Two immune-enhanced molecular subtypes differ in inflammation, checkpoint signaling and outcome of advanced head and neck squamous cell carcinoma

Pembrolizumab for Platinum- and Cetuximab-Refractory Head and Neck Cancer: Results From a Single-Arm, Phase II Study

(2017) Joshua Bauml et al.   JOURNAL OF CLINICAL ONCOLOGY

STAT3 Induces Immunosuppression by Upregulating PD-1/PD-L1 in HNSCC

(2017) L.L. Bu et al.   JOURNAL OF DENTAL RESEARCH

Immunotherapy for Head and Neck Squamous Cell Carcinoma: A Review of Current and Emerging Therapeutic Options

(2017) Jessica M. Moskovitz et al.   ONCOLOGIST

Memory responses of natural killer cells

(2017) Clair D. Geary et al.   SEMINARS IN IMMUNOLOGY

HPV-Associated Head and Neck Cancer: Unique Features of Epidemiology and Clinical Management

(2016) Jessica H. Maxwell et al.   Annual Review of Medicine

Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8+ T Cells

(2016) E. Beyranvand Nejad et al.   CANCER RESEARCH

Pretreatment count of peripheral neutrophils, monocytes, and lymphocytes as independent prognostic factor in patients with head and neck cancer

(2016) Cristina Valero et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Antitumor Activity of Pembrolizumab in Biomarker-Unselected Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma: Results From the Phase Ib KEYNOTE-012 Expansion Cohort

(2016) Laura Q.M. Chow et al.   JOURNAL OF CLINICAL ONCOLOGY

Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx

(2016) Ankur Chakravarthy et al.   JOURNAL OF CLINICAL ONCOLOGY

Safety and clinical activity of pembrolizumab for treatment of recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-012): an open-label, multicentre, phase 1b trial

(2016) Tanguy Y Seiwert et al.   LANCET ONCOLOGY

Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck

(2016) Robert L. Ferris et al.   NEW ENGLAND JOURNAL OF MEDICINE

Multiplatform-based molecular subtypes of non-small-cell lung cancer

(2016) F Chen et al.   ONCOGENE

Programmed cell death-ligand 1 expression in oral squamous cell carcinoma is associated with an inflammatory phenotype

(2016) Laveniya Satgunaseelan et al.   PATHOLOGY

Gene expression analysis of TIL rich HPV-driven head and neck tumors reveals a distinct B-cell signature when compared to HPV independent tumors

(2016) Oliver Wood et al.   Oncotarget

Oral cavity and oropharyngeal squamous cell carcinoma-an update

(2015) Angela C. Chi et al.   CA-A CANCER JOURNAL FOR CLINICIANS

PD-1 Blockers

(2015) Jedd D. Wolchok   CELL

The role of HPV RNA transcription, immune response-related gene expression and disruptiveTP53mutations in diagnostic and prognostic profiling of head and neck cancer

(2015) Gunnar Wichmann et al.   INTERNATIONAL JOURNAL OF CANCER

Expression of PD-1 and Its Ligands, PD-L1 and PD-L2, in Smokers and Never Smokers with KRAS-Mutant Lung Cancer

(2015) Antonio Calles et al.   Journal of Thoracic Oncology

HPV DNA, E6/E7 mRNA, and p16INK4a detection in head and neck cancers: a systematic review and meta-analysis

(2014) Cathy Ndiaye et al.   LANCET ONCOLOGY

Tumor-infiltrating lymphocytes favor the response to chemoradiotherapy of head and neck cancer

(2014) Panagiotis Balermpas et al.   OncoImmunology

Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

(2013) Gabriela Bindea et al.   IMMUNITY

Molecular Subtypes in Head and Neck Cancer Exhibit Distinct Patterns of Chromosomal Gain and Loss of Canonical Cancer Genes

(2013) Vonn Walter et al.   PLoS One

CD86 Is an Activation Receptor for NK Cell Cytotoxicity against Tumor Cells

(2013) Yanmeng Peng et al.   PLoS One

The Tumor Microenvironment Contribution to Development, Growth, Invasion and Metastasis of Head and Neck Squamous Cell Carcinomas

(2013) Sittichai Koontongkaew   Journal of Cancer

Cancer-associated fibroblasts and macrophages

(2013) Paola Chiarugi   OncoImmunology

PD-1-Expressing Tumor-Infiltrating T Cells Are a Favorable Prognostic Biomarker in HPV-Associated Head and Neck Cancer

(2012) C. Badoual et al.   CANCER RESEARCH

Long-term Follow-up of the RTOG 9501/Intergroup Phase III Trial: Postoperative Concurrent Radiation Therapy and Chemotherapy in High-Risk Squamous Cell Carcinoma of the Head and Neck

(2012) Jay S. Cooper et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer

(2011) Marie Tosolini et al.   CANCER RESEARCH

Inflammation and immune surveillance in cancer

(2011) Melvyn T. Chow et al.   SEMINARS IN CANCER BIOLOGY

ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking

(2010) Matthew D. Wilkerson et al.   BIOINFORMATICS

Overexpression of macrophage inflammatory protein-3α in oral cavity squamous cell carcinoma is associated with nodal metastasis

(2010) Kai-Ping Chang et al.   ORAL ONCOLOGY

Coordination of Intratumoral Immune Reaction and Human Colorectal Cancer Recurrence

(2009) M. Camus et al.   CANCER RESEARCH

Tumour infiltrating lymphocytes in squamous cell carcinoma of the oro- and hypopharynx: Prognostic impact may depend on type of treatment and stage of disease

(2009) Luitpold V. Distel et al.   ORAL ONCOLOGY

Statistical Significance of Clustering for High-Dimension, Low–Sample Size Data

(2008) Yufeng Liu et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION