Anhuienoside C Ameliorates Collagen-Induced Arthritis through Inhibition of MAPK and NF-κB Signaling Pathways

Bioactive triterpenoids from the leaves of Eriobotrya japonica as the natural PDE4 inhibitors

(2017) Bing-Xin Tan et al.   NATURAL PRODUCT RESEARCH

Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression

(2016) E A Ross et al.   ANNALS OF THE RHEUMATIC DISEASES

Biological Evaluation and Docking Analysis of Daturaolone as Potential Cyclooxygenase Inhibitor

(2016) Abdur Rauf et al.   Evidence-based Complementary and Alternative Medicine

Majoon ushba, a polyherbal compound, suppresses pro-inflammatory mediators and RANKL expression via modulating NFкB and MAPKs signaling pathways in fibroblast-like synoviocytes from adjuvant-induced arthritic rats

(2016) Ramamoorthi Ganesan et al.   IMMUNOLOGIC RESEARCH

Glorisa superbaHydroalcoholic Extract from Tubers Attenuates Experimental Arthritis by Downregulating Inflammatory Mediators, and Phosphorylation of ERK/JNK/p-38

(2016) Rohit Kumar et al.   IMMUNOLOGICAL INVESTIGATIONS

The bispecific antibody aimed at the vicious circle of IL-1β and IL-17A, is beneficial for the collagen-induced rheumatoid arthritis of mice through NF-κB signaling pathway

(2016) Qiang Wu et al.   IMMUNOLOGY LETTERS

Chronic Calcium Channel Inhibitor Verapamil Antagonizes TNF-α-Mediated Inflammatory Reaction and Protects Against Inflammatory Arthritis in Mice

(2016) Wenhan Wang et al.   INFLAMMATION

Plantamajoside ameliorates lipopolysaccharide-induced acute lung injury via suppressing NF-κB and MAPK activation

(2016) Haichong Wu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Triptolide inhibits the migration and invasion of rheumatoid fibroblast-like synoviocytes by blocking the activation of the JNK MAPK pathway

(2016) Yanlong Yang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Macrophage heterogeneity in the context of rheumatoid arthritis

(2016) Irina A. Udalova et al.   Nature Reviews Rheumatology

Salidroside ameliorates arthritis-induced brain cognition deficits by regulating Rho/ROCK/NF-κB pathway

(2016) Lingpeng Zhu et al.   NEUROPHARMACOLOGY

Chitosan oligosaccharide suppresses synovial inflammation via AMPK activation: An in vitro and in vivo study

(2016) Wanlop Kunanusornchai et al.   PHARMACOLOGICAL RESEARCH

The prolactin receptor is expressed in rheumatoid arthritis and psoriatic arthritis synovial tissue and contributes to macrophage activation

(2016) Man Wai Tang et al.   RHEUMATOLOGY

Critical Role of Glucose Metabolism in Rheumatoid Arthritis Fibroblast-like Synoviocytes

(2016) Ricard Garcia-Carbonell et al.   Arthritis & Rheumatology

A novel NF-κB/YY1/microRNA-10a regulatory circuit in fibroblast-like synoviocytes regulates inflammation in rheumatoid arthritis

(2016) Nan Mu et al.   Scientific Reports

Expression of chemokines CXCL4 and CXCL7 by synovial macrophages defines an early stage of rheumatoid arthritis

(2015) L Yeo et al.   ANNALS OF THE RHEUMATIC DISEASES

A Truncated Variant of ASCC1, a Novel Inhibitor of NF- B, Is Associated with Disease Severity in Patients with Rheumatoid Arthritis

(2015) S. Torices et al.   JOURNAL OF IMMUNOLOGY

Crude triterpenoid saponins from Anemone flaccida (Di Wu) exert anti-arthritic effects on type II collagen-induced arthritis in rats

(2015) Qing Liu et al.   Chinese Medicine

Updated Research and Applications of Small Molecule Inhibitors of Keap1-Nrf2 Protein-Protein Interaction: a Review

(2014) Chunlin Zhuang et al.   CURRENT MEDICINAL CHEMISTRY

Esculentic acid, a novel and selective COX-2 inhibitor with anti-inflammatory effect in vivo and in vitro

(2014) Xiaofeng Niu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Triterpenoid saponins from the rhizomes ofAnemone flaccidaand their inhibitory activities on LPS-induced NO production in macrophage RAW264.7 cells

(2014) Xiao-Jun Huang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Tumor Necrosis Factor-  Inhibitor Treatment and the Risk of Incident Cardiovascular Events in Patients with Early Rheumatoid Arthritis: A Nested Case-control Study

(2014) R. J. Desai et al.   JOURNAL OF RHEUMATOLOGY

Interleukin 6 and Rheumatoid Arthritis

(2014) Yuji Yoshida et al.   Biomed Research International

The Antitumor Effects of Triterpenoid Saponins from theAnemone flaccidaand the Underlying Mechanism

(2013) Lin-Tao Han et al.   Evidence-based Complementary and Alternative Medicine

(E)-3-(3,4-Dimethoxyphenyl)-1-(5-hydroxy-2,2-dimethyl-2H-chromen-6-yl)prop-2-en-1-one ameliorates the collagen-arthritis via blocking ERK/JNK and NF-κB signaling pathway

(2013) Xiuxia Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Targeting interleukin-6 in inflammatory autoimmune diseases and cancers

(2013) Xin Yao et al.   PHARMACOLOGY & THERAPEUTICS

Therapeutic effects of a novel tylophorine analog, NK-007, on collagen-induced arthritis through suppressing tumor necrosis factor α production and Th17 cell differentiation

(2012) Ti Wen et al.   ARTHRITIS AND RHEUMATISM

Therapeutic role of a vaccine targeting RANKL and TNF-α on collagen-induced arthritis

(2012) Huihui Yuan et al.   BIOMATERIALS

Suppression of PU.1-linked TLR4 expression by cilostazol with decrease of cytokine production in macrophages from patients with rheumatoid arthritis

(2012) SY Park et al.   BRITISH JOURNAL OF PHARMACOLOGY

Magnolol inhibits lipopolysaccharide-induced inflammatory response by interfering with TLR4 mediated NF-κB and MAPKs signaling pathways

(2012) Yunhe Fu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Mapping pathogenesis of arthritis through small animal models

(2012) T. L. Vincent et al.   RHEUMATOLOGY

Evaluation of therapeutic targets in animal models of arthritis: How does it relate to rheumatoid arthritis?

(2010) Lisette Bevaart et al.   ARTHRITIS AND RHEUMATISM

Interleukin-6: From identification of the cytokine to development of targeted treatments

(2010) Eric Assier et al.   JOINT BONE SPINE

Triterpene Saponins fromClematis chinensisand Their Potential Anti-inflammatory Activity

(2010) Qiang Fu et al.   JOURNAL OF NATURAL PRODUCTS

Rheumatoid arthritis

(2009) Lars Klareskog et al.   LANCET

The role of Toll-like receptors in rheumatoid arthritis

(2009) Qi-Quan Huang et al.   Current Rheumatology Reports

Antitumor triterpene saponins from Anemone flaccida

(2008) Lan Tian Zhang et al.   CHINESE CHEMICAL LETTERS