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Title
Soluble forms of tau are toxic in Alzheimer’s disease
Authors
Keywords
-
Journal
Translational Neuroscience
Volume 3, Issue 3, Pages -
Publisher
Walter de Gruyter GmbH
Online
2012-08-27
DOI
10.2478/s13380-012-0032-y
References
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- (2017) Kurt R. Brunden et al. JOURNAL OF ALZHEIMERS DISEASE
- Cytosolic Abnormally Hyperphosphorylated Tau But Not Paired Helical Filaments Sequester Normal MAPs and Inhibit Microtubule Assembly
- (2017) Khalid Iqbal et al. JOURNAL OF ALZHEIMERS DISEASE
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- (2017) Alexis Bretteville et al. JOURNAL OF ALZHEIMERS DISEASE
- A NH2 Tau Fragment Targets Neuronal Mitochondria at AD Synapses: Possible Implications for Neurodegeneration
- (2017) Giuseppina Amadoro et al. JOURNAL OF ALZHEIMERS DISEASE
- The Alzheimer's Disease Mitochondrial Cascade Hypothesis
- (2017) Russell H. Swerdlow et al. JOURNAL OF ALZHEIMERS DISEASE
- Amyloid- Peptide Oligomers Disrupt Axonal Transport through an NMDA Receptor-Dependent Mechanism That Is Mediated by Glycogen Synthase Kinase 3 in Primary Cultured Hippocampal Neurons
- (2013) H. Decker et al. JOURNAL OF NEUROSCIENCE
- Alzheimer’s disease: Pathogenesis and prevention
- (2012) Heiko Braak et al. Alzheimers & Dementia
- Alzheimer Mechanisms and Therapeutic Strategies
- (2012) Yadong Huang et al. CELL
- Protein–RNA interactions: new genomic technologies and perspectives
- (2012) Julian König et al. NATURE REVIEWS GENETICS
- Propagation of Tau Pathology in a Model of Early Alzheimer's Disease
- (2012) Alix de Calignon et al. NEURON
- Homeostatic responses by surviving cortical pyramidal cells in neurodegenerative tauopathy
- (2011) Johanna L. Crimins et al. ACTA NEUROPATHOLOGICA
- Tau Accumulation Causes Mitochondrial Distribution Deficits in Neurons in a Mouse Model of Tauopathy and in Human Alzheimer's Disease Brain
- (2011) Katherine J. Kopeikina et al. AMERICAN JOURNAL OF PATHOLOGY
- Amyloid-Dependent and Amyloid-Independent Stages of Alzheimer Disease
- (2011) Bradley T. Hyman ARCHIVES OF NEUROLOGY
- Tau-targeted treatment strategies in Alzheimer's disease
- (2011) Jürgen Götz et al. BRITISH JOURNAL OF PHARMACOLOGY
- Novel diffusion barrier for axonal retention of Tau in neurons and its failure in neurodegeneration
- (2011) Xiaoyu Li et al. EMBO JOURNAL
- A critical role for the PAR-1/MARK-tau axis in mediating the toxic effects of Aβ on synapses and dendritic spines
- (2011) Wendou Yu et al. HUMAN MOLECULAR GENETICS
- Brief update on different roles of tau in neurodegeneration
- (2011) Arne Ittner et al. IUBMB LIFE
- Are Tangles as Toxic as They Look?
