MicroRNAs Regulate Thymic Epithelium in Age-Related Thymic Involution via Down- or Upregulation of Transcription Factors

A Fine-Tune Role of Mir-125a-5p on Foxn1 During Age-Associated Changes in the Thymus

(2017) Minwen Xu et al.   Aging and Disease

MicroRNA-181a-5p enhances cell proliferation in medullary thymic epithelial cells via regulating TGF-β signaling

(2016) Dongguang Guo et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Genetic and Epigenetic Silencing of MicroRNA-203 Enhances ABL1 and BCR - ABL1 Oncogene Expression

(2016) María J. Bueno et al.   CANCER CELL

MicroRNA Biogenesis and Hedgehog-Patched Signaling Cooperate to Regulate an Important Developmental Transition in Granule Cell Development

(2016) L. Constantin et al.   GENETICS

The tumor-suppressive microRNA-23b/27b cluster regulates the MET oncogene in oral squamous cell carcinoma

(2016) Ichiro Fukumoto et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

MicroRNA-205 Maintains T Cell Development following Stress by RegulatingForkhead Box N1and Selected Chemokines

(2016) Ashley R. Hoover et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional programs that control expression of the autoimmune regulator gene Aire

(2016) Yonatan Herzig et al.   NATURE IMMUNOLOGY

MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR

(2016) Claudia J. Krause et al.   Oncotarget

ΔNp63α and microRNAs: leveraging the epithelial-mesenchymal transition

(2016) Andrew J. Stacy et al.   Oncotarget

Aire Downregulation Is Associated with Changes in the Posttranscriptional Control of Peripheral Tissue Antigens in Medullary Thymic Epithelial Cells

(2016) Ernna H. Oliveira et al.   Frontiers in Immunology

MicroRNA-454 functions as an oncogene by regulating PTEN in uveal melanoma

(2015) Lei Sun et al.   FEBS LETTERS

Overexpression of microRNA-16 declines cellular growth, proliferation and induces apoptosis in human breast cancer cells

(2015) Naser Mobarra et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Thymic Involution Perturbs Negative Selection Leading to Autoreactive T Cells That Induce Chronic Inflammation

(2015) Brandon D. Coder et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-20b-5p functions as a tumor suppressor in renal cell carcinoma by regulating cellular proliferation, migration and apoptosis

(2015) YIFAN LI et al.   Molecular Medicine Reports

Aire controls gene expression in the thymic epithelium with ordered stochasticity

(2015) Matthew Meredith et al.   NATURE IMMUNOLOGY

Identification of MiR-205 As a MicroRNA That Is Highly Expressed in Medullary Thymic Epithelial Cells

(2015) Imran S. Khan et al.   PLoS One

Functional relevance of “seed” and “non-seed” sequences in microRNA-mediated promotion ofC. elegansdevelopmental progression

(2015) Huibin Zhang et al.   RNA

MicroRNA-199b Modulates Vascular Cell Fate During iPS Cell Differentiation by Targeting the Notch Ligand Jagged1 and Enhancing VEGF Signaling

(2015) Ting Chen et al.   STEM CELLS

Oncogenic microRNA-142-3p is associated with cellular migration, proliferation and apoptosis in renal cell carcinoma

(2015) YIFAN LI et al.   Oncology Letters

Thymic involution beyond T-cell insufficiency

(2015) Brandon Coder et al.   Oncotarget

Post-transcriptional Regulation of Keratinocyte Progenitor Cell Expansion, Differentiation and Hair Follicle Regression by miR-22

(2015) Shukai Yuan et al.   PLoS Genetics

Editorial: The Role of Aire, microRNAs and Cell–Cell Interactions on Thymic Architecture and Induction of Tolerance

(2015) Geraldo Aleixo Passos et al.   Frontiers in Immunology

The Thymic Orchestration Involving Aire, miRNAs, and Cell–Cell Interactions during the Induction of Central Tolerance

(2015) Geraldo Aleixo Passos et al.   Frontiers in Immunology

Maternal high-fat diet consumption modulates hepatic lipid metabolism and microRNA-122 (miR-122) and microRNA-370 (miR-370) expression in offspring

(2014) R. O. Benatti et al.   BRITISH JOURNAL OF NUTRITION

Canonical microRNAs in thymic epithelial cells promote central tolerance

(2014) Imran S. Khan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

microRNA management of NK-cell developmental and functional programs

(2014) Jeffrey W. Leong et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The impact of microRNA expression on cellular proliferation

(2014) Divya Lenkala et al.   HUMAN GENETICS

STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors

(2014) Liufu Deng et al.   IMMUNITY

miR-155 Promotes T Follicular Helper Cell Accumulation during Chronic, Low-Grade Inflammation

(2014) Ruozhen Hu et al.   IMMUNITY

WNT Signaling Suppression in the Senescent Human Thymus

(2014) Sara Ferrando-Martínez et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

MicroRNA-21 (miR-21) Regulates Cellular Proliferation, Invasion, Migration, and Apoptosis by Targeting PTEN, RECK and Bcl-2 in Lung Squamous Carcinoma, Gejiu City, China

(2014) Long-feng Xu et al.   PLoS One

Induced multipotency in adult keratinocytes through down-regulation ofΔNp63orDGCR8

(2014) Deepavali Chakravarti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-18b and miR-518b Target FOXN1 During Epithelial Lineage Differentiation in Pluripotent Cells

(2014) Ritu Kushwaha et al.   STEM CELLS AND DEVELOPMENT

Re-expression of microRNA-150 induces EBV-positive Burkitt lymphoma differentiation by modulating c-Mybin vitro

(2013) Shaohong Chen et al.   CANCER SCIENCE

Immunosenescence: a product of the environment?

(2013) Dong-Ming Su et al.   CURRENT OPINION IN IMMUNOLOGY

Rapid and widespread suppression of self-renewal by microRNA-203 during epidermal differentiation

(2013) S. J. Jackson et al.   DEVELOPMENT

Human adipose microRNA-221 is upregulated in obesity and affects fat metabolism downstream of leptin and TNF-α

(2013) A. Meerson et al.   DIABETOLOGIA

An evolutionarily conserved mutual interdependence between Aire and microRNAs in promiscuous gene expression

(2013) Olga Ucar et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulation of human autoimmune regulator (AIRE) gene translation by miR-220b

(2013) Tomohito Matsuo et al.   GENE

Immune Cell Infiltration in Malignant Middle Cerebral Artery Infarction: Comparison with Transient Cerebral Ischemia

(2013) Hannah X Chu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression

(2013) Phillip M. Garfin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of the p63-FoxN1 regulatory axis in thymic epithelial cell homeostasis during aging

(2013) P Burnley et al.   Cell Death & Disease

FOXN1: A Master Regulator Gene of Thymic Epithelial Development Program

(2013) Rosa Romano et al.   Frontiers in Immunology

MicroRNA-203 regulates caveolin-1 in breast tissue during caloric restriction

(2012) Ulf Andersson Ørom et al.   CELL CYCLE

Autoimmune regulator (Aire) controls the expression of microRNAs in medullary thymic epithelial cells

(2012) Claudia Macedo et al.   IMMUNOBIOLOGY

MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages

(2012) Maliheh Nazari-Jahantigh et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNAs Control the Maintenance of Thymic Epithelia and Their Competence for T Lineage Commitment and Thymocyte Selection

(2012) S. Zuklys et al.   JOURNAL OF IMMUNOLOGY

The miR-17 Family Links p63 Protein to MAPK Signaling to Promote the Onset of Human Keratinocyte Differentiation

(2012) Ning Wu et al.   PLoS One

p63-microRNA feedback in keratinocyte senescence

(2012) P. Rivetti di Val Cervo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The MicroRNA mir-71 Inhibits Calcium Signaling by Targeting the TIR-1/Sarm1 Adaptor Protein to Control Stochastic L/R Neuronal Asymmetry in C. elegans

(2012) Yi-Wen Hsieh et al.   PLoS Genetics

iASPP/p63 autoregulatory feedback loop is required for the homeostasis of stratified epithelia

(2011) Anissa Chikh et al.   EMBO JOURNAL

miR-146ais a significant brake on autoimmunity, myeloproliferation, and cancer in mice

(2011) Mark P. Boldin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor

(2011) Aikaterini S Papadopoulou et al.   NATURE IMMUNOLOGY

Dynamic Modulation of Thymic MicroRNAs in Response to Stress

(2011) Serkan Belkaya et al.   PLoS One

NF- B dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies

(2011) J. L. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Declining expression of a single epithelial cell-autonomous gene accelerates age-related thymic involution

(2010) Liguang Sun et al.   AGING CELL

p63in Epithelial Survival, Germ Cell Surveillance, and Neoplasia

(2010) Christopher P. Crum et al.   Annual Review of Pathology-Mechanisms of Disease

The guardians of the genome (p53, TA-p73, and TA-p63) are regulators of tumor suppressor miRNAs network

(2010) Lakshmanane Boominathan   CANCER AND METASTASIS REVIEWS

Reversal of aging by NFκB blockade

(2010) Adam S. Adler et al.   CELL CYCLE

The expression of microRNA-203 during human skin morphogenesis

(2010) Tianling Wei et al.   EXPERIMENTAL DERMATOLOGY

MicroRNA-155 Promotes Autoimmune Inflammation by Enhancing Inflammatory T Cell Development

(2010) Ryan M. O'Connell et al.   IMMUNITY

Transcriptional Repression of miR-34 Family Contributes to p63-Mediated Cell Cycle Progression in Epidermal Cells

(2010) Dario Antonini et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

(2010) Xiaohua Su et al.   NATURE

The Tumor Suppressors p53, p63, and p73 Are Regulators of MicroRNA Processing Complex

(2010) Lakshmanane Boominathan   PLoS One

Thymopoiesis in mice depends on a Foxn1-positive thymic epithelial cell lineage

(2010) T. Corbeaux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stem Cells in Toxicology: Fundamental Biology and Practical Considerations

(2010) K.-S. Kang et al.   TOXICOLOGICAL SCIENCES

Postnatal Tissue-specific Disruption of Transcription Factor FoxN1 Triggers Acute Thymic Atrophy

(2009) Lili Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stabilized  -Catenin in Thymic Epithelial Cells Blocks Thymus Development and Function

(2009) S. Zuklys et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: The Foxp3 Target miR-155 Contributes to the Development of Regulatory T Cells

(2009) S. Kohlhaas et al.   JOURNAL OF IMMUNOLOGY

mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells

(2009) C. Chen et al.   Science Signaling

Thymic involution and immune reconstitution

(2009) Heather E. Lynch et al.   TRENDS IN IMMUNOLOGY

Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner

(2008) L. Chen et al.   BLOOD

miR-203 represses ‘stemness’ by repressing ΔNp63

(2008) A M Lena et al.   CELL DEATH AND DIFFERENTIATION

A skin microRNA promotes differentiation by repressing ‘stemness’

(2008) Rui Yi et al.   NATURE