Cannabinoid Receptor 1 Participates in Liver Inflammation by Promoting M1 Macrophage Polarization via RhoA/NF-κB p65 and ERK1/2 Pathways, Respectively, in Mouse Liver Fibrogenesis

An endoplasmic reticulum protein, Nogo-B, facilitates alcoholic liver disease through regulation of kupffer cell polarization

(2017) Jin-Kyu Park et al.   HEPATOLOGY

Pathogenesis of Kupffer Cells in Cholestatic Liver Injury

(2016) Keisaku Sato et al.   AMERICAN JOURNAL OF PATHOLOGY

Cannabinoids and autoimmune diseases: A systematic review

(2016) Valeria Katchan et al.   AUTOIMMUNITY REVIEWS

Cannabinoid receptor signaling regulates liver development and metabolism

(2016) Leah Y. Liu et al.   DEVELOPMENT

DPP-4 Inhibition by Linagliptin Attenuates Obesity-Related Inflammation and Insulin Resistance by Regulating M1/M2 Macrophage Polarization

(2016) Fen Zhuge et al.   DIABETES

Endocannabinoid regulation of β -cell functions: implications for glycaemic control and diabetes

(2016) T. Jourdan et al.   DIABETES OBESITY & METABOLISM

Bisphenol A Induces Fatty Liver by an Endocannabinoid-Mediated Positive Feedback Loop

(2016) Andrea Martella et al.   ENDOCRINOLOGY

Opposite roles of cannabinoid receptors 1 and 2 in hepatocarcinogenesis

(2016) Ki-Tae Suk et al.   GUT

Immunology in the liver — from homeostasis to disease

(2016) Felix Heymann et al.   Nature Reviews Gastroenterology & Hepatology

The cannabinoid WIN 55,212-2 prevents neuroendocrine differentiation of LNCaP prostate cancer cells

(2016) C Morell et al.   PROSTATE CANCER AND PROSTATIC DISEASES

Novel Action of Carotenoids on Non-Alcoholic Fatty Liver Disease: Macrophage Polarization and Liver Homeostasis

(2016) Yinhua Ni et al.   Nutrients

Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms

(2015) Bani Mukhopadhyay et al.   HEPATOLOGY

Liver-Resident Macrophage Necroptosis Orchestrates Type 1 Microbicidal Inflammation and Type-2-Mediated Tissue Repair during Bacterial Infection

(2015) Camille Blériot et al.   IMMUNITY

Cannabinoid receptor 1 but not 2 mediates macrophage phagocytosis by G(α)i/o/RhoA/ROCK signaling pathway

(2015) Ping Mai et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Endocannabinoid System Contributes to Liver Injury and Inflammation by Activation of Bone Marrow–Derived Monocytes/Macrophages in a CB1-Dependent Manner

(2015) Ping Mai et al.   JOURNAL OF IMMUNOLOGY

Effects of Cannabinoids on T-cell Function and Resistance to Infection

(2015) Toby K. Eisenstein et al.   Journal of Neuroimmune Pharmacology

Cannabinoid receptor 1 is a major mediator of renal fibrosis

(2015) Lola Lecru et al.   KIDNEY INTERNATIONAL

Molecular and epigenetic basis of macrophage polarized activation

(2015) Chiara Porta et al.   SEMINARS IN IMMUNOLOGY

The Endocannabinoid System: Pivotal Orchestrator of Obesity and Metabolic Disease

(2015) Wilfrid Mazier et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Macrophages During the Fibrotic Process: M2 as Friend and Foe

(2015) Tarcio Teodoro Braga et al.   Frontiers in Immunology

Macrophage heterogeneity in liver injury and fibrosis

(2014) Frank Tacke et al.   JOURNAL OF HEPATOLOGY

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

(2014) Nan Wang et al.   Frontiers in Immunology

Cannabinoid 1 receptors are critical for the innate immune response to TLR4 stimulation

(2013) Marnie Duncan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

A Direct In Vivo RNAi Screen Identifies MKK4 as a Key Regulator of Liver Regeneration

(2013) Torsten Wuestefeld et al.   CELL

Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasingde novosynthesis of long-chain ceramides

(2013) Resat Cinar et al.   HEPATOLOGY

Macrophage plasticity and polarization in liver homeostasis and pathology

(2013) Antonio Sica et al.   HEPATOLOGY

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

(2013) Tony Jourdan et al.   NATURE MEDICINE

Endogenous cannabinoids revisited: A biochemistry perspective

(2013) B.M. Fonseca et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Cannabinoid 1 Receptor Promotes Cardiac Dysfunction, Oxidative Stress, Inflammation, and Fibrosis in Diabetic Cardiomyopathy

(2012) M. Rajesh et al.   DIABETES

Macrophage polarization and plasticity in health and disease

(2012) Subhra K. Biswas et al.   IMMUNOLOGIC RESEARCH

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage plasticity and polarization in tissue repair and remodelling

(2012) Alberto Mantovani et al.   JOURNAL OF PATHOLOGY

Immunity and early pregnancy events: are endocannabinoids the missing link?

(2012) Katerina N. Bambang et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice

(2011) Alexandre Louvet et al.   HEPATOLOGY

Endocannabinoids in liver disease

(2010) Joseph Tam et al.   HEPATOLOGY

Alternative activation of macrophages: Immune function and cellular biology

(2009) Audrey Varin et al.   IMMUNOBIOLOGY

Signal transduction of the CB1 cannabinoid receptor

(2009) Gábor Turu et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology