Pdx-1 Activates Islet  - and  -Cell Proliferation via a Mechanism Regulated by Transient Receptor Potential Cation Channels 3 and 6 and Extracellular Signal-Regulated Kinases 1 and 2

Transient overexpression of cyclin D2/CDK4/GLP1 genes induces proliferation and differentiation of adult pancreatic progenitors and mediates islet regeneration

(2012) Shuyuan Chen et al.   CELL CYCLE

A VGF-Derived Peptide Attenuates Development of Type 2 Diabetes via Enhancement of Islet β-Cell Survival and Function

(2012) Samuel B. Stephens et al.   Cell Metabolism

TRPC Channels and Their Splice Variants are Essential for Promoting Human Ovarian Cancer Cell Proliferation and Tumorigenesis

(2012) Bo Zeng et al.   CURRENT CANCER DRUG TARGETS

Research Resource: The Pdx1 Cistrome of Pancreatic Islets

(2012) Cynthia Khoo et al.   MOLECULAR ENDOCRINOLOGY

Overexpression of Hepatocyte Nuclear Factor-4α Initiates Cell Cycle Entry, but Is not Sufficient to Promote β-Cell Expansion in Human Islets

(2012) Sebastian Rieck et al.   MOLECULAR ENDOCRINOLOGY

The role of thermosensitive TRP (transient receptor potential) channels in insulin secretion [Review]

(2011) Kunitoshi Uchida et al.   ENDOCRINE JOURNAL

Context-specific  -to- -cell reprogramming by forced Pdx1 expression

(2011) Y.-P. Yang et al.   GENES & DEVELOPMENT

Transgenic Overexpression of the Transcription Factor Nkx6.1 in β-Cells of Mice Does Not Increase β-Cell Proliferation, β-Cell Mass, or Improve Glucose Clearance

(2011) Ashleigh E. Schaffer et al.   MOLECULAR ENDOCRINOLOGY

TRPM2 modulates insulin secretion in pancreatic β-cells

(2011) Kunitoshi Uchida et al.   Islets

Stem cell approaches for diabetes: towards beta cell replacement

(2011) Gordon C Weir et al.   Genome Medicine

PDX-1

(2010) Shi-He Liu et al.   CANCER

Induction of Human β-Cell Proliferation and Engraftment Using a Single G1/S Regulatory Molecule, cdk6

(2010) Nathalie M. Fiaschi-Taesch et al.   DIABETES

TRPC3 cation channel plays an important role in proliferation and differentiation of skeletal muscle myoblasts

(2010) Jin Seok Woo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Calcineurin Signaling Regulates Human Islet β-Cell Survival

(2010) Scott A. Soleimanpour et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ca 2+ influx and protein scaffolding via TRPC3 sustain PKCβ and ERK activation in B cells

(2010) Takuro Numaga et al.   JOURNAL OF CELL SCIENCE

Essential Role of TRPC6 Channels in G2/M Phase Transition and Development of Human Glioma

(2010) Xia Ding et al.   JNCI-Journal of the National Cancer Institute

Contamination with E1A-Positive Wild-Type Adenovirus Accounts for Species-Specific Stimulation of Islet Cell Proliferation by CCK: A Cautionary Note

(2010) Jeremy A. Lavine et al.   MOLECULAR ENDOCRINOLOGY

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

Pancreatic β-Cell Neogenesis by Direct Conversion from Mature α-Cells

(2010) Cheng-Ho Chung et al.   STEM CELLS

Autophagy Regulates Pancreatic Beta Cell Death in Response to Pdx1 Deficiency and Nutrient Deprivation

(2009) Kei Fujimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress

(2009) Mira M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Calcium-Permeable TRPV2 Channel by Insulin in Pancreatic  -Cells

(2008) E. Hisanaga et al.   DIABETES

Stimulation of Human and Rat Islet  -Cell Proliferation with Retention of Function by the Homeodomain Transcription Factor Nkx6.1

(2008) J. C. Schisler et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes

(2008) Deborah M. Muoio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PDX-1 Expression Is Associated with Islet Proliferation In Vitro and In Vivo

(2007) Mark A. Feanny et al.   JOURNAL OF SURGICAL RESEARCH