Modulating protein amyloid aggregation with nanomaterials

Investigating the inhibitory effects of zinc ions on amyloid fibril formation of hen egg-white lysozyme

(2017) Baoliang Ma et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Vitamin B12 offers neuronal cell protection by inhibiting Aβ-42 amyloid fibrillation

(2017) Parvez Alam et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Binding and Inhibitory Effect of the Dyes Amaranth and Tartrazine on Amyloid Fibrillation in Lysozyme

(2017) Anirban Basu et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Probing the Aggregation Mechanism of Gold Nanoparticles Triggered by a Globular Protein

(2017) Sunanda Neupane et al.   Journal of Physical Chemistry C

Molecular interaction between type 2 diabetes and Alzheimer’s disease through cross-seeding of protein misfolding

(2017) I Moreno-Gonzalez et al.   MOLECULAR PSYCHIATRY

Amyloid fibril systems reduce, stabilize and deliver bioavailable nanosized iron

(2017) Yi Shen et al.   Nature Nanotechnology

Heparin-induced amyloid fibrillation of β2 -microglobulin explained by solubility and a supersaturation-dependent conformational phase diagram

(2017) Masatomo So et al.   PROTEIN SCIENCE

The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril

(2017) Einav Tayeb-Fligelman et al.   SCIENCE

Design of a Molecular Hybrid of Dual Peptide Inhibitors Coupled on AuNPs for Enhanced Inhibition of Amyloid β-Protein Aggregation and Cytotoxicity

(2017) Neng Xiong et al.   Small

Protein-Nanoparticle Interaction-Induced Changes in Protein Structure and Aggregation

(2016) Yuna Kim et al.   Chemistry-An Asian Journal

Considerations of Environmentally Relevant Test Conditions for Improved Evaluation of Ecological Hazards of Engineered Nanomaterials

(2016) Patricia A. Holden et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

A Voxel-Based Morphometry Study Reveals Local Brain Structural Alterations Associated with Ambient Fine Particles in Older Women

(2016) Ramon Casanova et al.   Frontiers in Human Neuroscience

'Safe handling of nanotechnology' ten years on

(2016) Andrew D. Maynard et al.   Nature Nanotechnology

Amyloid–carbon hybrid membranes for universal water purification

(2016) Sreenath Bolisetty et al.   Nature Nanotechnology

Neurodegenerative and neurological disorders by small inhaled particles

(2016) Harm J. Heusinkveld et al.   NEUROTOXICOLOGY

The inhibitory mechanism of a fullerene derivative against amyloid-β peptide aggregation: an atomistic simulation study

(2016) Yunxiang Sun et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Brushed polyethylene glycol and phosphorylcholine for grafting nanoparticles against protein binding

(2016) Bo Wang et al.   Polymer Chemistry

Magnetite pollution nanoparticles in the human brain

(2016) Barbara A. Maher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of hIAPP Amyloid Aggregation and Pancreatic β-Cell Toxicity by OH-Terminated PAMAM Dendrimer

(2016) Esteban N. Gurzov et al.   Small

Pathophysiologic mechanisms of biomedical nanomaterials

(2016) Liming Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Current understanding of interactions between nanoparticles and the immune system

(2016) Marina A. Dobrovolskaia et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

How Do the Size, Charge and Shape of Nanoparticles Affect Amyloid β Aggregation on Brain Lipid Bilayer?

(2016) Yuna Kim et al.   Scientific Reports

Stabilizing Off-pathway Oligomers by Polyphenol Nanoassemblies for IAPP Aggregation Inhibition

(2016) Praveen Nedumpully-Govindan et al.   Scientific Reports

Nanomaterial Categorization for Assessing Risk Potential To Facilitate Regulatory Decision-Making

(2015) Hilary Godwin et al.   ACS Nano

Neuropathologically mixed Alzheimer’s and Lewy body disease: burden of pathological protein aggregates differs between clinical phenotypes

(2015) Lauren Walker et al.   ACTA NEUROPATHOLOGICA

Towards understanding of nanoparticle–protein corona

(2015) Cuicui Ge et al.   ARCHIVES OF TOXICOLOGY

Ferric Ions Inhibit the Amyloid Fibrillation of β-Lactoglobulin at High Temperature

(2015) Rita Guzzi et al.   BIOMACROMOLECULES

In vivo delivery, pharmacokinetics, biodistribution and toxicity of iron oxide nanoparticles

(2015) Hamed Arami et al.   CHEMICAL SOCIETY REVIEWS

Modeling Nanomaterial Environmental Fate in Aquatic Systems

(2015) Amy L. Dale et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Inhibition of amyloid fibrillation and cytotoxicity of lysozyme fibrillation products by polyphenols

(2015) Sajad Shariatizi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Exploring the diameter and surface dependent conformational changes in carbon nanotube-protein corona and the related cytotoxicity

(2015) Xingchen Zhao et al.   JOURNAL OF HAZARDOUS MATERIALS

Self-Assembly of Molecule-like Nanoparticle Clusters Directed by DNA Nanocages

(2015) Yulin Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High Resolution Structural Characterization of Aβ42 Amyloid Fibrils by Magic Angle Spinning NMR

(2015) Michael T. Colvin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Destruction of amyloid fibrils by graphene through penetration and extraction of peptides

(2015) Zaixing Yang et al.   Nanoscale

Regulation and aggregation of intrinsically disordered peptides

(2015) Zachary A. Levine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineered nanoparticles in soils and waters

(2015) Gabriele E. Schaumann et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Contrasting effects of nanoparticle–protein attraction on amyloid aggregation

(2015) Slaven Radic et al.   RSC Advances

Inhibition of IAPP aggregation by insulin depends on the insulin oligomeric state regulated by zinc ion concentration

(2015) Praveen Nedumpully-Govindan et al.   Scientific Reports

Solid-state NMR sequential assignment of Osaka-mutant amyloid-beta (Aβ1−40 E22Δ) fibrils

(2014) Matthias Huber et al.   Biomolecular NMR Assignments

Cysteine inhibits amyloid fibrillation of lysozyme and directs the formation of small worm-like aggregates through non-covalent interactions

(2014) Eisuke Takai et al.   BIOTECHNOLOGY PROGRESS

Inhibition of Amyloid Fibril Growth and Dissolution of Amyloid Fibrils by Curcumin-Gold Nanoparticles

(2014) Sharbari Palmal et al.   CHEMISTRY-A EUROPEAN JOURNAL

What Macromolecular Crowding Can Do to a Protein

(2014) Irina Kuznetsova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Small Liposomes Accelerate the Fibrillation of Amyloid β (1–40)

(2014) Mayu S. Terakawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction of the Molecular Chaperone DNAJB6 with Growing Amyloid-beta 42 (Aβ42) Aggregates Leads to Sub-stoichiometric Inhibition of Amyloid Formation

(2014) Cecilia Månsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interactions of a Water-Soluble Fullerene Derivative with Amyloid-β Protofibrils: Dynamics, Binding Mechanism, and the Resulting Salt-Bridge Disruption

(2014) Xiaoying Zhou et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Surface Effects on Aggregation Kinetics of Amyloidogenic Peptides

(2014) Robert Vácha et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The molecular mechanism of fullerene-inhibited aggregation of Alzheimer's β-amyloid peptide fragment

(2014) Luogang Xie et al.   Nanoscale

Synthesis and patterning of tunable multiscale materials with engineered cells

(2014) Allen Y. Chen et al.   NATURE MATERIALS

Amyloid-β oligomers as a template for secondary amyloidosis in Alzheimer's disease

(2014) Marcos J. Guerrero-Muñoz et al.   NEUROBIOLOGY OF DISEASE

'Bio-nano interactions: new tools, insights and impacts': summary of the Royal Society discussion meeting

(2014) I. Lynch et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Impact of sequence on the molecular assembly of short amyloid peptides

(2014) Victoria A. Wagoner et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Fluorinated beta-sheet breaker peptides

(2014) Joana A. Loureiro et al.   Journal of Materials Chemistry B

Nanoparticle–protein corona complexes govern the biological fates and functions of nanoparticles

(2014) Cindy Gunawan et al.   Journal of Materials Chemistry B

Amylin deposition in the brain: A second amyloid in Alzheimer disease?

(2013) Kaleena Jackson et al.   ANNALS OF NEUROLOGY

Curli biogenesis: Order out of disorder

(2013) Margery L. Evans et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Testing synthetic amyloid-β aggregation inhibitor using single molecule atomic force spectroscopy

(2013) Francis T. Hane et al.   BIOSENSORS & BIOELECTRONICS

The Protein Corona Mediates the Impact of Nanomaterials and Slows Amyloid Beta Fibrillation

(2013) Morteza Mahmoudi et al.   CHEMBIOCHEM

Modulation of Curli Assembly and Pellicle Biofilm Formation by Chemical and Protein Chaperones

(2013) Emma K. Andersson et al.   CHEMISTRY & BIOLOGY

Biofilm Inhibitors that Target Amyloid Proteins

(2013) Diego Romero et al.   CHEMISTRY & BIOLOGY

Misfolding and Amyloid Aggregation of Apomyoglobin

(2013) Clara Iannuzzi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Conformational Ensemble and Polymorphism of the All-Atom Alzheimer’s Aβ37–42 Amyloid Peptide Oligomers

(2013) Phuong H. Nguyen et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Aβ(16–22) Peptides Can Assemble into Ordered β-Barrels and Bilayer β-Sheets, while Substitution of Phenylalanine 19 by Tryptophan Increases the Population of Disordered Aggregates

(2013) Luogang Xie et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Protein fibrillation and nanoparticle interactions: opportunities and challenges

(2013) Morteza Mahmoudi et al.   Nanoscale

Neurotoxicity of Amyloid  -Protein: Synaptic and Network Dysfunction

(2013) L. Mucke et al.   Cold Spring Harbor Perspectives in Medicine

Interaction of nanoparticles with proteins: relation to bio-reactivity of the nanoparticle

(2013) Shruti R Saptarshi et al.   JOURNAL OF NANOBIOTECHNOLOGY

Molecular Interaction of Proteins and Peptides with Nanoparticles

(2012) Anton A. Shemetov et al.   ACS Nano

Design and Synthesis of Fluorescent Pilicides and Curlicides: Bioactive Tools to Study Bacterial Virulence Mechanisms

(2012) Erik Chorell- et al.   CHEMISTRY-A EUROPEAN JOURNAL

Inhibition of Amyloid Formation

(2012) Torleif Härd et al.   JOURNAL OF MOLECULAR BIOLOGY

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Inhibition of Amyloid Peptide Fibrillation by Inorganic Nanoparticles: Functional Similarities with Proteins

(2011) Seong Il Yoo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protein−Nanoparticle Interactions: Opportunities and Challenges

(2011) Morteza Mahmoudi et al.   CHEMICAL REVIEWS

Physical−Chemical Aspects of Protein Corona: Relevance toin Vitroandin VivoBiological Impacts of Nanoparticles

(2011) Marco P. Monopoli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Effect of Nanoparticles on Amyloid Aggregation Depends on the Protein Stability and Intrinsic Aggregation Rate

(2011) C. Cabaleiro-Lago et al.   LANGMUIR

Nanoparticles: a boon to drug delivery, therapeutics, diagnostics and imaging

(2011) Suphiya Parveen et al.   Nanomedicine-Nanotechnology Biology and Medicine

Diversity, biogenesis and function of microbial amyloids

(2011) Luz P. Blanco et al.   TRENDS IN MICROBIOLOGY

Time Evolution of the Nanoparticle Protein Corona

(2010) Eudald Casals et al.   ACS Nano

Analytical strategies for detecting nanoparticle–protein interactions

(2010) Liwen Li et al.   ANALYST

Molecular mechanism of Thioflavin-T binding to amyloid fibrils

(2010) Matthew Biancalana et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Suppression of IAPP fibrillation at anionic lipid membranes via IAPP-derived amyloid inhibitors and insulin

(2010) Daniel Sellin et al.   BIOPHYSICAL CHEMISTRY

Synergistic Interactions between A , Tau, and  -Synuclein: Acceleration of Neuropathology and Cognitive Decline

(2010) L. K. Clinton et al.   JOURNAL OF NEUROSCIENCE

Interactions in the native state of monellin, which play a protective role against aggregation

(2010) Olga Szczepankiewicz et al.   Molecular BioSystems

Nanoparticle-Induced Folding and Fibril Formation of Coiled-Coil-Based Model Peptides

(2010) Sara C. Wagner et al.   Small

Interaction of Gold Nanoparticles with Common Human Blood Proteins

(2009) Silvia H. De Paoli Lacerda et al.   ACS Nano

Inhibition of beta 1–40 amyloid fibrillation with N-acetyl-l-cysteine capped quantum dots

(2009) Lehui Xiao et al.   BIOMATERIALS

Human Serum Albumin Inhibits Aβ Fibrillization through a “Monomer-Competitor” Mechanism

(2009) Julijana Milojevic et al.   BIOPHYSICAL JOURNAL

Induced β -Barrel Formation of the Alzheimer's A β 25–35 Oligomers on Carbon Nanotube Surfaces: Implication for Amyloid Fibril Inhibition

(2009) Zhaoming Fu et al.   BIOPHYSICAL JOURNAL

Inhibition of IAPP and IAPP(20−29)Fibrillation by Polymeric Nanoparticles

(2009) C. Cabaleiro-Lago et al.   LANGMUIR

Gold Nanoparticles Can Induce the Formation of Protein-based Aggregates at Physiological pH

(2009) Dongmao Zhang et al.   NANO LETTERS

Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation

(2009) Lynette Cegelski et al.   Nature Chemical Biology

What does the cell see?

(2009) Iseult Lynch et al.   Nature Nanotechnology

A Condensation-Ordering Mechanism in Nanoparticle-Catalyzed Peptide Aggregation

(2009) Stefan Auer et al.   PLoS Computational Biology

Intrinsically Disordered Proteins in Human Diseases: Introducing the D2 Concept

(2008) Vladimir N. Uversky et al.   Annual Review of Biophysics

The unfoldomics decade: an update on intrinsically disordered proteins

(2008) A Keith Dunker et al.   BMC GENOMICS

Mixed Brain Pathologies in Dementia: The BrainNet Europe Consortium Experience

(2008) Gabor G. Kovacs et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Inhibition of Amyloid β Protein Fibrillation by Polymeric Nanoparticles

(2008) Celia Cabaleiro-Lago et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein-nanoparticle interactions

(2008) Iseult Lynch et al.   Nano Today

Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type 2 diabetes

(2008) Judith Miklossy et al.   NEUROBIOLOGY OF AGING

Molecular structural basis for polymorphism in Alzheimer's  -amyloid fibrils

(2008) A. K. Paravastu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA