In the Shadow of Hemagglutinin: A Growing Interest in Influenza Viral Neuraminidase and Its Role as a Vaccine Antigen

Assessment of Influenza Virus Hemagglutinin Stalk-Based Immunity in Ferrets

(2014) F. Krammer et al.   JOURNAL OF VIROLOGY

Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study

(2014) HaiYing Chen et al.   LANCET

Stability of neuraminidase in inactivated influenza vaccines

(2014) Ishrat Sultana et al.   VACCINE

Toward a Universal Influenza Virus Vaccine: Prospects and Challenges

(2013) Natalie Pica et al.   Annual Review of Medicine

Universal anti-neuraminidase antibody inhibiting all influenza A subtypes

(2013) Tracey M. Doyle et al.   ANTIVIRAL RESEARCH

A monoclonal antibody targeting a highly conserved epitope in influenza B neuraminidase provides protection against drug resistant strains

(2013) Tracey M. Doyle et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Humoral and cellular responses to a non-adjuvanted monovalent H1N1 pandemic influenza vaccine in hospital employees

(2013) Ma Teresa Herrera et al.   BMC INFECTIOUS DISEASES

Origin and Molecular Characteristics of a Novel 2013 Avian Influenza A(H6N1) Virus Causing Human Infection in Taiwan

(2013) Jian Yuan et al.   CLINICAL INFECTIOUS DISEASES

Safety and Immunogenicity of a Vero Cell Culture-Derived Whole-Virus Influenza A(H5N1) Vaccine in a Pediatric Population

(2013) M. V. W. van der Velden et al.   JOURNAL OF INFECTIOUS DISEASES

Molecular Basis for Broad Neuraminidase Immunity: Conserved Epitopes in Seasonal and Pandemic H1N1 as Well as H5N1 Influenza Viruses

(2013) H. Wan et al.   JOURNAL OF VIROLOGY

H3 Stalk-Based Chimeric Hemagglutinin Influenza Virus Constructs Protect Mice from H7N9 Challenge

(2013) F. Krammer et al.   JOURNAL OF VIROLOGY

H3N2 Influenza Virus Infection Induces Broadly Reactive Hemagglutinin Stalk Antibodies in Humans and Mice

(2013) I. Margine et al.   JOURNAL OF VIROLOGY

Neuraminidase-Inhibiting Antibody Is a Correlate of Cross-Protection against Lethal H5N1 Influenza Virus in Ferrets Immunized with Seasonal Influenza Vaccine

(2013) S. Rockman et al.   JOURNAL OF VIROLOGY

A Mutant Influenza Virus That Uses an N1 Neuraminidase as the Receptor-Binding Protein

(2013) Kathryn A. Hooper et al.   JOURNAL OF VIROLOGY

Chimeric Hemagglutinin Influenza Virus Vaccine Constructs Elicit Broadly Protective Stalk-Specific Antibodies

(2013) F. Krammer et al.   JOURNAL OF VIROLOGY

Universal influenza virus vaccines: need for clinical trials

(2013) Florian Krammer et al.   NATURE IMMUNOLOGY

A Recombinant Viruslike Particle Influenza A (H7N9) Vaccine

(2013) Louis F. Fries et al.   NEW ENGLAND JOURNAL OF MEDICINE

One-shot vaccination with an insect cell-derived low-dose influenza A H7 virus-like particle preparation protects mice against H7N9 challenge

(2013) Miriam Klausberger et al.   VACCINE

Influenza A penetrates host mucus by cleaving sialic acids with neuraminidase

(2013) Miriam Cohen et al.   Virology Journal

Influenza virus hemagglutinin stalk-based antibodies and vaccines

(2013) Florian Krammer et al.   Current Opinion in Virology

New World Bats Harbor Diverse Influenza A Viruses

(2013) Suxiang Tong et al.   PLoS Pathogens

Immunodominance: A pivotal principle in host response to viral infections

(2012) Ali Akram et al.   CLINICAL IMMUNOLOGY

Hemagglutinin Stalk-Reactive Antibodies Are Boosted following Sequential Infection with Seasonal and Pandemic H1N1 Influenza Virus in Mice

(2012) F. Krammer et al.   JOURNAL OF VIROLOGY

Influenza Virus Neuraminidases with Reduced Enzymatic Activity That Avidly Bind Sialic Acid Receptors

(2012) X. Zhu et al.   JOURNAL OF VIROLOGY

Influenza Viruses Expressing Chimeric Hemagglutinins: Globular Head and Stalk Domains Derived from Different Subtypes

(2012) R. Hai et al.   JOURNAL OF VIROLOGY

Evolutionary History and Phylodynamics of Influenza A and B Neuraminidase (NA) Genes Inferred from Large-Scale Sequence Analyses

(2012) Jianpeng Xu et al.   PLoS One

A VLP Vaccine Induces Broad-Spectrum Cross-Protective Antibody Immunity against H5N1 and H1N1 Subtypes of Influenza A Virus

(2012) Chia-Ying Wu et al.   PLoS One

Contribution of antibody production against neuraminidase to the protection afforded by influenza vaccines

(2012) Glendie Marcelin et al.   REVIEWS IN MEDICAL VIROLOGY

Randomized comparative study of the serum antihemagglutinin and antineuraminidase antibody responses to six licensed trivalent influenza vaccines

(2012) Robert B. Couch et al.   VACCINE

Influenza M1 VLPs containing neuraminidase induce heterosubtypic cross-protection

(2012) Fu-Shi Quan et al.   VIROLOGY

Protection against a lethal H5N1 influenza challenge by intranasal immunization with virus-like particles containing 2009 pandemic H1N1 neuraminidase in mice

(2012) Judith D. Easterbrook et al.   VIROLOGY

New technologies for influenza vaccines

(2012) Philip Dormitzer et al.   Human Vaccines & Immunotherapeutics

Revisiting the 1976 "Swine Flu" Vaccine Clinical Trials: Cross-reactive Hemagglutinin and Neuraminidase Antibodies and Their Role in Protection Against the 2009 H1N1 Pandemic Virus in Mice

(2011) H. Xie et al.   CLINICAL INFECTIOUS DISEASES

Influenza viral neuraminidase: the forgotten antigen

(2011) Bert E Johansson et al.   Expert Review of Vaccines

An influenza N1 neuraminidase-specific monoclonal antibody with broad neuraminidase inhibition activity against H5N1 HPAI viruses

(2011) Yoko Shoji et al.   Human vaccines & immunotherapeutics

Influenza neuraminidase

(2011) Gillian M. Air   Influenza and Other Respiratory Viruses

A Vero Cell–Derived Whole-Virus H5N1 Vaccine Effectively Induces Neuraminidase-Inhibiting Antibodies

(2011) Richard Fritz et al.   JOURNAL OF INFECTIOUS DISEASES

Expression, purification and characterization of low-glycosylation influenza neuraminidase in α-1,6-mannosyltransferase defective Pichia pastoris

(2011) Yi-Li Yang et al.   MOLECULAR BIOLOGY REPORTS

Evidence of Infection with H4 and H11 Avian Influenza Viruses among Lebanese Chicken Growers

(2011) Ghazi Kayali et al.   PLoS One

A Contributing Role for Anti-Neuraminidase Antibodies on Immunity to Pandemic H1N1 2009 Influenza A Virus

(2011) Glendie Marcelin et al.   PLoS One

Discordant antigenic drift of neuraminidase and hemagglutinin in H1N1 and H3N2 influenza viruses

(2011) M. R. Sandbulte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Why Do Influenza Virus Subtypes Die Out? A Hypothesis

(2011) P. Palese et al.   mBio

Inactivated Seasonal Influenza Vaccines Increase Serum Antibodies to the Neuraminidase of Pandemic Influenza A(H1N1) 2009 Virus in an Age‐Dependent Manner

(2010) Glendie Marcelin et al.   JOURNAL OF INFECTIOUS DISEASES

Recombinant Soluble, Multimeric HA and NA Exhibit Distinctive Types of Protection against Pandemic Swine-Origin 2009 A(H1N1) Influenza Virus Infection in Ferrets

(2010) B. J. Bosch et al.   JOURNAL OF VIROLOGY

Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes

(2010) T. T. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative influenza vaccines made by insect cells

(2010) Florian Krammer et al.   TRENDS IN MOLECULAR MEDICINE

Transforming Growth Factor-β: Activation by Neuraminidase and Role in Highly Pathogenic H5N1 Influenza Pathogenesis

(2010) Christina M. Carlson et al.   PLoS Pathogens

Broadly Protective Monoclonal Antibodies against H3 Influenza Viruses following Sequential Immunization with Different Hemagglutinins

(2010) Taia T. Wang et al.   PLoS Pathogens

Hemagglutinin Receptor Binding Avidity Drives Influenza A Virus Antigenic Drift

(2009) S. E. Hensley et al.   SCIENCE

WHO meeting on the role of neuraminidase in inducing protective immunity against influenza infection, Vilamoura, Portugal, September 14, 2008

(2009) Rick A. Bright et al.   VACCINE

Prior infection with an H1N1 swine influenza virus partially protects pigs against a low pathogenic H5N1 avian influenza virus

(2009) Kristien Van Reeth et al.   VACCINE

A high dosage influenza vaccine induced significantly more neuraminidase antibody than standard vaccine among elderly subjects

(2009) Thomas R. Cate et al.   VACCINE

Evidence of Previous Avian Influenza Infection among US Turkey Workers

(2009) G. Kayali et al.   Zoonoses and Public Health

Insights into infectious disease in the era of Hippocrates

(2008) Georgios Pappas et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Structural Characterization of the 1918 Influenza Virus H1N1 Neuraminidase

(2008) X. Xu et al.   JOURNAL OF VIROLOGY

FDA/NIH/WHO public workshop on immune correlates of protection against influenza A viruses in support of pandemic vaccine development, Bethesda, Maryland, US, December 10–11, 2007

(2008) Maryna Eichelberger et al.   VACCINE