Delayed Anti-CD3 Therapy Results in Depletion of Alloreactive T Cells and the Dominance of Foxp3+CD4+Graft Infiltrating Cells

T Cell-Dendritic Cell Immunological Synapses Contain TCR-dependent CD28-CD80 Clusters That Recruit Protein Kinase C 

(2014) S.-Y. Tseng et al.   JOURNAL OF IMMUNOLOGY

Induction of Allograft Tolerance by Monoclonal CD3 Antibodies: A Matter of Timing

(2012) S. You et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Sustained suppression by Foxp3+regulatory T cells is vital for infectious transplantation tolerance

(2011) Adrian R. Kendal et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Anti-CD3 Therapy Promotes Tolerance by Selectively Depleting Pathogenic Cells while Preserving Regulatory T Cells

(2011) C. Penaranda et al.   JOURNAL OF IMMUNOLOGY

Type 1 diabetes mellitus—a door opening to a real therapy?

(2011) Lucienne Chatenoud   Nature Reviews Endocrinology

Mechanisms of Rejection: Current Perspectives

(2011) Kathryn J. Wood et al.   TRANSPLANTATION

CD4+ Regulatory T Cells Generated in Vitro with IFN-γ and Allogeneic APC Inhibit Transplant Arteriosclerosis

(2010) Gregor Warnecke et al.   AMERICAN JOURNAL OF PATHOLOGY

New generation CD3 monoclonal antibodies: are we ready to have them back in clinical transplantation?

(2010) Sylvaine You et al.   Current Opinion in Organ Transplantation

Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass

(2010) B. Keymeulen et al.   DIABETOLOGIA

In vivo prevention of transplant arteriosclerosis by ex vivo–expanded human regulatory T cells

(2010) Satish N Nadig et al.   NATURE MEDICINE

Ex Vivo–Expanded Human Regulatory T Cells Prevent the Rejection of Skin Allografts in a Humanized Mouse Model

(2010) Fadi Issa et al.   TRANSPLANTATION

Rapamycin Prevents and Breaks the Anti-CD3-Induced Tolerance in NOD Mice

(2009) A. Valle et al.   DIABETES

Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor

(2009) Makoto Miyara et al.   IMMUNITY