Interleukin-7 Induces Osteoclast Formation via STAT5, Independent of Receptor Activator of NF-kappaB Ligand

Targeting inflammation in the prevention of cardiovascular disease in patients with inflammatory arthritis

(2016) Jiayun Shen et al.   Translational Research

STAT5 is a key transcription factor for IL-3-mediated inhibition of RANKL-induced osteoclastogenesis

(2016) Jongwon Lee et al.   Scientific Reports

Topographic characterisation of dental implants for commercial use

(2016) A Mendoza-Arnau et al.   Medicina Oral Patologia Oral y Cirugia Bucal

RANK-Independent Osteoclast Formation and Bone Erosion in Inflammatory Arthritis

(2016) William O'Brien et al.   Arthritis & Rheumatology

Effect of denosumab on Japanese patients with rheumatoid arthritis: a dose–response study of AMG 162 (Denosumab) in patients withRheumatoId arthritis on methotrexate toValidate inhibitory effect on boneErosion (DRIVE)—a 12-month, multicentre, randomised, double-blind, placebo-controlled, phase II clinical trial

(2015) Tsutomu Takeuchi et al.   ANNALS OF THE RHEUMATIC DISEASES

RANKL expressed on synovial fibroblasts is primarily responsible for bone erosions during joint inflammation

(2015) Lynett Danks et al.   ANNALS OF THE RHEUMATIC DISEASES

RBP-J imposes a requirement for ITAM-mediated costimulation of osteoclastogenesis

(2014) Susan Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Tofacitinib versus Methotrexate in Rheumatoid Arthritis

(2014) Eun Bong Lee et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bone resorption is regulated by cell-autonomous negative feedback loop of Stat5–Dusp axis in the osteoclast

(2013) Jun Hirose et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Reciprocal Activation of CD4+ T Cells and Synovial Fibroblasts by Stromal Cell-Derived Factor 1 Promotes RANKL Expression and Osteoclastogenesis in Rheumatoid Arthritis

(2013) Hae-Rim Kim et al.   Arthritis & Rheumatology

Rheumatoid and pyrophosphate arthritis synovial fibroblasts induce osteoclastogenesis independently of RANKL, TNF and IL-6

(2012) Tiffany J. Dickerson et al.   JOURNAL OF AUTOIMMUNITY

Characterization of Effector Memory CD8+ T Cells in the Synovial Fluid of Rheumatoid Arthritis

(2012) Bon-A Cho et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Interleukin-7-aggravated joint inflammation and tissue destruction in collagen-induced arthritis is associated with T-cell and B-cell activation

(2012) Sarita AY Hartgring et al.   ARTHRITIS RESEARCH & THERAPY

Disorders of Bone Remodeling

(2011) Xu Feng et al.   Annual Review of Pathology-Mechanisms of Disease

Characterization of interleukin-7 and interleukin-7 receptor in the pathogenesis of rheumatoid arthritis

(2011) Sarah R. Pickens et al.   ARTHRITIS AND RHEUMATISM

Blockade of the interleukin-7 receptor inhibits collagen-induced arthritis and is associated with reduction of T cell activity and proinflammatory mediators

(2010) Sarita A. Y. Hartgring et al.   ARTHRITIS AND RHEUMATISM

RANKL-independent human osteoclast formation with APRIL, BAFF, NGF, IGF I and IGF II

(2010) F. Hemingway et al.   BONE

Elevated expression of interleukin-7 receptor in inflamed joints mediates interleukin-7-induced immune activation in rheumatoid arthritis

(2009) Sarita A. Y. Hartgring et al.   ARTHRITIS AND RHEUMATISM

Cytokine-controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: Fibroblast-mediated pathologic bone resorption

(2008) Miklos Tunyogi-Csapo et al.   ARTHRITIS AND RHEUMATISM

Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: A twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial

(2008) Stanley B. Cohen et al.   ARTHRITIS AND RHEUMATISM

Discovery of Chromone-Based Inhibitors of the Transcription Factor STAT5

(2008) Judith Müller et al.   CHEMBIOCHEM

Interleukin-7 in rheumatoid arthritis

(2008) S. M. Churchman et al.   RHEUMATOLOGY