Differences in Granule Morphology yet Equally Impaired Exocytosis among Cytotoxic T Cells and NK Cells from Chediak–Higashi Syndrome Patients

Phosphoinositides in Control of Membrane Dynamics

(2016) Kay O. Schink et al.   Annual Review of Cell and Developmental Biology

Chediak-Higashi syndrome: Lysosomal trafficking regulator domains regulate exocytosis of lytic granules but not cytokine secretion by natural killer cells

(2016) Aleksandra Gil-Krzewska et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

ACaenorhabditis elegansHomologue of LYST Functions in Endosome and Lysosome-Related Organelle Biogenesis

(2016) Alec Barrett et al.   TRAFFIC

Spectrum of Atypical Clinical Presentations in Patients with BiallelicPRF1Missense Mutations

(2015) Bianca Tesi et al.   PEDIATRIC BLOOD & CANCER

LYST Controls the Biogenesis of the Endosomal Compartment Required for Secretory Lysosome Function

(2015) Fernando E. Sepulveda et al.   TRAFFIC

Targeted high-throughput sequencing for genetic diagnostics of hemophagocytic lymphohistiocytosis

(2015) Bianca Tesi et al.   Genome Medicine

Cancer risk in relatives of patients with a primary disorder of lymphocyte cytotoxicity: a retrospective cohort study

(2015) Alexandra Löfstedt et al.   Lancet Haematology

Pathophysiology and spectrum of diseases caused by defects in lymphocyte cytotoxicity

(2014) Marie Meeths et al.   EXPERIMENTAL CELL RESEARCH

Cell biological steps and checkpoints in accessing NK cell cytotoxicity

(2014) Emily M Mace et al.   IMMUNOLOGY AND CELL BIOLOGY

Dictyostelium LvsB has a regulatory role in endosomal vesicle fusion

(2014) Kristin Falkenstein et al.   JOURNAL OF CELL SCIENCE

LYST Affects Lysosome Size and Quantity, but not Trafficking or Degradation Through Autophagy or Endocytosis

(2014) Petter Holland et al.   TRAFFIC

Comparison of primary human cytotoxic T-cell and natural killer cell responses reveal similar molecular requirements for lytic granule exocytosis but differences in cytokine production

(2013) S. C. C. Chiang et al.   BLOOD

Atypical Chédiak-Higashi syndrome with attenuated phenotype: three adult siblings homozygous for a novel LYST deletion and with neurodegenerative disease

(2013) James D Weisfeld-Adams et al.   Orphanet Journal of Rare Diseases

Elevated Granzyme B in Cytotoxic Lymphocytes is a Signature of Immune Activation in Hemophagocytic Lymphohistiocytosis

(2013) Sabine Mellor-Heineke et al.   Frontiers in Immunology

A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes

(2012) Y. T. Bryceson et al.   BLOOD

Controversies in granzyme biology

(2012) O. Susanto et al.   TISSUE ANTIGENS

Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome

(2011) B. Jessen et al.   BLOOD

A novel single point mutation of the LYST gene in two siblings with different phenotypic features of Chediak Higashi syndrome

(2011) Zuhre Kaya et al.   PEDIATRIC BLOOD & CANCER

Natural Killer Cell Lytic Granule Secretion Occurs through a Pervasive Actin Network at the Immune Synapse

(2011) Gregory D. Rak et al.   PLOS BIOLOGY

Remodelling of Cortical Actin Where Lytic Granules Dock at Natural Killer Cell Immune Synapses Revealed by Super-Resolution Microscopy

(2011) Alice C. N. Brown et al.   PLOS BIOLOGY

Spectrum of clinical presentations in familial hemophagocytic lymphohistiocytosis type 5 patients with mutations in STXBP2

(2010) M. Meeths et al.   BLOOD

Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity

(2009) S. M. Wood et al.   BLOOD

Temperature sensitivity of human perforin mutants unmasks subtotal loss of cytotoxicity, delayed FHL, and a predisposition to cancer

(2009) J. Chia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WIP is essential for lytic granule polarization and NK cell cytotoxicity

(2008) K. Krzewski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA