Nasal Lavage Following Respiratory Viral Infection: Domain 1-Negative Isoforms Predominate and Manifest Higher Activity

(2017) Yonat Shemer-Avni et al.   Frontiers in Immunology

Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability

(2016) Bernhard Mlecnik et al.   IMMUNITY

Natural killer cells in acute myeloid leukemia patients: from phenotype to transcriptomic analysis

(2016) G. Venton et al.   IMMUNOLOGIC RESEARCH

Survival in acute myeloid leukemia is associated with NKp44 splice variants

(2016) Avishai Shemesh et al.   Oncotarget

Hematopoietic stem cell transplantation for patients with AML in first complete remission

(2015) J. J. Cornelissen et al.   BLOOD

Biomarker: Predictive or Prognostic?

(2015) Karla V. Ballman   JOURNAL OF CLINICAL ONCOLOGY

Defective NK Cells in Acute Myeloid Leukemia Patients at Diagnosis Are Associated with Blast Transcriptional Signatures of Immune Evasion

(2015) Zena Khaznadar et al.   JOURNAL OF IMMUNOLOGY

Acute Myeloid Leukemia

(2015) Hartmut Döhner et al.   NEW ENGLAND JOURNAL OF MEDICINE

Natural cytotoxicity receptor splice variants orchestrate the distinct functions of human natural killer cell subtypes

(2015) Johan Siewiera et al.   Nature Communications

Highly effective NK cells are associated with good prognosis in patients with metastatic prostate cancer

(2015) Christine Pasero et al.   Oncotarget

Role of natural killer cell subsets and natural cytotoxicity receptors for the outcome of immunotherapy in acute myeloid leukemia

(2015) Anna Martner et al.   OncoImmunology

Prognostic significance of myelodysplasia-related changes according to the WHO classification among ELN-intermediate-risk AML patients

(2014) Raynier Devillier et al.   AMERICAN JOURNAL OF HEMATOLOGY

NK Cell Genotype and Phenotype at Diagnosis of Acute Lymphoblastic Leukemia Correlate with Postinduction Residual Disease

(2014) E. M. Sullivan et al.   CLINICAL CANCER RESEARCH

Leukemia-induced phenotypic and functional defects in natural killer cells predict failure to achieve remission in acute myeloid leukemia

(2014) K. Stringaris et al.   HAEMATOLOGICA

Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: a meta-analysis of individual patient data from randomised controlled trials

(2014) Robert K Hills et al.   LANCET ONCOLOGY

NK Cell Receptor NKp46 Regulates Graft-versus-Host Disease

(2014) Hormas Ghadially et al.   Cell Reports

Allogeneic Transplantation Versus Chemotherapy as Postremission Therapy for Acute Myeloid Leukemia: A Prospective Matched Pairs Analysis

(2013) Matthias Stelljes et al.   JOURNAL OF CLINICAL ONCOLOGY

Predicting the Clinical Outcome of Allogeneic Hematopoietic Stem Cell Transplantation: The Long and Winding Road toward Validated Immune Biomarkers

(2013) A. Forcina et al.   Frontiers in Immunology

Natural killer cell immune escape in acute myeloid leukemia

(2012) E Lion et al.   LEUKEMIA

A low thymic function is associated with leukemia relapse in children given T-cell-depleted HLA-haploidentical stem cell transplantation

(2012) E Clave et al.   LEUKEMIA

Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia

(2012) Jay P. Patel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Histopathologic-Based Prognostic Factors of Colorectal Cancers Are Associated With the State of the Local Immune Reaction

(2011) Bernhard Mlecnik et al.   JOURNAL OF CLINICAL ONCOLOGY

Bring on the biomarkers

(2011) George Poste   NATURE

Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors

(2011) Nicolas F Delahaye et al.   NATURE MEDICINE

Innate or Adaptive Immunity? The Example of Natural Killer Cells

(2011) E. Vivier et al.   SCIENCE

Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia

(2010) S. Cooley et al.   BLOOD

Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials

(2010) D. Grimwade et al.   BLOOD

Biomarkers and surrogate end points—the challenge of statistical validation

(2010) Marc Buyse et al.   Nature Reviews Clinical Oncology

Lymphocyte Recovery Is a Major Determinant of Outcome after Matched Unrelated Myeloablative Transplantation for Myelogenous Malignancies

(2009) Katarina Le Blanc et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

(2009) H. Dohner et al.   BLOOD

Low NKp30, NKp46 and NKG2D expression and reduced cytotoxic activity on NK cells in cervical cancer and precursor lesions

(2009) Trinidad Garcia-Iglesias et al.   BMC CANCER

Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia in First Complete Remission

(2009) John Koreth et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effects of activating NK cell receptor expression and NK cell reconstitution on the outcomes of unrelated donor hematopoietic cell transplantation for hematologic malignancies

(2009) B M Triplett et al.   LEUKEMIA