The Tumor Suppressors p53, p63, and p73 Are Regulators of MicroRNA Processing Complex

Immunofluorescence-based screening identifies germ cell associated microRNA 302 as an antagonist to p63 expression

(2011) Andreas Scheel et al.   CELL CYCLE

Stable expression of miR-200c alone is sufficient to regulate TCF8 (ZEB1) and restore E-cadherin expression

(2011) Gregory J. Hurteau et al.   CELL CYCLE

Prognostic value of Dicer expression in human breast cancers and association with the mesenchymal phenotype

(2009) G Grelier et al.   BRITISH JOURNAL OF CANCER

The TRIM-NHL Protein TRIM32 Activates MicroRNAs and Prevents Self-Renewal in Mouse Neural Progenitors

(2009) Jens C. Schwamborn et al.   CELL

TUT4 in Concert with Lin28 Suppresses MicroRNA Biogenesis through Pre-MicroRNA Uridylation

(2009) Inha Heo et al.   CELL

Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells

(2009) Yohei Shimono et al.   CELL

miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-α in human breast cancer cells

(2009) R Spizzo et al.   CELL DEATH AND DIFFERENTIATION

TAp63 Prevents Premature Aging by Promoting Adult Stem Cell Maintenance

(2009) Xiaohua Su et al.   Cell Stem Cell

The microRNA miR-92 increases proliferation of myeloid cells and by targeting p63 modulates the abundance of its isoforms

(2009) Isabella Manni et al.   FASEB JOURNAL

Disruption of Dicer1 Induces Dysregulated Fetal Gene Expression and Promotes Hepatocarcinogenesis

(2009) Shigeki Sekine et al.   GASTROENTEROLOGY

The NF90-NF45 Complex Functions as a Negative Regulator in the MicroRNA Processing Pathway

(2009) S. Sakamoto et al.   MOLECULAR AND CELLULAR BIOLOGY

CRD-BP Protects the Coding Region of βTrCP1 mRNA from miR-183-Mediated Degradation

(2009) Irina Elcheva et al.   MOLECULAR CELL

The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2

(2009) Agnieszka Rybak et al.   NATURE CELL BIOLOGY

A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function

(2009) Sonia A Melo et al.   NATURE GENETICS

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells

(2009) John P Hagan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

MiR-107 and MiR-185 Can Induce Cell Cycle Arrest in Human Non Small Cell Lung Cancer Cell Lines

(2009) Yukari Takahashi et al.   PLoS One

p53 represses c-Myc through induction of the tumor suppressor miR-145

(2009) M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DICER1 Mutations in Familial Pleuropulmonary Blastoma

(2009) D. A. Hill et al.   SCIENCE

Dissecting microregulation of a master regulatory network

(2008) Amit U Sinha et al.   BMC GENOMICS

A Requirement for DICER to Maintain Full Promoter CpG Island Hypermethylation in Human Cancer Cells

(2008) A. H. Ting et al.   CANCER RESEARCH

MicroRNA-21 Targets a Network of Key Tumor-Suppressive Pathways in Glioblastoma Cells

(2008) T. Papagiannakopoulos et al.   CANCER RESEARCH

let-7 regulates Dicer expression and constitutes a negative feedback loop

(2008) Shogo Tokumaru et al.   CARCINOGENESIS

Hmga2 Promotes Neural Stem Cell Self-Renewal in Young but Not Old Mice by Reducing p16Ink4a and p19Arf Expression

(2008) Jinsuke Nishino et al.   CELL

WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis

(2008) Y Li et al.   CELL DEATH AND DIFFERENTIATION

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

(2008) Ulrike Burk et al.   EMBO REPORTS

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

(2008) R. Tomasini et al.   GENES & DEVELOPMENT

Decreased Dicer expression elicits DNA damage and up-regulation of MICA and MICB

(2008) Kai-Fu Tang et al.   JOURNAL OF CELL BIOLOGY

Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells

(2008) Rajini Mudhasani et al.   JOURNAL OF CELL BIOLOGY

Nuclear Factor 45 (NF45) Is a Regulatory Subunit of Complexes with NF90/110 Involved in Mitotic Control

(2008) D. Guan et al.   MOLECULAR AND CELLULAR BIOLOGY

A Gene Signature-Based Approach Identifies mTOR as a Regulator of p73

(2008) J. M. Rosenbluth et al.   MOLECULAR AND CELLULAR BIOLOGY

Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA

(2008) Inha Heo et al.   MOLECULAR CELL

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

A skin microRNA promotes differentiation by repressing ‘stemness’

(2008) Rui Yi et al.   NATURE

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

(2008) Agnieszka Rybak et al.   NATURE CELL BIOLOGY

MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells

(2008) Lasse Sinkkonen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Distinct populations of tumor-initiating cells derived from a tumor generated by rat mammary cancer stem cells

(2008) I. Zucchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence

(2008) J. J. Forman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure

(2008) J.-F. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

(2008) M. A. Newman et al.   RNA