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Title
Targeting MDM4 Splicing in Cancers
Authors
Keywords
-
Journal
Genes
Volume 8, Issue 2, Pages 82
Publisher
MDPI AG
Online
2017-02-21
DOI
10.3390/genes8020082
References
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Note: Only part of the references are listed.- TP53 mutations emerge with HDM2 inhibitor SAR405838 treatment in de-differentiated liposarcoma
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- The spliceosome is a therapeutic vulnerability in MYC-driven cancer
- (2015) Tiffany Y.-T. Hsu et al. NATURE
- MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis
- (2015) Cheryl M. Koh et al. NATURE
- MDMX exerts its oncogenic activity via suppression of retinoblastoma protein
- (2015) H Zhang et al. ONCOGENE
- Inhibition of vemurafenib-resistant melanoma by interference with pre-mRNA splicing
- (2015) Maayan Salton et al. Nature Communications
- Semi-supervised Learning Predicts Approximately One Third of the Alternative Splicing Isoforms as Functional Proteins
- (2015) Yanqi Hao et al. Cell Reports
- Mice engineered for an obligatory Mdm4 exon skipping express higher levels of the Mdm4-S isoform but exhibit increased p53 activity
- (2014) B Bardot et al. ONCOGENE
- Mdmx promotes genomic instability independent of p53 and Mdm2
- (2014) A M Carrillo et al. ONCOGENE
- SRp20: An overview of its role in human diseases
- (2013) Claudia Corbo et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The functional consequences of intron retention: Alternative splicing coupled to NMD as a regulator of gene expression
- (2013) Ying Ge et al. BIOESSAYS
- Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery
- (2013) M. Bezzi et al. GENES & DEVELOPMENT
- Mdm4 loss in mice expressing a p53 hypomorph alters tumor spectrum without improving survival
- (2013) M Fang et al. ONCOGENE
- MDMX contains an autoinhibitory sequence element
- (2013) M. Bista et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutant Mice Lacking the p53 C-Terminal Domain Model Telomere Syndromes
- (2013) Iva Simeonova et al. Cell Reports
- Alternate Splicing of the p53 Inhibitor HDMX Offers a Superior Prognostic Biomarker than p53 Mutation in Human Cancer
- (2012) Kristiaan Lenos et al. CANCER RESEARCH
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- A Stapled p53 Helix Overcomes HDMX-Mediated Suppression of p53
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- The Spliceosome: Design Principles of a Dynamic RNP Machine
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- (2008) Andrea Prodosmo et al. JOURNAL OF MOLECULAR MEDICINE-JMM
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