Interference with Ca2+-Dependent Proteolysis Does Not Alter the Course of Muscle Wasting in Experimental Cancer Cachexia

Endoplasmic Reticulum Stress, Calcium Dysregulation and Altered Protein Translation: Intersection of Processes That Contribute to Cancer Cachexia Induced Skeletal Muscle Wasting

(2016) Stephanie T. Isaac et al.   CURRENT DRUG TARGETS

Inhibition of ER stress and unfolding protein response pathways causes skeletal muscle wasting during cancer cachexia

(2016) Kyle R. Bohnert et al.   FASEB JOURNAL

Antioxidant supplementation accelerates cachexia development by promoting tumor growth in C26 tumor-bearing mice

(2016) Mohamad Assi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Deubiquitinating enzymes in skeletal muscle atrophy—An essential role for USP19

(2016) Simon S. Wing   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Calpain research for drug discovery: challenges and potential

(2016) Yasuko Ono et al.   NATURE REVIEWS DRUG DISCOVERY

Dantrolene improves in vitro structural changes induced by serum from Trypanosoma cruzi-infected mice

(2016) Lygia M. Malvestio et al.   PARASITOLOGY RESEARCH

Aerobic Exercise and Pharmacological Treatments Counteract Cachexia by Modulating Autophagy in Colon Cancer

(2016) Eva Pigna et al.   Scientific Reports

A multifactorial anti-cachectic approach for cancer cachexia in a rat model undergoing chemotherapy

(2015) Míriam Toledo et al.   Journal of Cachexia Sarcopenia and Muscle

Effect of the specific proteasome inhibitor bortezomib on cancer-related muscle wasting

(2015) Fabio Penna et al.   Journal of Cachexia Sarcopenia and Muscle

Differential regulation of the calpain–calpastatin complex by the L-domain of calpastatin

(2014) Roberta De Tullio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Pharmacological Strategies in Lung Cancer-Induced Cachexia: Effects on Muscle Proteolysis, Autophagy, Structure, and Weakness

(2014) Alba Chacon-Cabrera et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Autophagic-lysosomal pathway is the main proteolytic system modified in the skeletal muscle of esophageal cancer patients

(2013) Nicolas Tardif et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Autophagic Degradation Contributes to Muscle Wasting in Cancer Cachexia

(2013) Fabio Penna et al.   AMERICAN JOURNAL OF PATHOLOGY

Mitochondrial dysfunction and therapeutic approaches in respiratory and limb muscles of cancer cachectic mice

(2013) Clara Fermoselle et al.   EXPERIMENTAL PHYSIOLOGY

Cooperation between proteolytic systems in cardiomyocyte recycling

(2012) O. Yamaguchi et al.   CARDIOVASCULAR RESEARCH

CALPAIN activity is increased in skeletal muscle from gastric cancer patients with no or minimal weight loss

(2011) Ira J. Smith et al.   MUSCLE & NERVE

Oxidation enhances myofibrillar protein degradation via calpain and caspase-3

(2010) Ashley J. Smuder et al.   FREE RADICAL BIOLOGY AND MEDICINE

AAV-mediated expression of wild-type and ALS-linked mutant VAPB selectively triggers death of motoneurons through a Ca2+-dependent ER-associated pathway

(2010) Karine Langou et al.   JOURNAL OF NEUROCHEMISTRY

Human Immunodeficiency Virus-1 Tat Activates Calpain Proteases via the Ryanodine Receptor to Enhance Surface Dopamine Transporter Levels and Increase Transporter-Specific Uptake and Vmax

(2010) S. W. Perry et al.   JOURNAL OF NEUROSCIENCE

Deacetylase Inhibitors Modulate the Myostatin/Follistatin Axis without Improving Cachexia in Tumor-Bearing Mice

(2009) A. Bonetto et al.   CURRENT CANCER DRUG TARGETS

Up-regulation of calcium-dependent proteolysis in human myoblasts under acute oxidative stress

(2009) Elise Dargelos et al.   EXPERIMENTAL CELL RESEARCH

Muscle atrophy in experimental cancer cachexia: Is the IGF-1 signaling pathway involved?

(2009) Fabio Penna et al.   INTERNATIONAL JOURNAL OF CANCER

Role of the calpain–calpastatin system in the density-dependent growth arrest

(2008) Roberto Stifanese et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Involvement of exon 6-mediated calpastatin intracellular movements in the modulation of calpain activation

(2008) Roberta De Tullio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Muscle wasting in diabetic and in tumor-bearing rats: Role of oxidative stress

(2007) Raffaella Mastrocola et al.   FREE RADICAL BIOLOGY AND MEDICINE