Targets of Neutrophil Influx and Weaponry: Therapeutic Opportunities for Chronic Obstructive Airway Disease
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Title
Targets of Neutrophil Influx and Weaponry: Therapeutic Opportunities for Chronic Obstructive Airway Disease
Authors
Keywords
-
Journal
Journal of Immunology Research
Volume 2017, Issue -, Pages 1-13
Publisher
Hindawi Limited
Online
2017-05-18
DOI
10.1155/2017/5273201
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Note: Only part of the references are listed.- Idelalisib given front-line for treatment of chronic lymphocytic leukemia causes frequent immune-mediated hepatotoxicity
- (2016) B. L. Lampson et al. BLOOD
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- (2016) Argyris Tzouvelekis et al. RESPIROLOGY
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- (2016) Thomas K. Wright et al. RESPIROLOGY
- The chemokine CXCR2 antagonist (AZD5069) preserves neutrophil-mediated host immunity in non-human primates
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- Efficacy and safety of a CXCR2 antagonist, AZD5069, in patients with uncontrolled persistent asthma: a randomised, double-blind, placebo-controlled trial
- (2016) Paul M O'Byrne et al. Lancet Respiratory Medicine
- NET Confusion
- (2016) Natalia Malachowa et al. Frontiers in Immunology
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- (2015) Stephen I. Rennard et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- PI3K signalling in inflammation
- (2015) P.T. Hawkins et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The effect of a selective CXCR2 antagonist (AZD5069) on human blood neutrophil count and innate immune functions
- (2015) Stipo Jurcevic et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- A randomised, placebo-controlled study of the CXCR2 antagonist AZD5069 in bronchiectasis
- (2015) Anthony De Soyza et al. EUROPEAN RESPIRATORY JOURNAL
- A summary of the new GINA strategy: a roadmap to asthma control
- (2015) Helen K. Reddel et al. EUROPEAN RESPIRATORY JOURNAL
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- (2015) P. L. B. Bruijnzeel et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Free DNA in Cystic Fibrosis Airway Fluids Correlates with Airflow Obstruction
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- (2013) E. Sapey et al. BLOOD
- The Electrophoretic α1-Globulin Pattern of Serum in α1-Antitrypsin Deficiency
- (2013) Carl-Bertil Laurell et al. COPD-Journal of Chronic Obstructive Pulmonary Disease
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- (2013) Sardar M. Z. Uddin et al. PLoS One
- Phase II study of a neutrophil elastase inhibitor (AZD9668) in patients with bronchiectasis
- (2013) Robert Stockley et al. RESPIRATORY MEDICINE
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- (2013) Olivia Z. Cheng et al. Frontiers in Immunology
- Neutrophil Elastase Degrades Cystic Fibrosis Transmembrane Conductance Regulator via Calpains and Disables Channel FunctionIn VitroandIn Vivo
- (2012) Mathieu Le Gars et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
- (2012) Jørgen Vestbo et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Global asthma prevalence in adults: findings from the cross-sectional world health survey
- (2012) Teresa To et al. BMC PUBLIC HEALTH
- Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils: a randomized, placebo-controlled clinical trial
- (2012) P. Nair et al. CLINICAL AND EXPERIMENTAL ALLERGY
- A Randomised, Placebo-Controlled, Dose-Finding Study Of AZD9668, An Oral Inhibitor of Neutrophil Elastase, in Patients with Chronic Obstructive Pulmonary Disease Treated with Tiotropium
- (2012) Claus Vogelmeier et al. COPD-Journal of Chronic Obstructive Pulmonary Disease
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- (2012) Nicola J. Sinden et al. EUROPEAN RESPIRATORY JOURNAL
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- (2012) J. Stuart Elborn et al. EUROPEAN RESPIRATORY JOURNAL
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- (2012) Suyoung Bae et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Ronald Dahl et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- G-CSF-mediated thrombopoietin release triggers neutrophil motility and mobilization from bone marrow via induction of Cxcr2 ligands
- (2011) A. Kohler et al. BLOOD
- SB-656933, a novel CXCR2 selective antagonist, inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans
- (2011) Aili L. Lazaar et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
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- (2008) D J McKeon et al. THORAX
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