Central Administration of 5Z-7-Oxozeaenol Protects Experimental Autoimmune Encephalomyelitis Mice by Inhibiting Microglia Activation

Suppression of murine experimental autoimmune encephalomyelitis development by 1,25-dihydroxyvitamin D3 with autophagy modulation

(2015) Chao Zhen et al.   JOURNAL OF NEUROIMMUNOLOGY

Recombinant human PDCD5 (rhPDCD5) protein is protective in a mouse model of multiple sclerosis

(2015) Juan Xiao et al.   Journal of Neuroinflammation

Microglia-Mediated Inflammation and Neurodegenerative Disease

(2015) Ling Xu et al.   MOLECULAR NEUROBIOLOGY

18β-glycyrrhetinic acid suppresses experimental autoimmune encephalomyelitis through inhibition of microglia activation and promotion of remyelination

(2015) Jieru Zhou et al.   Scientific Reports

Pathogenesis of multiple sclerosis: insights from molecular and metabolic imaging

(2014) Olga Ciccarelli et al.   LANCET NEUROLOGY

The role of microglial activation in disease progression

(2014) Jorge Correale   Multiple Sclerosis Journal

Pertussis toxin modulates microglia and T cell profile to protect experimental autoimmune encephalomyelitis

(2014) Jun-xiang Yin et al.   NEUROPHARMACOLOGY

Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons

(2013) Shailender Singh et al.   ACTA NEUROPATHOLOGICA

Role of Microglia in CNS Autoimmunity

(2013) Tobias Goldmann et al.   Clinical & Developmental Immunology

A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

(2013) Tobias Goldmann et al.   NATURE NEUROSCIENCE

Cell type-specific function of TAK1 in innate immune signaling

(2013) Adebusola A. Ajibade et al.   TRENDS IN IMMUNOLOGY

Nuclear factor kappa B (NF-κB) in multiple sclerosis pathology

(2013) Conor Mc Guire et al.   TRENDS IN MOLECULAR MEDICINE

Mechanism and In Vitro Pharmacology of TAK1 Inhibition by (5Z)-7-Oxozeaenol

(2012) Jiaquan Wu et al.   ACS Chemical Biology

Natural triterpenes modulate immune-inflammatory markers of experimental autoimmune encephalomyelitis: therapeutic implications for multiple sclerosis

(2012) R Martín et al.   BRITISH JOURNAL OF PHARMACOLOGY

TAK1, more than just innate immunity

(2012) Liang Dai et al.   IUBMB LIFE

Mechanism for p38α-mediated Experimental Autoimmune Encephalomyelitis

(2012) Kana Namiki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transgenic inhibition of astroglial NF-κB protects from optic nerve damage and retinal ganglion cell loss in experimental optic neuritis

(2012) Roberta Brambilla et al.   Journal of Neuroinflammation

Constitutive activity of NF-kappa B in myeloid cells drives pathogenicity of monocytes and macrophages during autoimmune neuroinflammation

(2012) Gisa Ellrichmann et al.   Journal of Neuroinflammation

Progressive multiple sclerosis: pathology and pathogenesis

(2012) Hans Lassmann et al.   Nature Reviews Neurology

Targeting of TAK1 in inflammatory disorders and cancer

(2012) Hiroaki Sakurai   TRENDS IN PHARMACOLOGICAL SCIENCES

Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL/6 mice

(2011) Ewa Kozela et al.   BRITISH JOURNAL OF PHARMACOLOGY

Acute inhibition of TAK1 protects against neuronal death in cerebral ischemia

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In vivo RNAi-mediated silencing of TAK1 decreases inflammatory Th1 and Th17 cells through targeting of myeloid cells

(2010) G. Courties et al.   BLOOD

Role of Cytokines as Mediators and Regulators of Microglial Activity in Inflammatory Demyelination of the CNS

(2010) Tobias D. Merson et al.   NEUROMOLECULAR MEDICINE

Targeting protein kinases for the development of anti-inflammatory drugs

(2009) Philip Cohen   CURRENT OPINION IN CELL BIOLOGY

Cytokines and Myelination in the Central Nervous System

(2008) Thomas Schmitz et al.   TheScientificWorldJOURNAL