Titania-Coated Gold Nano-Bipyramids for Blocking Autophagy Flux and Sensitizing Cancer Cells to Proteasome Inhibitor-Induced Death

Regulation of lysosomal dynamics and autophagy by CTSB/cathepsin B

(2016) Si Ming Man et al.   Autophagy

Reactive oxygen species acts as executor in radiation enhancement and autophagy inducing by AgNPs

(2016) Hao Wu et al.   BIOMATERIALS

Therapeutic hyperthermia: The old, the new, and the upcoming

(2016) Matthew Mallory et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Iron Oxide Nanoparticles Induce Autophagosome Accumulation through Multiple Mechanisms: Lysosome Impairment, Mitochondrial Damage, and ER Stress

(2016) Xudong Zhang et al.   MOLECULAR PHARMACEUTICS

pH-Sensitive Polymeric Nanoparticles Modulate Autophagic Effect via Lysosome Impairment

(2016) Yao-Xin Lin et al.   Small

Local hyperthermia combined with radiotherapy and-/or chemotherapy: Recent advances and promises for the future

(2015) N.R. Datta et al.   CANCER TREATMENT REVIEWS

Production of Monodisperse Gold Nanobipyramids with Number Percentages Approaching 100% and Evaluation of Their Plasmonic Properties

(2015) Qian Li et al.   Advanced Optical Materials

Enhanced proteotoxic stress: one of the contributors for hyperthermic potentiation of the proteasome inhibitor bortezomib using magnetic nanoparticles

(2015) Merlis P. Alvarez-Berrios et al.   Biomaterials Science

Interference in Autophagosome Fusion by Rare Earth Nanoparticles Disrupts Autophagic Flux and Regulation of an Interleukin-1β Producing Inflammasome

(2014) Ruibin Li et al.   ACS Nano

Tuning Cell Autophagy by Diversifying Carbon Nanotube Surface Chemistry

(2014) Ling Wu et al.   ACS Nano

Ceria Nanoparticles Stabilized by Organic Surface Coatings Activate the Lysosome-Autophagy System and Enhance Autophagic Clearance

(2014) Wensi Song et al.   ACS Nano

Cellular Mechanisms of Endoplasmic Reticulum Stress Signaling in Health and Disease. 2. Protein misfolding and ER stress

(2014) Joseph E. Chambers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A cathepsin L-specific inhibitor preferentially inhibits degradation of autophagosomal LC3 and GABARAP in HeLa and Huh-7 cells

(2014) Takashi Ueno et al.   Autophagy

Combined autophagy and proteasome inhibition

(2014) Dan T Vogl et al.   Autophagy

Curcusone D, a novel ubiquitin–proteasome pathway inhibitor via ROS-induced DUB inhibition, is synergistic with bortezomib against multiple myeloma cell growth

(2014) Mei-Na Cao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Quantitative electrochemical detection of cathepsin B activity in complex tissue lysates using enhanced AC voltammetry at carbon nanofiber nanoelectrode arrays

(2014) Luxi Z. Swisher et al.   BIOSENSORS & BIOELECTRONICS

Efficacy of therapy with bortezomib in solid tumors: a review based on 32 clinical trials

(2014) Zebo Huang et al.   Future Oncology

Cellular uptake behaviour, photothermal therapy performance, and cytotoxicity of gold nanorods with various coatings

(2014) Xiao-Ming Zhu et al.   Nanoscale

Silica nanoparticles enhance autophagic activity, disturb endothelial cell homeostasis and impair angiogenesis

(2014) Junchao Duan et al.   Particle and Fibre Toxicology

Expression Analysis of All Protease Genes Reveals Cathepsin K to Be Overexpressed in Glioblastoma

(2014) Urška Verbovšek et al.   PLoS One

New directions in ER stress-induced cell death

(2013) Susan E. Logue et al.   APOPTOSIS

The role of elevated autophagy on the synaptic plasticity impairment caused by CdSe/ZnS quantum dots

(2013) Liang Chen et al.   BIOMATERIALS

Autophagy-Mediated Tumor Promotion

(2013) Jessie Yanxiang Guo et al.   CELL

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cathepsin-mediated regulation of autophagy in saposin C deficiency

(2012) Massimo Tatti et al.   Autophagy

Gold nanorods and their plasmonic properties

(2012) Huanjun Chen et al.   CHEMICAL SOCIETY REVIEWS

Reduced cathepsins B and D cause impaired autophagic degradation that can be almost completely restored by overexpression of these two proteases in Sap C-deficient fibroblasts

(2012) M. Tatti et al.   HUMAN MOLECULAR GENETICS

Tuning the autophagy-inducing activity of lanthanide-based nanocrystals through specific surface-coating peptides

(2012) Yunjiao Zhang et al.   NATURE MATERIALS

Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity

(2012) Stephan T Stern et al.   Particle and Fibre Toxicology

Stress management at the ER: Regulators of ER stress-induced apoptosis

(2012) Adrienne M. Gorman et al.   PHARMACOLOGY & THERAPEUTICS

Exposure to Titanium Dioxide Nanoparticles Induces Autophagy in Primary Human Keratinocytes

(2012) Yun Zhao et al.   Small

Gold Nanoparticles Induce Autophagosome Accumulation through Size-Dependent Nanoparticle Uptake and Lysosome Impairment

(2011) Xiaowei Ma et al.   ACS Nano

Retinal Toxicity Associated With Hydroxychloroquine and Chloroquine

(2011) Michel Michaelides   ARCHIVES OF OPHTHALMOLOGY

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Specific Cell-Permeable Inhibitor of Proteasome Trypsin-like Sites Selectively Sensitizes Myeloma Cells to Bortezomib and Carfilzomib

(2011) Anne C. Mirabella et al.   CHEMISTRY & BIOLOGY

Targeting the pro-death and pro-survival functions of autophagy as novel therapeutic strategies in cancer

(2010) Kevin Dalby et al.   Autophagy

Processing of autophagic protein LC3 by the 20S proteasome

(2010) Zhonghua Gao et al.   Autophagy

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Gold nanostructures: a class of multifunctional materials for biomedical applications

(2010) Claire M. Cobley et al.   CHEMICAL SOCIETY REVIEWS

Specialized roles for cysteine cathepsins in health and disease

(2010) Jochen Reiser et al.   JOURNAL OF CLINICAL INVESTIGATION

Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets

(2010) Lynn Bedford et al.   NATURE REVIEWS DRUG DISCOVERY

Selective Inhibitor of Proteasome's Caspase-like Sites Sensitizes Cells to Specific Inhibition of Chymotrypsin-like Sites

(2009) Matthew Britton et al.   CHEMISTRY & BIOLOGY

Combination of hyperthermia and bortezomib results in additive killing in mantle cell lymphoma cells

(2009) Valeria Milani et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Characterization of the ubiquitin–proteasome system in bortezomib-adapted cells

(2009) T Rückrich et al.   LEUKEMIA

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates

(2009) Viktor I. Korolchuk et al.   MOLECULAR CELL