Cross-Protective Efficacy of Influenza Virus M2e Containing Virus-Like Particles Is Superior to Hemagglutinin Vaccines and Variable Depending on the Genetic Backgrounds of Mice

From Original Antigenic Sin to the Universal Influenza Virus Vaccine

(2018) Carole Henry et al.   TRENDS IN IMMUNOLOGY

A Novel Vaccination Strategy Mediating the Induction of Lung-Resident Memory CD8 T Cells Confers Heterosubtypic Immunity against Future Pandemic Influenza Virus

(2016) Yu-Na Lee et al.   JOURNAL OF IMMUNOLOGY

Roles of Aluminum Hydroxide and Monophosphoryl Lipid A Adjuvants in Overcoming CD4+T Cell Deficiency To Induce Isotype-Switched IgG Antibody Responses and Protection by T-Dependent Influenza Vaccine

(2016) Eun-Ju Ko et al.   JOURNAL OF IMMUNOLOGY

Long-Lasting Cross-Protection Against Influenza A by Neuraminidase and M2e-based immunization strategies

(2016) Michael Schotsaert et al.   Scientific Reports

Fc receptor is not required for inducing antibodies but plays a critical role in conferring protection after influenza M2 vaccination

(2014) Yu-Na Lee et al.   IMMUNOLOGY

Roles of Major Histocompatibility Complex Class II in Inducing Protective Immune Responses to Influenza Vaccination

(2014) Eunju O et al.   JOURNAL OF VIROLOGY

Influenza M2 virus-like particles confer a broader range of cross protection to the strain-specific pre-existing immunity

(2014) Min-Chul Kim et al.   VACCINE

AS04-adjuvanted virus-like particles containing multiple M2 extracellular domains of influenza virus confer improved protection

(2014) Yu-Na Lee et al.   VACCINE

In the Shadow of Hemagglutinin: A Growing Interest in Influenza Viral Neuraminidase and Its Role as a Vaccine Antigen

(2014) Teddy Wohlbold et al.   Viruses-Basel

Multiple heterologous M2 extracellular domains presented on virus-like particles confer broader and stronger M2 immunity than live influenza A virus infection

(2013) Min-Chul Kim et al.   ANTIVIRAL RESEARCH

Mucosal Adjuvants for Influenza Virus-Like Particle Vaccine

(2013) Fu-Shi Quan et al.   VIRAL IMMUNOLOGY

New World Bats Harbor Diverse Influenza A Viruses

(2013) Suxiang Tong et al.   PLoS Pathogens

Virus-like Particles Containing Multiple M2 Extracellular Domains Confer Improved Cross-protection Against Various Subtypes of Influenza Virus

(2012) Min-Chul Kim et al.   MOLECULAR THERAPY

Natural and long-lasting cellular immune responses against influenza in the M2e-immune host

(2012) M Schotsaert et al.   Mucosal Immunology

Increased Immunogenicity and Protective Efficacy of Influenza M2e Fused to a Tetramerizing Protein

(2012) Anne-Marie Carola Andersson et al.   PLoS One

Virus-Like Particle Vaccine Containing Hemagglutinin Confers Protection against 2009 H1N1 Pandemic Influenza

(2011) M. Jaber Hossain et al.   Clinical and Vaccine Immunology

Proteomic Characterization of Influenza H5N1 Virus-like Particles and Their Protective Immunogenicity

(2011) Jae-Min Song et al.   JOURNAL OF PROTEOME RESEARCH

Influenza Virus-Like Particles Containing M2 Induce Broadly Cross Protective Immunity

(2011) Jae-Min Song et al.   PLoS One

Universal Vaccine Based on Ectodomain of Matrix Protein 2 of Influenza A: Fc Receptors and Alveolar Macrophages Mediate Protection

(2010) K. El Bakkouri et al.   JOURNAL OF IMMUNOLOGY

Vaccination inducing broad and improved cross protection against multiple subtypes of influenza A virus

(2010) J.-M. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic control of immune responses to influenza A matrix 2 protein (M2)

(2010) Julia A. Misplon et al.   VACCINE

Protective immunity against H5N1 influenza virus by a single dose vaccination with virus-like particles

(2010) Jae-Min Song et al.   VIROLOGY

Host Genetic Background Strongly Influences the Response to Influenza A Virus Infections

(2009) Barkha Srivastava et al.   PLoS One

Comparative immunogenicity evaluations of influenza A virus M2 peptide as recombinant virus like particle or conjugate vaccines in mice and monkeys

(2009) Tong-Ming Fu et al.   VACCINE

The co-administration of CpG-ODN influenced protective activity of influenza M2e vaccine

(2009) Fan Wu et al.   VACCINE

CTA1-M2e-DD: A novel mucosal adjuvant targeted influenza vaccine

(2008) Dubravka Grdic Eliasson et al.   VACCINE

Efficient induction of mucosal and systemic immune responses by virus-like particles administered intranasally: implications for vaccine design

(2007) Juliana Bessa et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Potent immunogenicity and efficacy of a universal influenza vaccine candidate comprising a recombinant fusion protein linking influenza M2e to the TLR5 ligand flagellin

(2007) James W. Huleatt et al.   VACCINE