The Role of Transforming Growth Factor Beta-1 in the Progression of HIV/AIDS and Development of Non-AIDS-Defining Fibrotic Disorders

Human Immunodeficiency Virus Infection, Antiretroviral Therapy, and Liver Pathology

(2017) Mark W. Sonderup et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Increased Risk of Myocardial Infarction in HIV-Infected Individuals in North America Compared With the General Population

(2017) Daniel R. Drozd et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

HIV/HCV coinfection and the risk of cardiovascular disease: A meta-analysis

(2017) O. Osibogun et al.   JOURNAL OF VIRAL HEPATITIS

Changes of transforming growth factor beta 1 in patients with type 2 diabetes and diabetic nephropathy

(2017) Yong-Chao Qiao et al.   MEDICINE

TGF-β3 Inhibits Antibody Production by Human B Cells

(2017) Yumi Tsuchida et al.   PLoS One

Higher plasma transforming growth factor (TGF)-β is associated with kidney disease in older community dwelling adults

(2017) Tapan Mehta et al.   BMC Nephrology

Types of Myocardial Infarction Among Human Immunodeficiency Virus–Infected Individuals in the United States

(2017) Heidi M. Crane et al.   JAMA Cardiology

Transforming growth factor-β1-mediated cardiac fibrosis

(2016) Jasimuddin Ahamed et al.   AIDS

Novel relationships of markers of monocyte activation and endothelial dysfunction with pulmonary dysfunction in HIV-infected persons

(2016) Meghan E. Fitzpatrick et al.   AIDS

Unchanged Levels of Soluble CD14 and IL-6 Over Time Predict Serious Non-AIDS Events in HIV-1-Infected People

(2016) Meena Sunil et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Transforming Growth Factor-β: Master Regulator of the Respiratory System in Health and Disease

(2016) Yael Aschner et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Abacavir and cardiovascular disease: A critical look at the data

(2016) Josep M. Llibre et al.   ANTIVIRAL RESEARCH

Dissecting How CD4 T Cells Are Lost During HIV Infection

(2016) Gilad Doitsh et al.   Cell Host & Microbe

Cardiac Fibrosis

(2016) Joshua G. Travers et al.   CIRCULATION RESEARCH

HIV-1–Related Cardiovascular Disease Is Associated With Chronic Inflammation, Frequent Pericardial Effusions, and Probable Myocardial EdemaCLINICAL PERSPECTIVE

(2016) Ntobeko Ntusi et al.   Circulation-Cardiovascular Imaging

Inflammation and Fibrosis in HIV

(2016) Priscilla Y. Hsue et al.   Circulation-Cardiovascular Imaging

Cardiac Magnetic Resonance Reveals Signs of Subclinical Myocardial Inflammation in Asymptomatic HIV-Infected PatientsCLINICAL PERSPECTIVE

(2016) Julian A. Luetkens et al.   Circulation-Cardiovascular Imaging

HIV Infection, Immunosuppression, and Age at Diagnosis of Non-AIDS-Defining Cancers

(2016) Meredith S. Shiels et al.   CLINICAL INFECTIOUS DISEASES

HIV Infection and Myocardial Infarction

(2016) Leonardo Calza   CURRENT HIV RESEARCH

Cytokines and persistent viral infections

(2016) Jean-Christophe Beltra et al.   CYTOKINE

Prevalence and distribution of non-AIDS causes of death among HIV-infected individuals receiving antiretroviral therapy: a systematic review and meta-analysis

(2016) Mansour Farahani et al.   INTERNATIONAL JOURNAL OF STD & AIDS

Risk Factors Associated With Quantitative Evidence of Lung Emphysema and Fibrosis in an HIV-Infected Cohort

(2016) Joseph K. Leader et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Do Biomarkers of Inflammation, Monocyte Activation, and Altered Coagulation Explain Excess Mortality Between HIV Infected and Uninfected People?

