The Induction and Maintenance of Transplant Tolerance Engages Both Regulatory and Anergic CD4+ T cells

CD4+ T cell anergy prevents autoimmunity and generates regulatory T cell precursors

(2016) Lokesh A Kalekar et al.   NATURE IMMUNOLOGY

TGFβ-dependent expression of PD-1 and PD-L1 controls CD8+ T cell anergy in transplant tolerance

(2016) Marije Baas et al.   eLife

Control of Immune Response to Allogeneic Embryonic Stem Cells by CD3 Antibody-Mediated Operational Tolerance Induction

(2015) D. Calderon et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Heterogeneous CD3 Expression Levels in Differing T Cell Subsets Correlate with the In Vivo Anti-CD3–Mediated T Cell Modulation

(2015) Andrea Valle et al.   JOURNAL OF IMMUNOLOGY

Immune homeostasis enforced by co-localized effector and regulatory T cells

(2015) Zhiduo Liu et al.   NATURE

Regulatory T Cells: Serious Contenders in the Promise for Immunological Tolerance in Transplantation

(2015) Niloufar Safinia et al.   Frontiers in Immunology

In VivoEnvironment Necessary to Support Transplanted Donor Mouse T Regulatory Cells

(2014) C. Cabello-Kindelan et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Equivalent Specificity of Peripheral Blood and Islet-Infiltrating CD8+ T Lymphocytes in Spontaneously Diabetic HLA-A2 Transgenic NOD Mice

(2014) E. Enee et al.   JOURNAL OF IMMUNOLOGY

Delayed Anti-CD3 Therapy Results in Depletion of Alloreactive T Cells and the Dominance of Foxp3+CD4+Graft Infiltrating Cells

(2013) R. Goto et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Adjuvant facilitates tolerance induction to factor VIII in hemophilic mice through a Foxp3-independent mechanism that relies on IL-10

(2013) V. G. Oliveira et al.   BLOOD

Cutting Edge: Type 1 Diabetes Occurs despite Robust Anergy among Endogenous Insulin-Specific CD4 T Cells in NOD Mice

(2013) K. E. Pauken et al.   JOURNAL OF IMMUNOLOGY

Characteristics of TCR/CD3 complex CD3ɛ chains of regulatory CD4+ T (Treg) lymphocytes: role in Treg differentiation in vitro and impact on Treg in vivo

(2013) Jose M. Rojo et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Regulatory Cells and Transplantation Tolerance

(2013) S. P. Cobbold et al.   Cold Spring Harbor Perspectives in Medicine

Induction of Allograft Tolerance by Monoclonal CD3 Antibodies: A Matter of Timing

(2012) S. You et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Sustained suppression by Foxp3+regulatory T cells is vital for infectious transplantation tolerance

(2011) Adrian R. Kendal et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Arthritogenic Self-Reactive CD4+ T Cells Acquire an FR4hiCD73hi Anergic State in the Presence of Foxp3+ Regulatory T Cells

(2011) R. J. Martinez et al.   JOURNAL OF IMMUNOLOGY

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

(2010) C. G. Brunstein et al.   BLOOD

Costimulatory pathways in transplantation: challenges and new developments

(2009) Xian C. Li et al.   IMMUNOLOGICAL REVIEWS