In vivo RNAi-mediated silencing of TAK1 decreases inflammatory Th1 and Th17 cells through targeting of myeloid cells

Macrophages as APC and the Dendritic Cell Myth

(2014) D. A. Hume   JOURNAL OF IMMUNOLOGY

Enterocyte-Derived TAK1 Signaling Prevents Epithelium Apoptosis and the Development of Ileitis and Colitis

(2014) R. Kajino-Sakamoto et al.   JOURNAL OF IMMUNOLOGY

A critical role of TAK1 in B-cell receptor–mediated nuclear factor κB activation

(2009) James Schuman et al.   BLOOD

Targeting protein kinases for the development of anti-inflammatory drugs

(2009) Philip Cohen   CURRENT OPINION IN CELL BIOLOGY

TAK1 is an essential regulator of BMP signalling in cartilage

(2009) Jae-Hyuck Shim et al.   EMBO JOURNAL

Adoptive transfer of IL-10-secreting CD4+CD49b+ regulatory T cells suppresses ongoing arthritis

(2009) Louis-Marie Charbonnier et al.   JOURNAL OF AUTOIMMUNITY

Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation

(2009) Myriam Aouadi et al.   NATURE

The promises and pitfalls of RNA-interference-based therapeutics

(2009) Daniela Castanotto et al.   NATURE

Interaction between TAK1–TAB1–TAB2 and RCAN1–calcineurin defines a signalling nodal control point

(2009) Qinghang Liu et al.   NATURE CELL BIOLOGY

Targeting innate immunity protein kinase signalling in inflammation

(2009) Matthias Gaestel et al.   NATURE REVIEWS DRUG DISCOVERY

Efficient suppression of murine arthritis by combined anticytokine small interfering RNA lipoplexes

(2008) Maroun Khoury et al.   ARTHRITIS AND RHEUMATISM

A potent and selective p38 inhibitor protects against bone damage in murine collagen-induced arthritis: a comparison with neutralization of mouse TNFα

(2008) K Mihara et al.   BRITISH JOURNAL OF PHARMACOLOGY

Evidence that cytokines play a role in rheumatoid arthritis

(2008) Fionula M. Brennan et al.   JOURNAL OF CLINICAL INVESTIGATION

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

(2008) Shahla Abdollahi-Roodsaz et al.   JOURNAL OF CLINICAL INVESTIGATION

TAK1 is required for the survival of hematopoietic cells and hepatocytes in mice

(2008) Minghui Tang et al.   JOURNAL OF EXPERIMENTAL MEDICINE