(2016) Kaku A. So-Armah et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Interleukin 6 Is a Stronger Predictor of Clinical Events Than High-Sensitivity C-Reactive Protein or D-Dimer During HIV Infection

(2016) Álvaro H. Borges et al.   JOURNAL OF INFECTIOUS DISEASES

Plasma Soluble CD163 Level Independently Predicts All-Cause Mortality in HIV-1–Infected Individuals

(2016) Troels Bygum Knudsen et al.   JOURNAL OF INFECTIOUS DISEASES

Monocyte Activation Is Associated With Worse Cognitive Performance in HIV-Infected Women With Virologic Suppression

(2016) Brandon M. Imp et al.   JOURNAL OF INFECTIOUS DISEASES

Systemic Immune Activation Profiles of HIV-1 Subtype C-Infected Children and Their Mothers

(2016) Tinyiko G. Makhubele et al.   MEDIATORS OF INFLAMMATION

TGF-β: the master regulator of fibrosis

(2016) Xiao-ming Meng et al.   Nature Reviews Nephrology

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

(2016) Sébastien Viel et al.   Science Signaling

Hepatitis B co-infection in HIV-infected patients receiving antiretroviral therapy at the TC Newman Anti Retroviral Treatment Clinic in Paarl, Western Cape

(2016) Jeanmari King et al.   SOUTHERN AFRICAN JOURNAL OF HIV MEDICINE

TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology

(2016) Masato Morikawa et al.   Cold Spring Harbor Perspectives in Biology

TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

(2016) Sébastien Viel et al.   Science Signaling

Non-infectious Pulmonary Diseases and HIV

(2016) M. Triplette et al.   Current HIV/AIDS Reports

Cause-Specific Mortality in HIV-Positive Patients Who Survived Ten Years after Starting Antiretroviral Therapy

(2016) Adam Trickey et al.   PLoS One

The burden of dialysis-requiring acute kidney injury among hospitalized adults with HIV infection

(2015) Girish N. Nadkarni et al.   AIDS

The TGF-β superfamily in dendritic cell biology

(2015) Pascal Seeger et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Liver fibrosis, microbial translocation and immune activation markers in HIV and HCV infections and in HIV/HCV co-infection

(2015) Paolo Sacchi et al.   DIGESTIVE AND LIVER DISEASE

Impact of HIV infection and smoking on lung immunity and related disorders

(2015) Theresa M. Rossouw et al.   EUROPEAN RESPIRATORY JOURNAL

Fibroblastic Reticular Cells: Organization and Regulation of the T Lymphocyte Life Cycle

(2015) Flavian D. Brown et al.   JOURNAL OF IMMUNOLOGY

Abnormal Myocardial Function Is Related to Myocardial Steatosis and Diffuse Myocardial Fibrosis in HIV-Infected Adults

(2015) Diana K. Thiara et al.   JOURNAL OF INFECTIOUS DISEASES

Liposomal Glutathione Supplementation Restores TH1 Cytokine Response toMycobacterium tuberculosisInfection in HIV-Infected Individuals

(2015) Judy Ly et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Platelet leukocyte aggregates and markers of platelet aggregation, immune activation and disease progression in HIV infected treatment naive asymptomatic individuals

(2015) Bongani B. Nkambule et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

HIV-associated nephropathies: epidemiology, pathology, mechanisms and treatment

(2015) Avi Z. Rosenberg et al.   Nature Reviews Nephrology

Immune Activation Response in Chronic HIV-Infected Patients: Influence of Hepatitis C Virus Coinfection

(2015) Mercedes Márquez et al.   PLoS One

Chronic obstructive pulmonary disease in patients with HIV: an emerging problem

(2014) Andrew T Scourfield et al.   BRITISH JOURNAL OF HOSPITAL MEDICINE

Comparison of Risk and Age at Diagnosis of Myocardial Infarction, End-Stage Renal Disease, and Non-AIDS-Defining Cancer in HIV-Infected Versus Uninfected Adults

(2014) Keri N. Althoff et al.   CLINICAL INFECTIOUS DISEASES

Molecular Mechanisms of Liver Fibrosis in HIV/HCV Coinfection

(2014) Claudio Mastroianni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Increased Arterial Inflammation Relates to High-risk Coronary Plaque Morphology in HIV-Infected Patients

(2014) Ahmed Tawakol et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

TGF-  Utilizes SMAD3 to Inhibit CD16-Mediated IFN-  Production and Antibody-Dependent Cellular Cytotoxicity in Human NK Cells

(2014) R. Trotta et al.   JOURNAL OF IMMUNOLOGY

Antifibrotic Therapy in Simian Immunodeficiency Virus Infection Preserves CD4+ T-Cell Populations and Improves Immune Reconstitution With Antiretroviral Therapy

(2014) Jacob D. Estes et al.   JOURNAL OF INFECTIOUS DISEASES

Soluble Markers of Inflammation and Coagulation but Not T-Cell Activation Predict Non–AIDS-Defining Morbid Events During Suppressive Antiretroviral Treatment

(2014) Allan R. Tenorio et al.   JOURNAL OF INFECTIOUS DISEASES

The changing epidemiology of HIV-related chronic kidney disease in the era of antiretroviral therapy

