Anti-Donor Immune Responses Elicited by Allogeneic Mesenchymal Stem Cells and Their Extracellular Vesicles: Are We Still Learning?

Mesenchymal stem cells deliver exogenous miR-21 via exosomes to inhibit nucleus pulposus cell apoptosis and reduce intervertebral disc degeneration

(2017) Xiaofei Cheng et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Regulation of the secretion of immunoregulatory factors of mesenchymal stem cells (MSCs) by collagen-based scaffolds during chondrogenesis

(2017) Jingyu Yang et al.   Materials Science & Engineering C-Materials for Biological Applications

Immunogenicity of hepatic differentiated human umbilical cord mesenchymal stem cells promoted by porcine decellularized liver scaffolds

(2017) Yi Li et al.   XENOTRANSPLANTATION

Immunogenicity of insulin-producing cells derived from human umbilical cord mesenchymal stem cells

(2017) Xiao-Fei Yang et al.   Experimental and Therapeutic Medicine

Repeated intra-articular injection of allogeneic mesenchymal stem cells causes an adverse response compared to autologous cells in the equine model

(2017) Amanda-Jo Joswig et al.   Stem Cell Research & Therapy

Mesenchymal Stem Cells: Time to Change the Name!

(2017) Arnold I. Caplan   Stem Cells Translational Medicine

Safety and Side Effects of Using Placenta-Derived Decidual Stromal Cells for Graft-versus-Host Disease and Hemorrhagic Cystitis

(2017) Arjang Baygan et al.   Frontiers in Immunology

Effects of Mesenchymal Stem Cell-Derived Exosomes on Experimental Autoimmune Uveitis

(2017) Lingling Bai et al.   Scientific Reports

Review article: mesenchymal stromal cell therapy for inflammatory bowel diseases

(2016) C. Grégoire et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Inflammatory response to the administration of mesenchymal stem cells in an equine experimental model: effect of autologous, and single and repeat doses of pooled allogeneic cells in healthy joints

(2016) N. Ardanaz et al.   BMC Veterinary Research

Allogeneic chondrogenically differentiated human mesenchymal stromal cells do not induce immunogenic responses from T lymphocytes in vitro

(2016) Caoimhe H. Kiernan et al.   CYTOTHERAPY

Allogeneic major histocompatibility complex-mismatched equine bone marrow-derived mesenchymal stem cells are targeted for death by cytotoxic anti-major histocompatibility complex antibodies

(2016) A.K. Berglund et al.   EQUINE VETERINARY JOURNAL

Class II transactivator knockdown limits major histocompatibility complex II expression, diminishes immune rejection, and improves survival of allogeneic bone marrow stem cells in the infarcted heart

(2016) Xi-Ping Huang et al.   FASEB JOURNAL

Donor dendritic cell–derived exosomes promote allograft-targeting immune response

(2016) Quan Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunologic properties of differentiated and undifferentiated mesenchymal stem cells derived from umbilical cord blood

(2016) Hyo-Jong Lee et al.   Journal of Veterinary Science

Expanded allogeneic adipose-derived mesenchymal stem cells (Cx601) for complex perianal fistulas in Crohn's disease: a phase 3 randomised, double-blind controlled trial

(2016) Julián Panés et al.   LANCET

Culture expanded primary chondrocytes have potent immunomodulatory properties and do not induce an allogeneic immune response

(2016) P. Lohan et al.   OSTEOARTHRITIS AND CARTILAGE

Cryopreserved Mesenchymal Stromal Cells Are Susceptible to T-Cell Mediated Apoptosis Which Is Partly Rescued by IFNγ Licensing

(2016) Raghavan Chinnadurai et al.   STEM CELLS

Improved osteogenesis and upregulated immunogenicity in human placenta-derived mesenchymal stem cells primed with osteogenic induction medium

(2016) Xuejie Fu et al.   Stem Cell Research & Therapy

Allogeneic Mesenchymal Precursor Cells (MPC) in Diabetic Nephropathy: A Randomized, Placebo-controlled, Dose Escalation Study

(2016) David K. Packham et al.   EBioMedicine

Allogeneic Mesenchymal Precursor Cells in Type 2 Diabetes: A Randomized, Placebo-Controlled, Dose-Escalation Safety and Tolerability Pilot Study

(2015) Jay S. Skyler et al.   DIABETES CARE

Human Placenta-derived Cells (PDA-001) for the Treatment of Moderate-to-severe Crohnʼs Disease