- (2011) Tara L. Spires-Jones et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Reversibility of Tau-Related Cognitive Defects in a Regulatable FTD Mouse Model
- (2011) Astrid Sydow et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Soluble tau Species, Not Neurofibrillary Aggregates, Disrupt Neural System Integration in a tau Transgenic Model
- (2011) Leora M. Fox et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Early Improved and Late Defective Cognition Is Reflected by Dendritic Spines in Tau.P301L Mice
- (2011) A. Kremer et al. JOURNAL OF NEUROSCIENCE
- Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant
- (2011) A. Sydow et al. JOURNAL OF NEUROSCIENCE
- Amyloid- /Fyn-Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease
- (2011) E. D. Roberson et al. JOURNAL OF NEUROSCIENCE
- Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice
- (2011) Cristian A Lasagna-Reeves et al. Molecular Neurodegeneration
- Resolving controversies on the path to Alzheimer's therapeutics
- (2011) Dennis J Selkoe NATURE MEDICINE
- Linking Amyloid-ß and Tau: Amyloid-ß Induced Synaptic Dysfunction via Local Wreckage of the Neuronal Cytoskeleton
- (2011) Hans Zempel et al. Neurodegenerative Diseases
- The Many Faces of Tau
- (2011) Meaghan Morris et al. NEURON
- Tau-Targeted Immunization Impedes Progression of Neurofibrillary Histopathology in Aged P301L Tau Transgenic Mice
- (2011) Mian Bi et al. PLoS One
- Nanoparticles enhance brain delivery of blood-brain barrier-impermeable probes for in vivo optical and magnetic resonance imaging
- (2011) R. M. Koffie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Early calcium dysregulation in Alzheimer’s disease: setting the stage for synaptic dysfunction
- (2011) Shreaya Chakroborty et al. Science China-Life Sciences
- Preparation and Characterization of Neurotoxic Tau Oligomers
- (2010) Cristian A. Lasagna-Reeves et al. BIOCHEMISTRY
- Methylene Blue Reduces Aβ Levels and Rescues Early Cognitive Deficit by Increasing Proteasome Activity
- (2010) David X. Medina et al. BRAIN PATHOLOGY
- Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases
- (2010) P. Hemachandra Reddy et al. BRAIN RESEARCH REVIEWS
- Changes in dendritic complexity and spine morphology in transgenic mice expressing human wild-type tau
- (2010) Dara L. Dickstein et al. Brain Structure & Function
- Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models
- (2010) Lars M. Ittner et al. CELL
- Aggregation of Detergent-insoluble Tau Is Involved in Neuronal Loss but Not in Synaptic Loss
- (2010) Tetsuya Kimura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines
- (2010) H. Zempel et al. JOURNAL OF NEUROSCIENCE
- Immunotherapy Targeting Pathological Tau Prevents Cognitive Decline in a New Tangle Mouse Model
- (2010) A. Boutajangout et al. JOURNAL OF NEUROSCIENCE
- Convergence of Amyloid-β and Tau Pathologies on Mitochondria In Vivo
- (2010) Anne Eckert et al. MOLECULAR NEUROBIOLOGY
- Caspase activation precedes and leads to tangles
- (2010) Alix de Calignon et al. NATURE
- Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease
- (2010) Marcello D'Amelio et al. NATURE NEUROSCIENCE
- Mitochondrial fusion and fission in cell life and death
- (2010) Benedikt Westermann NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease
- (2010) Lars M. Ittner et al. NATURE REVIEWS NEUROSCIENCE
- Calcium Signalling and Alzheimer’s Disease
- (2010) Michael J. Berridge NEUROCHEMICAL RESEARCH
- Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration
- (2010) Brian R. Hoover et al. NEURON
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Multiple Events Lead to Dendritic Spine Loss in Triple Transgenic Alzheimer's Disease Mice
- (2010) Tobias Bittner et al. PLoS One
- Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model
- (2010) H. Du et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tau Reduction Prevents Aβ-Induced Defects in Axonal Transport: Fig. 1
- (2010) Keith A. Vossel et al. SCIENCE
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- (2009) Gary E. Gibson et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
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- (2009) Illana Gozes et al. Current Alzheimer Research
- Tau-directed drug discovery for Alzheimer's disease and related tauopathies: A focus on tau assembly inhibitors