(2014) Sandeep K. Mallipattu et al.   KIDNEY INTERNATIONAL

Circulating Biomarkers of Immune Activation Distinguish Viral Suppression from Nonsuppression in HAART-Treated Patients with Advanced HIV-1 Subtype C Infection

(2014) Glen Malherbe et al.   MEDIATORS OF INFLAMMATION

HIV-1 Infected Peripheral Blood Mononuclear Cells Modulate the Fibrogenic Activity of Hepatic Stellate Cells through Secreted TGF-β and JNK Signaling

(2014) Deepti Gupta et al.   PLoS One

Chronic Toll-like receptor 4 stimulation in skin induces inflammation, macrophage activation, transforming growth factor beta signature gene expression, and fibrosis

(2014) Giuseppina Stifano et al.   ARTHRITIS RESEARCH & THERAPY

Liver fibrosis in HIV

(2014) Jürgen K. Rockstroh et al.   Current Opinion in HIV and AIDS

Non-AIDS-Defining Malignancies in the HIV-Infected Population

(2014) Chia-ching J. Wang et al.   Current Infectious Disease Reports

TGF-β Activation and Function in Immunity

(2013) Mark A. Travis et al.   Annual Review of Immunology

HIV protease inhibitors and onset of cardiovascular diseases: A central role for oxidative stress and dysregulation of the ubiquitin–proteasome system

(2013) Kathleen M.S.E. Reyskens et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Antiretroviral Therapy Reduces the Rate of Hepatic Decompensation Among HIV- and Hepatitis C Virus–Coinfected Veterans

(2013) Jeffrey P. Anderson et al.   CLINICAL INFECTIOUS DISEASES

Association between AKI and Long-Term Renal and Cardiovascular Outcomes in United States Veterans

(2013) L. S. Chawla et al.   Clinical Journal of the American Society of Nephrology

Microbial Translocation in the Pathogenesis of HIV Infection and AIDS

(2013) Giulia Marchetti et al.   CLINICAL MICROBIOLOGY REVIEWS

Human immunodeficiency virus and liver disease forum 2012

(2013) Kenneth E. Sherman et al.   HEPATOLOGY

HIV-associated chronic immune activation

(2013) Mirko Paiardini et al.   IMMUNOLOGICAL REVIEWS

Immunoregulatory T Cells May Be Involved in Preserving CD4 T Cell Counts in HIV-Infected Long-Term Nonprogressors and Controllers

(2013) Julie C. Gaardbo et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Microbial Translocation and Liver Disease Progression in Women Coinfected With HIV and Hepatitis C Virus

(2013) A. L. French et al.   JOURNAL OF INFECTIOUS DISEASES

HIV and Coronary Heart Disease

(2013) Franck Boccara et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Transforming Growth Factor-β1 and Tumor Necrosis Factor-α are Associated with Clinical Severity and Airflow Limitation of COPD in an Additive Manner

(2013) Chi-Huei Chiang et al.   LUNG

Risk of Cardiovascular Disease from Antiretroviral Therapy for HIV: A Systematic Review

(2013) Clay Bavinger et al.   PLoS One

HIV Infection and the Risk of Acute Myocardial Infarction

(2013) Matthew S. Freiberg et al.   JAMA Internal Medicine

Transforming growth factor-beta1 in inflammatory airway disease: a key for understanding inflammation and remodeling

(2012) Y. C. Yang et al.   ALLERGY

HIV infection, lymphoid fibrosis, and disease

(2012) S. G. Deeks   BLOOD

The split personality of regulatory T cells in HIV infection

(2012) M. F. Chevalier et al.   BLOOD

Relative risk of renal disease among people living with HIV: a systematic review and meta-analysis

(2012) Fakhrul M Islam et al.   BMC PUBLIC HEALTH

Inhibition of dendritic cell migration by transforming growth factor-β1 increases tumor-draining lymph node metastasis

(2012) Kazuhiro Imai et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Sudden Cardiac Death in Patients With Human Immunodeficiency Virus Infection

(2012) Zian H. Tseng et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

Microbial translocation, immune activation, and HIV disease

(2012) Nichole R. Klatt et al.   TRENDS IN MICROBIOLOGY

Lymphoid Tissue Damage in HIV-1 Infection Depletes Naïve T Cells and Limits T Cell Reconstitution after Antiretroviral Therapy

(2012) Ming Zeng et al.   PLoS Pathogens

Pathogenesis of Liver Fibrosis

(2011) Virginia Hernandez-Gea et al.   Annual Review of Pathology-Mechanisms of Disease