(2015) Gil Y. Melmed et al.   INFLAMMATORY BOWEL DISEASES

Interleukin-17A-Induced Human Mesenchymal Stem Cells Are Superior Modulators of Immunological Function

(2015) Kisha Nandini Sivanathan et al.   STEM CELLS

T Lymphocyte Prestimulation Impairs in a Time-Dependent Manner the Capacity of Adipose Mesenchymal Stem Cells to Inhibit Proliferation: Role of Interferon γ, Poly I:C, and Tryptophan Metabolism in Restoring Adipose Mesenchymal Stem Cell Inhibitory Effect

(2015) Pablo Mancheño-Corvo et al.   STEM CELLS AND DEVELOPMENT

Immunogenicity of Decidual Stromal Cells in an Epidermolysis Bullosa Patient and in Allogeneic Hematopoietic Stem Cell Transplantation Patients

(2015) Helen Kaipe et al.   STEM CELLS AND DEVELOPMENT

Different Procoagulant Activity of Therapeutic Mesenchymal Stromal Cells Derived from Bone Marrow and Placental Decidua

(2015) Guido Moll et al.   STEM CELLS AND DEVELOPMENT

Effects of simvastatin on the osteogenic differentiation and immunomodulation of bone marrow mesenchymal stem cells

(2015) JIANYI NIU et al.   Molecular Medicine Reports

Immunogenicity of allogeneic mesenchymal stem cells transplanted via different routes in diabetic rats

(2014) Le-Hui Gu et al.   Cellular & Molecular Immunology

IDO-Independent Suppression of T Cell Effector Function by IFN- -Licensed Human Mesenchymal Stromal Cells

(2014) R. Chinnadurai et al.   JOURNAL OF IMMUNOLOGY

Mesenchymal stem cells: immune evasive, not immune privileged

(2014) James A Ankrum et al.   NATURE BIOTECHNOLOGY

Allo-Reactivity of Mesenchymal Stem Cells in Rhesus Macaques Is Dose and Haplotype Dependent and Limits Durable Cell Engraftment In Vivo

(2014) Iryna A. Isakova et al.   PLoS One

Exosomes/miRNAs as mediating cell-based therapy of stroke

(2014) Hongqi Xin et al.   Frontiers in Cellular Neuroscience

Changes in immunological profile of allogeneic mesenchymal stem cells after differentiation: should we be concerned?

(2014) Paul Lohan et al.   Stem Cell Research & Therapy

Equine bone marrow-derived mesenchymal stromal cells are heterogeneous in MHC class II expression and capable of inciting an immune response in vitro

(2014) Lauren V Schnabel et al.   Stem Cell Research & Therapy

Immunogenicity of undifferentiated and differentiated allogeneic mouse mesenchymal stem cells

(2014) Blessing Mukonoweshuro et al.   Journal of Tissue Engineering

Myogenic-induced mesenchymal stem cells are capable of modulating the immune response by regulatory T cells

(2014) Sunyoung Joo et al.   Journal of Tissue Engineering

Preserving Prostaglandin E2 Level Prevents Rejection of Implanted Allogeneic Mesenchymal Stem Cells and Restores Postinfarction Ventricular Function

(2013) S. Dhingra et al.   CIRCULATION

Chondrogenic Differentiation Increases Antidonor Immune Response to Allogeneic Mesenchymal Stem Cell Transplantation

(2013) Aideen E Ryan et al.   MOLECULAR THERAPY

Anti-donor immune responses elicited by allogeneic mesenchymal stem cells: what have we learned so far?

(2012) Matthew D Griffin et al.   IMMUNOLOGY AND CELL BIOLOGY

Tissue factor–bearing exosome secretion from human mechanically stimulated bronchial epithelial cells in vitro and in vivo

(2012) Jin-Ah Park et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Immunogenicity of allogeneic mesenchymal stem cells

(2011) Sabine Schu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Immunogenicity of Bovine and Leporine Articular Chondrocytes and Meniscus Cells

(2011) Daniel J. Huey et al.   TISSUE ENGINEERING PART A

The role of multipotent marrow stromal cells (MSCs) in tissue regeneration

(2011) Florian Tögel et al.   Organogenesis

Differentiation of Allogeneic Mesenchymal Stem Cells Induces Immunogenicity and Limits Their Long-Term Benefits for Myocardial Repair

(2010) Xi-Ping Huang et al.   CIRCULATION

Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study

(2008) Katarina Le Blanc et al.   LANCET