Deletion of TRPC6 Attenuates NMDA Receptor-Mediated Ca2+ Entry and Ca2+-Induced Neurotoxicity Following Cerebral Ischemia and Oxygen-Glucose Deprivation

Stroke research at the crossroads - where are we heading?

(2016) S Roth et al.   SWISS MEDICAL WEEKLY

The role of TRPC6 in oxidative stress-induced podocyte ischemic injury

(2015) Bo Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Novel Mechanism of Spine Damages in Stroke via DAPK1 and Tau

(2015) Lei Pei et al.   CEREBRAL CORTEX

Triclosan induces Fas receptor-dependent apoptosis in mouse neocortical neurons in vitro

(2015) K.A. Szychowski et al.   NEUROSCIENCE

TRPM7 inhibitor carvacrol protects brain from neonatal hypoxic-ischemic injury

(2015) Wenliang Chen et al.   Molecular Brain

Spatially selective photoconductive stimulation of live neurons

(2014) Jacob Campbell et al.   Frontiers in Cellular Neuroscience

High glucose-induced apoptosis in cultured podocytes involves TRPC6-dependent calcium entry via the RhoA/ROCK pathway

(2013) He Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Increased expression of the transient receptor potential cation channel 6 gene in patients with primary open-angle glaucoma

(2013) Shida Chen et al.   CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Neuroprotective Effect of Resveratrol on Ischemia/Reperfusion Injury in Rats Through TRPC6/CREB Pathways

(2013) Yun Lin et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Pdx-1 Activates Islet  - and  -Cell Proliferation via a Mechanism Regulated by Transient Receptor Potential Cation Channels 3 and 6 and Extracellular Signal-Regulated Kinases 1 and 2

(2013) H. L. Hayes et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of the ubiquitin–proteasome system in brain ischemia: Friend or foe?

(2013) Margarida V. Caldeira et al.   PROGRESS IN NEUROBIOLOGY

Current understanding of TRPM7 pharmacology and drug development for stroke

(2012) Christine You Jin Bae et al.   ACTA PHARMACOLOGICA SINICA

Hyperforin Attenuates Brain Damage Induced by Transient Middle Cerebral Artery Occlusion (MCAO) in Rats via Inhibition of TRPC6 Channels Degradation

(2012) Yun Lin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation

(2012) Mohammad Tauseef et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Propidium iodide staining: A new application in fluorescence microscopy for analysis of cytoarchitecture in adult and developing rodent brain

(2012) Marcus Hezel et al.   MICRON

Activation of TRPC6 channels is essential for lung ischaemia–reperfusion induced oedema in mice

(2012) Norbert Weissmann et al.   Nature Communications

Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart

(2012) Jian Xie et al.   Nature Communications

TRPM7 in cerebral ischemia and potential target for drug development in stroke

(2011) Christine You-jin Bae et al.   ACTA PHARMACOLOGICA SINICA

Notch Activation Enhances the Microglia-Mediated Inflammatory Response Associated With Focal Cerebral Ischemia

(2011) Zelan Wei et al.   STROKE

DAPK1 Interaction with NMDA Receptor NR2B Subunits Mediates Brain Damage in Stroke

(2010) Weihong Tu et al.   CELL

Inhibition of transient receptor potential canonical channels impairs cytokinesis in human malignant gliomas

(2010) V. C. Bomben et al.   CELL PROLIFERATION

Inhibition of TRPC6 degradation suppresses ischemic brain damage in rats

(2010) Wanlu Du et al.   JOURNAL OF CLINICAL INVESTIGATION

Essential Role of TRPC6 Channels in G2/M Phase Transition and Development of Human Glioma

(2010) Xia Ding et al.   JNCI-Journal of the National Cancer Institute

Podocyte-Specific Overexpression of Wild Type or Mutant Trpc6 in Mice Is Sufficient to Cause Glomerular Disease

(2010) Paola Krall et al.   PLoS One

Receptor Channel TRPC6 Is a Key Mediator of Notch-Driven Glioblastoma Growth and Invasiveness

(2009) S. Chigurupati et al.   CANCER RESEARCH

Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia

(2009) Hong-Shuo Sun et al.   NATURE NEUROSCIENCE

Calcium Imaging of Cortical Neurons using Fura-2 AM

(2009) Odmara L Barreto-Chang et al.   Jove-Journal of Visualized Experiments

Diacylglycerol analogues activate second messenger-operated calcium channels exhibiting TRPC-like properties in cortical neurons

(2008) Peng Tu et al.   JOURNAL OF NEUROCHEMISTRY

Critical role of TRPC6 channels in the formation of excitatory synapses

(2008) Jian Zhou et al.   NATURE NEUROSCIENCE

Roles of TRP channels in the development of cardiac hypertrophy

(2008) Motohiro Nishida et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY