Pharmacological Strategies in Lung Cancer-Induced Cachexia: Effects on Muscle Proteolysis, Autophagy, Structure, and Weakness

B-cell translocation gene 2 mediates crosstalk between PI3K/Akt1 and NFκB pathways which enhances transcription of MnSOD by accelerating IκBα degradation in normal and cancer cells

(2013) Santhoshkumar Sundaramoorthy et al.   Cell Communication and Signaling

Inhibition of Cisplatin-Induced Lipid Catabolism and Weight Loss by Ghrelin in Male Mice

(2013) Jose M. Garcia et al.   ENDOCRINOLOGY

Diaphragm and ventilatory dysfunction during cancer cachexia

(2013) Brandon M. Roberts et al.   FASEB JOURNAL

The metabolic modulator trimetazidine triggers autophagy and counteracts stress-induced atrophy in skeletal muscle myotubes

(2013) Elisabetta Ferraro et al.   FEBS Journal

Importance of functional and metabolic impairments in the characterization of the C-26 murine model of cancer cachexia

(2012) K. T. Murphy et al.   Disease Models & Mechanisms

Does oxidative stress modulate limb muscle atrophy in severe COPD patients?

(2012) Clara Fermoselle et al.   EUROPEAN RESPIRATORY JOURNAL

DHA Effect on Chemotherapy-Induced Body Weight Loss: An Exploratory Study in a Rodent Model of Mammary Tumors

(2012) Nawale Hajjaji et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Cigarette smoke-induced oxidative stress in skeletal muscles of mice

(2012) Esther Barreiro et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Proteasome inhibition improves diaphragm function in an animal model for COPD

(2011) Hieronymus van Hees et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Changes in Myostatin Signaling in Non-Weight-Losing Cancer Patients

(2011) Zaira Aversa et al.   ANNALS OF SURGICAL ONCOLOGY

Reducción de la masa muscular mediada por miostatina en un modelo experimental de enfisema pulmonar

(2011) Clara Fermoselle et al.   ARCHIVOS DE BRONCONEUMOLOGIA

The role of TRAIL in mediating autophagy in myositis skeletal muscle: A potential nonimmune mechanism of muscle damage

(2011) Heather M. Alger et al.   ARTHRITIS AND RHEUMATISM

Targeting Protein Synthesis in a Myc/mTOR-Driven Model of Anorexia-Cachexia Syndrome Delays Its Onset and Prolongs Survival

(2011) F. Robert et al.   CANCER RESEARCH

Anti-inflammatory therapies in cancer cachexia

(2011) Josep M. Argilés et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Inflammatory cells and apoptosis in respiratory and limb muscles of patients with COPD

(2011) Esther Barreiro et al.   JOURNAL OF APPLIED PHYSIOLOGY

Nutrition Modulation of Gastrointestinal Toxicity Related to Cancer Chemotherapy

(2011) Hongyu Xue et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Myostatin blockage using actRIIB antagonism in mice bearing the Lewis lung carcinoma results in the improvement of muscle wasting and physical performance

(2011) Sílvia Busquets et al.   Journal of Cachexia Sarcopenia and Muscle

Cigarette Smoke–induced Oxidative Stress

(2010) Esther Barreiro et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Resistance Training Prevents Deterioration in Quadriceps Muscle Function During Acute Exacerbations of Chronic Obstructive Pulmonary Disease

(2010) Thierry Troosters et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival

(2010) Xiaolan Zhou et al.   CELL

Effect of pulmonary rehabilitation on muscle remodelling in cachectic patients with COPD

(2010) I. Vogiatzis et al.   EUROPEAN RESPIRATORY JOURNAL

Reference values of respiratory and peripheral muscle function in rats

(2010) E. Barreiro et al.   JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION

Nutritional Recommendations for the Management of Sarcopenia

(2010) John E. Morley et al.   Journal of the American Medical Directors Association

Progressive skeletal muscle weakness in transgenic mice expressing CTG expansions is associated with the activation of the ubiquitin–proteasome pathway

(2010) Alban Vignaud et al.   NEUROMUSCULAR DISORDERS

Muscle Wasting and Impaired Myogenesis in Tumor Bearing Mice Are Prevented by ERK Inhibition

(2010) Fabio Penna et al.   PLoS One

Cachexia as a major underestimated and unmet medical need: facts and numbers

(2010) Stephan von Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting

(2009) J. M. McClung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Effect of proteasome inhibitors on endotoxin-induced diaphragm dysfunction

(2009) G. S. Supinski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Redox Balance and Carbonylated Proteins in Limb and Heart Muscles of Cachectic Rats

(2009) Judith Marin-Corral et al.   ANTIOXIDANTS & REDOX SIGNALING

Inhibition of the MAP kinase ERK protects from lipopolysaccharide-induced lung injury

(2009) Katrin Schuh et al.   BIOCHEMICAL PHARMACOLOGY

Atrophy and hypertrophy signalling in the diaphragm of patients with COPD

(2009) D. Testelmans et al.   EUROPEAN RESPIRATORY JOURNAL

Effect of Sulfasalazine on Renal Ischemia/Reperfusion Injury in Rats

(2009) Carlos Rodrigo Cámara-Lemarroy et al.   RENAL FAILURE

Proteasome inhibition improves diaphragm function in congestive heart failure rats

(2008) Hieronymus W. H. van Hees et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cachexia: A new definition

(2008) William J. Evans et al.   CLINICAL NUTRITION

EFFICACY OF SULPHASALAZINE ON LUNG HISTOPATHOLOGY IN A MURINE MODEL OF CHRONIC ASTHMA

(2008) Duygu Olmez et al.   EXPERIMENTAL LUNG RESEARCH

UCP3 overexpression neutralizes oxidative stress rather than nitrosative stress in mouse myotubes

(2008) Esther Barreiro et al.   FEBS LETTERS

Muscle wasting in diabetic and in tumor-bearing rats: Role of oxidative stress

(2007) Raffaella Mastrocola et al.   FREE RADICAL BIOLOGY AND MEDICINE