- (2009) Kurt R. Brunden et al. EXPERIMENTAL NEUROLOGY
- Structural and functional changes in tau mutant mice neurons are not linked to the presence of NFTs
- (2009) A.B. Rocher et al. EXPERIMENTAL NEUROLOGY
- Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
- (2009) H. Chen et al. HUMAN MOLECULAR GENETICS
- Phosphorylated Tau Interacts with c-Jun N-terminal Kinase-interacting Protein 1 (JIP1) in Alzheimer Disease
- (2009) Lars M. Ittner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Caspase-cleaved Tau Expression Induces Mitochondrial Dysfunction in Immortalized Cortical Neurons
- (2009) Rodrigo A. Quintanilla et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Propagation of Tau Misfolding from the Outside to the Inside of a Cell
- (2009) Bess Frost et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Calcium in the initiation, progression and as an effector of Alzheimer’s disease pathology
- (2009) Kim N. Green JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Intracellular calcium signalling in Alzheimer’s disease
- (2009) Marina Hermes et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport
- (2009) Will Stoothoff et al. JOURNAL OF NEUROCHEMISTRY
- The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer’s disease
- (2009) Xinglong Wang et al. JOURNAL OF NEUROCHEMISTRY
- Tangle-Bearing Neurons Survive Despite Disruption of Membrane Integrity in a Mouse Model of Tauopathy
- (2009) Alix de Calignon et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Divergent Pathways Mediate Spine Alterations and Cell Death Induced by Amyloid- , Wild-Type Tau, and R406W Tau
- (2009) C. Tackenberg et al. JOURNAL OF NEUROSCIENCE
- Axonal Transport Defects in Neurodegenerative Diseases
- (2009) G. A. Morfini et al. JOURNAL OF NEUROSCIENCE
- Age-Dependent Impairment of Cognitive and Synaptic Function in the htau Mouse Model of Tau Pathology
- (2009) M. Polydoro et al. JOURNAL OF NEUROSCIENCE
- Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease
- (2009) X. Wang et al. JOURNAL OF NEUROSCIENCE
- Challenges in the conduct of disease-modifying trials in ad: Practical experience from a phase 2 trial of TAU-aggregation inhibitor therapy
- (2009) C. Wischik et al. Journal of Nutrition Health & Aging
- The role of tau in neurodegeneration
- (2009) Tania F Gendron et al. Molecular Neurodegeneration
- Transmission and spreading of tauopathy in transgenic mouse brain
- (2009) Florence Clavaguera et al. NATURE CELL BIOLOGY
- Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies
- (2009) Kurt R. Brunden et al. NATURE REVIEWS DRUG DISCOVERY
- Tau pathophysiology in neurodegeneration: a tangled issue
- (2009) Tara L. Spires-Jones et al. TRENDS IN NEUROSCIENCES
- In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons
- (2008) T. L. Spires-Jones et al. JOURNAL OF NEUROSCIENCE
- The Potential for -Structure in the Repeat Domain of Tau Protein Determines Aggregation, Synaptic Decay, Neuronal Loss, and Coassembly with Endogenous Tau in Inducible Mouse Models of Tauopathy
- (2008) M.-M. Mocanu et al. JOURNAL OF NEUROSCIENCE
- Axonal Transport Rates In Vivo Are Unaffected by Tau Deletion or Overexpression in Mice
- (2008) A. Yuan et al. JOURNAL OF NEUROSCIENCE
- The amino terminus of tau inhibits kinesin-dependent axonal transport: Implications for filament toxicity
- (2008) Nichole E. LaPointe et al. JOURNAL OF NEUROSCIENCE RESEARCH
- A Neuronal Microtubule-Interacting Agent, NAPVSIPQ, Reduces Tau Pathology and Enhances Cognitive Function in a Mouse Model of Alzheimer's Disease
- (2008) Y. Matsuoka et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells
- (2008) A. Gómez-Ramos et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease
- (2008) Melanie Meyer-Luehmann et al. NATURE
- Aβ Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks
- (2008) Kishore V. Kuchibhotla et al. NEURON
- Differential Regulation of Dynein and Kinesin Motor Proteins by Tau
- (2008) R. Dixit et al. SCIENCE
- Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease
- (2008) Ilya Bezprozvanny et al. TRENDS IN NEUROSCIENCES
- Tau inhibits anterograde axonal transport and perturbs stability in growing axonal neurites in part by displacing kinesin cargo: Neurofilaments attenuate tau-mediated neurite instability
- (2007) Maya Dubey et al. CELL MOTILITY AND THE CYTOSKELETON
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