Role of TGF-β in chronic kidney disease: an integration of tubular, glomerular and vascular effects

(2011) Francisco J. López-Hernández et al.   CELL AND TISSUE RESEARCH

Unveiling the Mechanisms for Decreased Glutathione in Individuals with HIV Infection

(2011) Devin Morris et al.   Clinical & Developmental Immunology

HIV-associated nephropathy: pathogenesis

(2011) Raj K Medapalli et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Evolution of hepatic fibrosis research

(2011) Norifumi Kawada   HEPATOLOGY RESEARCH

Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections

(2011) Ming Zeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Soluble markers of inflammation are associated with Framingham scores in HIV-infected patients on suppressive antiretroviral therapy

(2011) María Guzmán-Fulgencio et al.   JOURNAL OF INFECTION

Plasma Levels of Soluble CD14 Independently Predict Mortality in HIV Infection

(2011) Netanya G. Sandler et al.   JOURNAL OF INFECTIOUS DISEASES

Renal Disease Associated with Antiretroviral Therapy in the Treatment of HIV

(2011) Ryan D. Cooper et al.   NEPHRON CLINICAL PRACTICE

Human Tumour Immune Evasion via TGF-β Blocks NK Cell Activation but Not Survival Allowing Therapeutic Restoration of Anti-Tumour Activity

(2011) Erica B. Wilson et al.   PLoS One

Making sense of regulatory T cell suppressive function

(2011) Itay Shalev et al.   SEMINARS IN IMMUNOLOGY

TGF-β: the sword, the wand, and the shield of FOXP3+ regulatory T cells

(2011) Dat Q. Tran   Journal of Molecular Cell Biology

HIV Infection and Risk for Incident Pulmonary Diseases in the Combination Antiretroviral Therapy Era

(2010) Kristina Crothers et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Cellular immune responses to HCV core increase and HCV RNA levels decrease during successful antiretroviral therapy

(2010) J. Rohrbach et al.   GUT

Clinical syndromes and consequences of antiretroviral-related hepatotoxicity

(2010) Marina Núñez   HEPATOLOGY

Transforming Growth Factor-β Signaling Curbs Thymic Negative Selection Promoting Regulatory T Cell Development

(2010) Weiming Ouyang et al.   IMMUNITY

Cellular and molecular basis for the regulation of inflammation by TGF- 

(2010) A. Yoshimura et al.   JOURNAL OF BIOCHEMISTRY

Prevalence of chronic hepatitis B virus infection among patients in the HIV Outpatient Study, 1996-2007†

(2010) P. R. Spradling et al.   JOURNAL OF VIRAL HEPATITIS

Does Inflammation Fuel the Fire in CKD?

(2009) Dena E. Rifkin et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Oxidative stress and glutathione in TGF-β-mediated fibrogenesis

(2009) R.-M. Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

TGF-beta signal transduction in chronic kidney disease

(2009) H. et al.   Frontiers in Bioscience-Landmark

HIV-1 binding to CD4 on CD4+CD25+ regulatory T cells enhances their suppressive function and induces them to home to, and accumulate in, peripheral and mucosal lymphoid tissues: an additional mechanism of immunosuppression

(2009) J. Ji et al.   INTERNATIONAL IMMUNOLOGY

Non-Smad pathways in TGF-β signaling

(2008) Ying E Zhang   CELL RESEARCH

Effects of HIV Infection and Antiretroviral Therapy on the Heart and Vasculature

(2008) Michael P. Dubé et al.   CIRCULATION

HIV Increases HCV Replication in a TGF-β1–Dependent Manner

(2008) Wenyu Lin et al.   GASTROENTEROLOGY

Transforming Growth Factor- 1, Transforming Growth Factor- 2, and Transforming Growth Factor- 3 Enhance Ovarian Cancer Metastatic Potential by Inducing a Smad3-Dependent Epithelial-to-Mesenchymal Transition

(2008) T.-V. Do et al.   MOLECULAR CANCER RESEARCH

Acute Kidney Injury in HIV-Infected Patients

(2008) Sahir Kalim et al.   SEMINARS IN NEPHROLOGY

HIV-Associated Nephropathy: Clinical Presentation, Pathology, and Epidemiology in the Era of Antiretroviral Therapy

(2008) Christina M. Wyatt et al.   SEMINARS IN NEPHROLOGY

Hepatic fibrosis—Overview

(2008) Scott L. Friedman   TOXICOLOGY